Tuesday, August 18, 2026

An Excellent Analysis of Wokeness/P.C. & The Dem Plot To Pretend It Never Happened

This is a great summing-up of the destruction that "wokeness" has caused. I remember back further when it was called "political correctness," and adherents found the word "Christmas" offensive and demanded it be changed to "Winter Holiday"; thought the phrase "master bedroom" evoked slavery; and wanted to eliminate "Mothers Day" and "Fathers Day" for not being "inclusive."  Even words like "manhole cover" and "mailman" were found objectionable. And it's only gotten worse.

The author writes, " Don’t let them trick you into thinking it was just an oopsie-daisy." I'm not fooled by them because I know they actually believe the nonsense they spout.  The author also says, "What — you don’t think they’re actually sorry for what they did, do you?" No, they aren't sorry at all. This is just a ploy to somehow make themselves look less radical to voters in time for the state and national elections.  It's like how Mamdani tried to make himself sound less antisemitic before he was elected - and then let loose with a vile speech after he unfortunately won.

George Orwell wrote in "1984': ""Every record has been destroyed or falsified, every book has been rewritten, every picture has been repainted, every statue and street and building has been renamed, every date has been altered."  The radicals have done this, too, and they will continual to do so when they are elected or reelected.

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 ‘Woke One’ Wasn’t Just Crazy — It Was Destructive

National Review, by Becket Adams, August 18, 2026 6:30 AM

"Don’t let them trick you into thinking it was just an oopsie-daisy.

"We’re living through a real-life attempt to erase the recent past.

“Woke One was crazy,” Representative Alexandria Ocasio-Cortez (D., N.Y.) laughed recently during an appearance on ABC News, approvingly quoting a New York City councilman. “Woke One was crazy. Okay, that’s a truth,” ABC’s Jonathan Karl replied. The anchor then asked whether the left had gone too far during “Woke One,” including with its calls to “defund the police.”

"This is where Ocasio-Cortez — and many within her ideological cohort, whether it’s writers at Vanity Fair or the New Republic, or New York City Mayor Zohran Mamdani, or even failed Wisconsin gubernatorial candidate Francesca Hong — want you to accept their version of events over your own memory.

“I think that during this time and during, especially during Covid, there was a huge opening of the Overton window,” Ocasio-Cortez said. “We were shut down. There was some of the highest unemployment rates that we have seen because of those shutdowns. And I think that the doors were really open in trying to entertain any and every policy that was going to get us to a better place. And I actually think that the discussions that were had in that time were quite fruitful.”

"She added, “I think that when we talk about crime today, it’s fundamentally different than the way that we talked about crime in bringing crime down, right? And I think that we all share in the goals of having as low a crime rate as possible. I think that, you know, during lockdown, of course, rhetoric in that time is not rhetoric that we would use today.” 

"Total nonsense.

"She’s simply trying to rewrite the record, and it’s as dishonest as it’s brazen. It’s also glaringly obvious what this is: a cleanup effort by someone with aspirations for higher office.

Your Local Epidemiologist:The Dose, 8-18-26

Here's Dr Katelyn Jetelina with another informative issue of "The Dose".

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Covid-19 and dengue creeping up, vaccinations creeping down, a new mRNA flu vaccine, and more

The Dose (August 18)

As summer winds down, several diseases are winding up, like Covid-19 infections and rare mosquito-borne illnesses. Unfortunately, we can expect the same for vaccine-preventable diseases, according to new CDC data.

We also have some good news: the approval of a new mRNA flu vaccine. If you’re deciding whether to get it, there is some important nuance for you to consider.

Here’s your disease “weather report” and what it may mean for you and your family.


Disease weather report

Covid-19 wave is still small, but growing

Covid-19 levels (e.g., emergency department visits, wastewater transmission), remain low nationally but continue to rise in every state. The South and the West are the leaders, which is typical this time of year.

By the end of this wave, we can expect 10-15% of people to get infected. Thankfully, the number of hospitalizations isn’t nearly as high with population immunity, but Covid-19 remains serious for older adults, infants, and people who are immunocompromised.

Covid-19 wastewater levels. Source: Biobot.

Are Covid-19 metrics still useful for tracking waves? Yes, when used together. It’s true that fewer people and places are testing, but the positivity rate reflects the share of tests, which helps show the direction of trends. For wastewater, the number of sites has dipped slightly (from ~1,500 to 1,300), and funding is hanging on by a thread, but our systems still cover ~144 million people.

What this means for you: We are at the beginning of a Covid-19 wave. It’s not clear how small or big this will get, but if you’re high risk for severe disease, the time to get the vaccine is now.

Dengue cases creeping northward

It’s peak mosquito season. So rare mosquito-borne diseases like dengue (also known as “break-bone fever” due to severe joint pain) are popping up in the news, particularly in the Southern and Western U.S.

Last week, the first-ever non-travel-related case was reported in Virginia. A local mosquito bit a returning traveler with dengue, then bit another person nearby, and they got sick. This isn’t going to turn into an outbreak, because these mosquitoes only feed every few days, stay within a few hundred yards of where they hatched, and live just 2-4 weeks.

A few decades ago, epidemiologists would have been surprised to find locally acquired dengue in the U.S., as it was typically confined to the equator.

Mosquitoes in the U.S. have long been capable of carrying the disease (so infected mosquitoes aren’t marching northward from the equator), but the environment in the U.S. didn’t have conditions for the disease to thrive. Now, infected travelers combined with longer, warmer seasons create the perfect conditions for transmission. Scientists expect it to become increasingly common.

What this means for you: Dengue, or any mosquito-borne disease in the U.S., is very rare. Mosquitoes are mostly a nuisance. The name of the game is prevention of bites.

Vaccination rates continue to move backward

We can expect measles, whooping cough, and other vaccine-preventable diseases to continue to creep back up, according to CDC data released yesterday.

Some takeaways:

  1. Americans continue to vaccinate at high rates. The national MMR rate is 92.4%. (When was the last time that 92% of Americans agreed on something?) But all vaccines are decreasing by a tiny percent, and, in raw numbers, this means ~280,000 kindergarteners are unprotected.

  2. Exemption rates are climbing fast, though how fast varies widely by state. In Idaho, for instance, one in six kindergarteners is exempt from vaccines for religious or philosophical reasons. This is compared to near-zero rates in the five states, including California and West Virginia, that don’t allow such exemptions at all.

Vaccine exemptions in Idaho. Source: CDC.

What this means to you: The high national vaccination rates are great, but they mask state variability. And state rates mask local variability. Local rates (and unvaccinated, tight-knit pockets) are what really drive outbreaks, school disruptions, and costs to a county. This data is rarely available to parents and communities. I hope CDC is working on it, but in the meantime here is a tool from Washington Post to see where your community lands.


Spotlight on the new mRNA flu vaccine: The good, the not-so-great, and open questions

By now, you’ve probably seen the headlines: FDA approved the first mRNA flu shot (called mFlusiva) for older adults. Many people are excited about it. (It is great news!) Here is the nuance to help you make an evidence-based decision this fall.

The good: We needed better flu vaccines

In a large clinical trial, the mRNA flu vaccine was more effective than a standard vaccine at preventing symptoms in adults aged 50 and older: 2% of people who got mFlusiva developed flu, compared to 2.8% who got the standard shot. This equates to a 27% more effective vaccine.

This is good news because our standard flu vaccines aren’t that great at preventing infection. The flu virus mutates quickly, so flu vaccines can range from 15% to 60% effective each year, depending on how much the virus has changed over the 6 months it takes to make the vaccine and get it into arms. Any improvement is great. In addition, mRNA vaccine formulas can be updated in weeks, which would be enormous if we can adapt the annual policy pipeline to match that speed (or in case we get a flu pandemic).

The not-so-great: More side effects

If you’re like me and the mRNA Covid-19 vaccine knocked you out for a day or two, I have some unfortunate news: this one will probably do the same. That’s because, for some people, the immune system reacts to how mRNA vaccines are delivered into your cells (via lipid nanoparticles), leading to more inflammation.

Compared with a standard flu shot, the mRNA flu vaccine causes more injection-site pain (66% vs. 30%), fatigue (45% vs. 20%), and headaches (38% vs. 18%). Most of these side effects were mild and gone within a day or two, and no serious safety issues arose.

The open questions

1. How well does it work for seniors? It’s unclear.

For adults aged 50-64, the vaccine was fully approved because the clinical trial was straightforward: fewer people got sick.

For adults 65 and older, it’s messier. This group usually gets a high-dose flu shot, since their immune systems respond less strongly to a standard dose. But mFlusiva was never tested head-to-head against that high-dose shot in a clinical trial. Instead, it was approved for this age group based on high antibody levels tested in petri dishes. The mRNA flu vaccine has been shown to generate broader antibody responses than current vaccines, suggesting it could be more effective over time. The T cell response also seemed better. This will likely mean they are better, but we don’t have enough data yet to confirm this or answer “how much better?” FDA is requiring Moderna to run that head-to-head trial, but results won’t be in for a year or two. In the meantime, they authorized its use for people ages 65 and older through an accelerated approval.

2. Will people be able to get it this fall? Yes, maybe, I think?

For those aged 50-64, it’s unclear whether this will be widely available. Traditionally, ACIP has to recommend a new vaccine for insurance to cover it and for physicians to order it. But ACIP isn’t functioning because of a legal dispute between AAP and RFK Jr. It’s unclear what happens in fall.

For those 65 and older, there is a loophole: flu vaccine coverage under Medicare Part B is written directly into the law. It doesn’t depend on ACIP. That means people 65+ on Medicare should be able to get it this fall at no cost.

3. Will people actually get vaccinated?

This is the elephant in the room: flu vaccination rates are decreasing across the country at staggering rates. Shiny new biotechnology is cool, but not if people don’t use it.

What this means for you: A new mRNA flu vaccine should be available to those 65 years and older this fall.


Poll


Bottom line

Covid-19 is resurging, rare mosquito-borne diseases are gaining ground, and illnesses from the 19th century are making an unwelcome return. The tools to stop them exist (and new ones are coming), but the question is whether we’ll use them.

Love, YLE


Your Local Epidemiologist (YLE) comprises a team of experts, ranging from physicians to immunologists to epidemiologists to nutritionists, working together with one goal: to “translate” ever-evolving public health science so that people are well-equipped to make evidence-based decisions. The YLE suite of newsletters reaches over 475,000 people across more than 132 countries. This newsletter is free to everyone, thanks to the generous support of fellow YLE community members.

Dr Ruth Report, 8-17-26

Here's Dr Ruth Ann Crystal with another timely medical report.  As usual, she has compiled an impressive amount of helpful information. The high levels of COVID in the wastewater of certain states are staggering -- and frightening.

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Dr. Ruth Report, 8/17/26

The summer COVID wave has arrived, especially in the West and the South, as seen by increasing levels of SARS-CoV-2 virus in wastewater. We are starting from a lower baseline of COVID in wastewater with this wave.

Nationally, Emergency Department visits for COVID are very low, but are now increasing. Mike Hoerger estimates that on 8/8/26, every 1 in 144 people were infectious with COVID nationally, but there are hot spots, especially in the West and the South, where more people are sick with COVID now. For example, Dr. Hoerger estimated that as of 8/8/26, every 1 in 49 people in California were infected with COVID, although wastewater levels have increased since then.

The highest reported level of COVID in wastewater 8/16/26 on WastewaterSCAN was in Anchorage, AK where levels were an astronomical 10,450 PMMoV. New Orleans was at a whopping 862 PMMoV, Honolulu HI is at 382, Oceanside San Francisco at 351, San Rafael CA at 335, Pascagoula MS at 329 and Oakhurst NJ at 283 PMMoV.

KQED warns “Yes, That ‘Summer Cold’ Really Might Be COVID (Again). What to Know About Bay Area Viral Levels.”

Acute COVID infections, General COVID info

Divergent responses to SARS-CoV-2 infection reveal brain resilience-associated astrocyte programs in centenarians | Stem Cell Reviews and Reports Preprint 8/12/26

  • Scientists generated brain astrocytes from iPSC stem cells made from blood samples of centenarians (≥100 years) who had mild COVID and from younger adults under 45 who had critical illness. When infected with SARS-CoV-2, the centenarian astrocytes better controlled inflammation and showed fewer stress related protein changes, suggesting their astrocytes carry built in resilience against severe viral damage.

Vaccines

COVID vaccination may have prevented more than 4,000 deaths in one Washington county | CIDRAP 8/13/26

  • A new study shows that COVID vaccination may have prevented 20,000 severe outcomes and more than 4,000 deaths in one county in Washington state.

Antiviral treatments

The monoclonal antibody VYD2311 potently neutralizes dominant and emerging SARS-CoV-2 variants | JCI Insight 8/11/26 (David Ho’s lab)

  • Researchers from David Ho’s lab at Columbia University demonstrated in vitro that the monoclonal antibody VYD2311 from Invivyd successfully neutralized all seven recent SARS-CoV-2 variants evaluated, including XFG, NB.1.8.1, and BA.3.2.2. Across all variants tested, VYD2311 achieved neutralization at substantially greater potency than pemivibart (Pemgarda).

Organoid-based evaluation of [monoclonal antibodies] SA55 and Pemivibart against evolving SARS-CoV-2 variants | Emerging Microbes & Infection 8/3/26

  • Researchers from the University of Hong Kong tested two monoclonal antibodies against current SARS-CoV-2 subvariants in nasal organoids, finding that Pemivibart, the only FDA authorized antibody currently in use under Emergency Use Authorization, has lost 60 to 80 times its effectiveness against the XFG and KP.3.1.1 subvariants. Monoclonal antibody SA55 has retained strong potency and when delivered topically reduced SARS-CoV-2 viral load by more than 1,000 fold, suggesting it may offer a more durable option as the virus continues to evolve.

Long COVID

Multiomic and Spatial Profiling of Colorectal Tissue Reveals Viral Persistence and Immune Dysregulation in Long COVID | BioRxiV (UCSF) 8/10/26

An important new UCSF study of colorectal biopsies and blood from 44 people with Long COVID and 13 recovered controls found lingering SARS-CoV-2 RNA in 27% of Long COVID patients’ gut biopsies versus 7.7% of controls. The gut tissues with the viral remnants showed a skewed immune response with active innate inflammation, yet blunted adaptive clearance pointing to viral reservoirs that the immune system can sense, but cannot eliminate. The researchers identified 240 significantly altered genes in colorectal tissue biopsies, but only three in matched peripheral blood immune cells, suggesting that the pathophysiology of Long COVID may be compartmentalized within tissues and not within the blood.

Since the gastrointestinal tract is 25 to 30 feet long, random biopsy sampling may have missed areas of infected tissue in some patients. Small intestinal tissue turns over very quickly, so any virus seen on gut biopsy would most likely be related to a recent SARS-CoV-2 infection or seeding of the bowel.

The findings of this study support that in order to rid the body of viral reservoirs in gastrointestinal tissues in people with Long COVID, treatments may need to target both the persistent virus (with antivirals) and the immune dysfunction within tissues (with immune boosting medications).

Explainer article:

New Study Reveals Substantial Tissue-Level Immune Dysfunction Near Persistent Viral Reservoirs in Long COVID | PolyBio Research Foundation 8/11/26

  • It appears that there may be viral reservoirs of SARS-CoV-2 along the gastrointestinal tract in people with Long COVID that the immune system can see, but cannot eliminate. Using antiviral medication together with medications to boost immune response may be needed to help clear Long COVID.

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Virus reactivation in acute and long COVID-19 | Nature (Melamed) 8/5/26

  • A large IMPACC cohort study (1,154 hospitalized COVID-19 patients) found widespread reactivation of herpesviruses (EBV at the time of hospitalization and CMV a few weeks later) and Anelloviruses during acute COVID illness, tracking with severity and inflammation, even in immunocompetent patients. Reactivation persisted into convalescence, and Anellovirus transcripts were linked to Long COVID fatigue and physical disability, suggesting a possible biomarker.

Explainer article: COVID-19 can wake up dormant viruses in the body, large study confirms | Science 8/5/26

VSL#3® supplementation improves fatigue in long COVID: results from the DELong#3 randomized placebo-controlled trial | British J of Biomedical Science 7/27/26

  • Fondazione IRCCS Ca’ Granda in Milan enrolled 48 Long COVID patients in a randomized, placebo controlled trial finding that four weeks of high dose VSL#3 probiotic supplementation reduced fatigue in 68% of participants compared to 35.7% in the placebo group. Patients who responded to treatment also demonstrated measurable changes in gut microbiota composition and immune signaling markers.

👁️Subclinical neurovascular and immune correlates of post-COVID-19 syndrome detected by retinal imaging | Brain, Behaviour & Immunity- Health 8/6/26 “October 2026”

  • Researchers from Munich studied 128 participants and found that individuals with Long COVID showed measurable thinning of retinal nerve fiber layers alongside reduced macular volume compared to controls. Elevated levels of MCP-1, a protein associated with ongoing inflammatory activity, were specifically correlated with reduced thickness in the inner retinal layers, suggesting a detectable biological signature of post-COVID neurological involvement visible through eye imaging.

💪Persistent neuromuscular dysfunction in long COVID: A quantitative and single fiber EMG follow-up study | Clinical Neurophysiology 8/5/26

  • Danish scientists followed 50 Long COVID patients over approximately 1.4 years and found that myopathic EMG abnormalities dropped from 78% to 18% of participants. However, 56% of patients continued to show abnormal single fiber EMG (SFEMG) results alongside persistent fatigue, indicating that measurable neuromuscular dysfunction had not resolved even as some electrical markers improved. “Although SFEMG abnormalities persisted in the majority of patients, 40% showed normalization of objective neurophysiological parameters despite unchanged subjective fatigue symptoms, highlighting the discrepancy between electrophysiological recovery and patient-reported outcomes.”

🧠Identifying EEG biomarkers of fatigue and brain fog in long COVID: insights from rest and movement-related brain activity | J Clin Neurosci “Nov 2026” (8/12/26)

  • McGill University researchers studied 40 participants (20 Long COVID participants with fatigue, brain fog, and post-exertional malaise (PEM) vs. 20 age and sex-matched controls) and found a Long COVID signature on EEG. People with Long COVID displayed a reduced beta wave rebound following movement and a slower alpha rhythm at rest in the sensorimotor cortex, both of which signal compromised neural inhibition. These brain activity patterns corresponded directly to greater severity of fatigue and cognitive impairment in affected individuals.

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🧠Long COVID affects working memory: assessment using a single rapid online test | Frontiers In Human Neuroscience 7/22/26

  • University of York scientists studied 1,064 participants and found that a Long COVID diagnosis was the single strongest predictor of reduced working memory performance. Patients who had been formally diagnosed with Long COVID scored lowest overall, and those who had experienced more SARS-CoV-2 infections showed progressively worse memory outcomes within that group.

🧠Neuropsychological consequences three years post-covid-19 are persistent and have great impact on everyday activities | Journal of Rehabilitation Medicine 8/3/26

  • Researchers from the University of Gothenburg followed 82 individuals recovering from COVID, with 59 completing testing at the three year mark. Standardized assessments showed ongoing impairments in attention, processing speed, and working memory, and 78% of participants still scored above the threshold for mental fatigue. These deficits pose substantial barriers to daily functioning and return to work, highlighting the need for targeted rehabilitation strategies.

🫀Changes in Subclinical Biomarkers of Myocardial Injury and Inflammation and SARS-COV-2 Serological Analyses in a Cohort of Community-dwelling Adults | Nature Preprint 7/29/26.

  • Johns Hopkins scientists tracked 607 adults and found that those with prior SARS-CoV-2 infection showed significantly greater increases in NT-proBNP, a biomarker indicating stress on the heart walls, over a six-month follow-up period. This elevation in cardiac strain was observed even among individuals who had experienced mild or asymptomatic infections, raising questions about cardiovascular consequences beyond severe hospitalized cases.

🦴Multiscale bone remodeling in COVID-19: from osteoimmune signaling to structural and mechanical impairment | Frontiers in Bioengineering and Biotechnology 7/21/26

  • Researchers at Politecnico di Milano reviewed emerging evidence on COVID and bone health. SARS-CoV-2 can weaken bone through both direct effects, such as inflammatory activation of bone-resorbing cells, and indirect pathways, including renin-angiotensin system disruption, corticosteroid exposure, and prolonged bed rest. Findings included reduced bone density, altered microarchitecture, and disrupted osteocyte signaling.

Effects of SARS-CoV-2 infection on femoral trabecular bone parameters in animal models: C) Time-course micro-CT imaging at 4-, 30-, and 60-day post-infection (dpi) illustrates progressive deterioration of trabecular structure in femur bone.

From: https://www.frontiersin.org/journals/bioengineering-and-biotechnology/articles/10.3389/fbioe.2026.1812439/full

COVID-19 Associations With Thyroid Disease in Active-Duty Service Members: A Retrospective Cohort Study | Military Medicine 8/6/26

  • Uniformed Services University analyzed data from 687,531 matched adults and found that COVID infection was linked to a significantly elevated risk of newly diagnosed thyroid disease. Among active duty military personnel specifically, the hazard of developing thyroid conditions rose by 48%, with diagnoses typically appearing five to six months after infection.

Measles

CDC Measles Update

  • As of August 13, 2026, 2,566 confirmed measles cases were reported in the United States in 2026.

Johns Hopkins US Measles Tracker:

Ebola in Democratic Republic of Congo (DRC)

8/14/26 RDC update: “To date, 4,843 confirmed [Ebola] cases have been recorded. 777 patients are currently in isolation or hospitalized, 1,006 people have been cured since the start of the epidemic, and 2,272 deaths have been recorded. The case fatality rate stands at 46.9%, while the contact tracing rate reaches 83.2%.”

DR Congo Ebola outbreak on track to be largest in history | CIDRAP 8/12/26

  • WHO Director-General Tedros says DR Congo’s Ebola outbreak is on pace to surpass the 2014-16 West African outbreak, which killed over 11,000 people. WHO reports 4,449 confirmed cases and 2,061 deaths across five provinces in the current outbreak. Most deaths occur in the community, signaling unknown transmission chains and incomplete contact tracing, now at around 80%.

Cyclosporiasis

According to YLE, nationwide Cyclosporiasis cases have topped 20,000 this year, likely making this the largest foodborne outbreak on record, with counts still rising as Michigan investigators clear a case backlog. The contaminated lettuce appears cleared from circulation, though, as test positivity and emergency department visits have both declined sharply.

Salmonella in Jalapeños

A Salmonella outbreak linked to fresh jalapeños from Sinaloa, Mexico has sickened 345 people across 27 states, with 36 hospitalized and two antibiotic-resistant cases. Salmonella causes diarrhea, fever, and stomach cramps. Symptoms start 6 hours to a few days after eating contaminated food and may last for 4 to 7 days. Chipotle, Qdoba, and several prepared-food brands have recalled affected products. It may be best to avoid purchasing jalapenos, and associated foods like fresh salsas, until this salmonella outbreak is under control.

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Government Health News

Trump wants MMR vaccine split up: the science behind why it’s a bad idea | Nature 8/12/26

As measles outbreaks grow across the United States, President Trump issued an executive order on 8/10/26 pushing states to recommend splitting the MMR vaccine into three separate shots at separate appointments, an option which is not even currently available. Years of evidence have confirmed that the MMR vaccine is safe and effective as given.

Splitting the vaccine would mean more doctor visits, and studies show this lowers full vaccination rates, especially among lower income families, leaving those communities more vulnerable. The order will not actually change CDC recommendations or, likely, insurance coverage. Its main effect will be to sow further confusion about vaccines.

Evaluating the impact of two decades of USAID interventions and projecting the effects of defunding on mortality up to 2030: a retrospective impact evaluation and forecasting analysis | Lancet 7/19/26

  • “USAID funding has significantly contributed to the reduction in adult and child mortality across low-income and middle-income countries over the past two decades. Our estimates show that, unless the abrupt funding cuts announced and implemented in the first half of 2025 are reversed, a staggering number [14 million additional deaths, including 4.5 million children] of avoidable deaths could occur by 2030.”

Other news

UK records hottest day of the year as fifth heatwave reaches 38.1C [100.6F] peak

Diagnosis of Celiac Disease | JAMA 8/12/26

  • “JAMA Insights: For selected patients with Celiac Disease, serology may support diagnosis, but biopsy remains important for patients with immunoglobulin A deficiency, alarm symptoms, or certain autoimmune or chromosomal disorders.”

CAR T cell therapy beyond cancer: current status, challenges and future prospects | Signal Transduction and Targeted Therapy 8/11/26

  • Researchers are investigating whether CAR-T cell therapy can be repurposed to eliminate two categories of disease sustaining cells: viral reservoir cells that harbor latent infections and autoreactive B cells or plasma cells that drive autoimmune conditions. The goal is a lasting biological reset of the immune system rather than ongoing symptom management.

Antigen presentation at the blood–brain barrier amplifies neuroinflammation | Trends in Immunology 8/6/26

  • A review from UCSD shows that inflamed blood vessels in the brain can display antigens directly to CD8 T cells, extending the duration of contact between those immune cells and the blood–brain barrier and causing barrier damage in the process. This mechanism appears to stoke existing neuroinflammation rather than initially trigger it.

Weight-loss-independent actions of GLP-1 medicines | Cell Metabolism 8/4/26

  • A new Cell Metabolism study reveals that GLP-1 receptor agonists deliver measurable benefits to the heart, liver, kidneys, blood vessels, and immune system through direct biological pathways that operate separately from any reduction in body weight. These medicines appear to activate neural circuits, local organ receptors, and cross-organ signaling networks that collectively improve glucose regulation, blood pressure, and inflammatory responses across multiple body systems.

From: https://www.cell.com/cell-metabolism/fulltext/S1550-4131(26)00279-2

Vaccines to intercept colon cancer before it takes root are in the testing stage | LA Times 8/13/26

  • Scientists at MD Anderson Cancer Center and sites in Britain are testing vaccines designed to intercept colon cancer in people with Lynch syndrome, an inherited mutation affecting about 1 million Americans, before tumors form. Three candidate vaccines are in early trials, with a larger study expected to begin next year.

Fecal microbiome transplant in food allergy in humans and mice identifies a role for bile acid metabolites in oral tolerance | Science Translational Medicine 8/5/26

  • A clinical study of 15 peanut allergic adults found that fecal microbiome transplants (FMT) enabled 6 participants to tolerate greater peanut exposure than before treatment. Mechanistic work in mice revealed that Bacteroides species drive bile acid metabolism to elevate regulatory T cells, and this pathway was necessary for the observed protection against allergic response.

‘It just makes sense!’: 13-year old builds 3D printed wheelchair for 21 month old girl | ABC4 8/4/26

  • Thirteen year old Zac Waters of Lehi, Utah spent 300 hours this summer designing, 3D printing, and assembling a custom wheelchair for a 21 month old girl, using a design from the nonprofit MakeGood. The chair features pink accents, a removable tray table, and adjustable straps and footrest for comfort as she grows.

Photo by ABC4

Have a good week,

Ruth Ann Crystal MD

Monday, August 17, 2026

One of The Greatest Generation, A Dachau Liberator Speaks

No matter how many times I have heard and read these stories over the years, I am always moved at the quiet heroism of the rescuers and the survivors, whose numbers are steadily dwindling.

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One of Dachau’s last living liberators still has somewhere to be. For decades, Hilbert ‘Hibby’ Margol kept quiet about what he saw in 1945. Now, at 102, the WWII veteran is racing to tell his story while he still can 

By Benyamin Cohen, 8-10-26, The Forward

Hilbert "Hibby" Margol at his home in Atlanta. 

"ATLANTA — Hilbert “Hibby” Margol wears two watches.

"It is the kind of detail that seems small until you can’t stop noticing it. One watch is ordinary. It has hands, numbers, the plain mechanics of telling time. The other is a Life Alert, the sort of device sold to people who live alone, or to the people who love them and can’t stand the thought of them living alone.

"Together the two watches say something about a man before he’s said a word himself: that he has outlived the need for almost everything, except the people determined to make sure he’s still here.

"He is 102. He lives by himself in the same two-story house in suburban Atlanta he shared with his wife of 77 years, Betty Ann, who died at 96 last September. The house still carries the warmth of her memory. Family photographs cover every surface that will hold them: the mantel, the end tables, the walls, climbing toward the ceiling like something that grew there on its own.

"There will soon be one more: Hibby’s fourth great-granddaughter, Callie Rose, was born two weeks ago.

"A framed photograph of French President Emmanuel Macron pinning the Legion d’Honneur to Margol’s chest — taken in 2024, when Margol was one of dozens of American veterans Delta Airlines chartered to Normandy for the 80th anniversary of D-Day — leans against the fireplace, not yet hung, as if the house has simply run out of room to keep up with the life still happening inside it.

"The coffee table has disappeared beneath medals and ephemera and the accumulated evidence of a hundred years, and it occurs to you, sitting across from him, that you are not in the home of a man winding down. You are in the home of a man still arriving.

The coffee table at the home of Hilbert 'Hibby' Margol is lined with ephemera from his years of service.
The coffee table at the home of Hilbert ‘Hibby’ Margol is lined with ephemera from
his years of service. Photo by Benyamin Cohen

"His iPhone buzzed. Then again. He glanced at it and rolled his eyes.

“That’s my daughter,” he said. “Checking on me.”

"His daughter is, herself, a senior citizen. The phone had no case — hadn’t needed one, he doesn’t drop things — which felt like its own kind of answer to a question I hadn’t yet asked: What does it look like to move through a century without ever quite losing your grip?

"On the day I visited this June, he had just returned from yet another trip to Normandy, marking another anniversary of a war he’d fought in as a young man and had spent most of the rest of his life not talking about. A week before that, the Atlanta Braves had honored him on the field on Memorial Day for the second year in a row.

Left to right: Scott Johnson of the Warrior Alliance, Chris Sale of the Atlanta Braves and Hilbert 'Hibby' Margol before a baseball game honoring veterans in May 2025 at Truist Park in Atlanta, Georgia.
Left to right: Scott Johnson of the Warrior Alliance, Chris Sale of the Atlanta Braves
and Hilbert ‘Hibby’ Margol before a baseball game honoring veterans in May 2025
at Truist Park in Atlanta. Photo by David J. Griffin/Icon Sportswire via Getty Images

"For six decades, Margol said almost nothing about what he had seen at the end of that war — not to his wife, not to his three children, not to anyone. And then, in his 80s, he started to talk about it, and he has not really stopped since.

"Margol is sharing his experience as one of a dwindling number of U.S. Army veterans alive today who helped liberate the Dachau concentration camp.

Inside the camp

"He and his identical twin brother, Howard — younger by ten minutes — served together in the war. That alone took some doing: the military generally kept siblings apart, a policy hardened after five Sullivan brothers died together when their ship sank in 1942. (It’s loosely the premise behind Saving Private Ryan.) It took a letter from the Margols’ mother to President Franklin D. Roosevelt to get an exception made.

"On the morning of April 29, 1945, the brothers were on the outskirts of Munich when they caught a strange, powerful smell drifting out of the woods.

Twin brothers, Howard (left) and Hibby Margol, served in the U.S. Army during World War II.
Twin brothers Howard (left) and Hibby Margol served together in the U.S. Army
during World War II. Courtesy of Jerry Margol

"Howard was the one who placed it. It reminded him of an unpleasant odor he would sometimes catch a whiff of in their mother’s kosher kitchen back home in Jacksonville, Florida — the way she would hold a freshly killed chicken over the gas flame of the stove to singe off the last of its pin feathers. Only this stench was much, much stronger.

"The brothers went to find the source. What they came to first was a line of boxcars. The first one they reached had its sliding door open. A dead man’s leg was dangling out of it. They opened the cars and found them packed with dead bodies in striped prisoner uniforms “like sardines,” Hibby would say.

"They had a small camera, liberated from a dead German officer a few weeks earlier, and they used it to take a photograph of one of the cars — a copy of which hangs in the United States Holocaust Memorial Museum in Washington, D.C.

"They pressed further into the woods and came out at another clearing. Above the entrance was a sign: ARBEIT MACHT FREI. Work will set you free.

"They had found Dachau.

"Beyond the gate was a wide-open yard ringed by low barracks buildings — and, in several places, bodies stacked the way you’d stack cordwood. The arrangement of them is the part that refused to make sense. Somebody had piled them, neatly, as routine.

"Neither brother had ever seen anything like it. “We didn’t understand what we were looking at,” Margol said. “It sort of reminded us of a movie set.”

"They learned only later that the camp’s ovens had run out of coal months earlier, and without coal, there was no way to cremate the bodies. So the corpses had simply been left where they lay.

"It took a moment to register that not everyone in the yard was dead. Off to one side, against a barracks wall, were four or five prisoners — some squatting, some just standing, none of them well. But alive.

"The camp’s roughly 32,000 prisoners walked free later that same day, once a Swiss Red Cross negotiator talked the SS commander into a peaceful surrender rather than a last stand.

Liberated prisoners at the Dachau concentration camp raise bottles of wine and celebrate in 1945.
Liberated prisoners at the Dachau concentration camp raise bottles of wine 
and celebrate in 1945. Photo by Universal History Archive/
Universal Images Group via Getty Images

"Years later, at a visit to mark the liberation’s 70th anniversary, an elderly survivor found Margol after a memorial service. She told him she’d been too sick with typhus that morning to understand what was happening around her. Then she leaned over and kissed him on both cheeks. “If you guys were two or three days later,” she told him, “I wouldn’t have made it.”

One family, two branches

"I’ve spent much of the past year following a different story: a family of cattle farmers in rural Illinois, building a synagogue in a two-acre cornfield out of the remains of closing synagogues — a Torah rescued from one congregation, an ark from another, stained-glass windows carried out of buildings that no longer exist. The building will also include a museum of tolerance, sharing the stories of the family’s ancestors — some who died in concentration camps, others who survived by being hidden in the homes of Christian families.

"The family is named Jakobs. You’ve met the 41-year-old farmer, Nik, in stories I’ve written about the Pennsylvania synagogue he dismantled, piece by piece, to save it; the groundbreaking of the new one rising in a field; and the family’s roots in the Netherlands, where his grandmother, Edith, spent nearly three years hidden in a farmhouse. This spring, I flew with the family to Stadskanaal, the small Dutch town that was her family’s refuge, to watch a local theater troupe stage a play about her survival.

Nik Jakobs, a cattle farmer in rural Illinois, is building a synagogue in a two-acre cornfield.
Nik Jakobs, a cattle farmer in rural Illinois, is building a synagogue 
in a two-acre cornfield. Photo by Benyamin Cohen

"It was in the Netherlands, reporting Jakobs’ story, that he first mentioned a name: Hibby. Jakob’s brother Bryce who left the farm for a career of his own, is married to one of Margol’s granddaughters. Margol’s great-granddaughters carry both halves of this history. On one side: relatives murdered in the Holocaust, and ancestors who survived it in hiding. On the other: a soldier who helped liberate one of the camps.

"I asked Margol what he made of it. He didn’t reach for anything grand. “Well,” he said, “it’s quite a story.”

The silence

"For decades, Margol said almost nothing about Dachau to his family. “We had written letters,” he said of the war years. “We figured that was sufficient.”

"Life moved on. Margol built a business selling furniture and appliances. He raised a family. The war became something that had happened to a younger man.

"Then came an invitation.

"In 2012, at 88, Margol joined about a dozen other American liberators on the International March of the Living, traveling to Poland with Holocaust survivors and thousands of Jewish teenagers. For the first time since the war, he wasn’t simply remembering what he’d witnessed. He was walking beside people whose lives had continued because soldiers like him had arrived when they did.

“It was such an emotional experience,” he later recalled of walking from Auschwitz to Birkenau, “that when I got home I said, now I have to start talking about it.”

"His first talk was at the public library near his home. More than 90 people showed up, on word of mouth alone. Then came another invitation. And another. Synagogues. Churches. High schools. A World War II roundtable. Adult education classes at Emory University. He stopped counting after 200 presentations. Today, he estimates he’s given close to 300.

German President Frank-Walter Steinmeier, right, greets Fred J. Nungesser Jr. in the presence of, left to right, Hilbert 'Hibby' Margol, Frank Arthur Athanason, Gideon Kantor and Enoch 'Woody' Woodhouse during a reception for U.S. veterans of World War II at Bellevue Palace in Berlin in Nov. 2025.
German President Frank-Walter Steinmeier, right, greets Fred J. Nungesser Jr. 
in the presence of, left to right, 
Hilbert ‘Hibby’ Margol, Frank Arthur Athanason, Gideon Kantor and 
Enoch ‘Woody’ Woodhouse during a reception for U.S. veterans of World War II
at Bellevue Palace in Berlin in Nov. 2025.
Photo by Sebastian Gollnow/picture alliance via Getty Images

"But talking about Dachau and reliving it are not the same thing. Years ago, touring the United States Holocaust Memorial Museum in Washington, D.C., with a small group, he had to walk through a boxcar on exhibit to continue the tour — cleaner and newer-looking than the one he remembered, but a boxcar all the same. “Emotionally,” he said, “I broke down.”

"For most of his life, Margol had carried the story alone. Now he worried what would happen if no one carried it after him.

"In September, Margol is returning to Germany with his son Jerry, 74 — this trip courtesy of the Best Defense Foundation, the veterans organization that has taken the two of them to battlefields around Europe, and which is now making a documentary about Margol and another veteran. The itinerary is still coming together, but it includes a stop that father and son have made together twice before: Dachau.

The next generation

"Long before Margol began speaking publicly about the Holocaust, he had already spent years building Jewish life closer to home.

"Rabbi Mark Zimmerman saw it firsthand. Zimmerman retired this summer after leading Congregation Beth Shalom in Atlanta for 38 years. He met Margol in 1988, when the rabbi arrived and Margol was, as he put it, “a young man of sixty-something.”

“He still comes to synagogue,” Zimmerman said. “He’s still sharp as a tack.”

"But what Zimmerman remembers most isn’t Margol’s longevity. It’s what he built.

"In the late 1990s, Beth Shalom needed an educational wing. Before the congregation had raised a dollar toward the project, Margol quietly wrote a $100,000 check so the synagogue could hire a professional fundraiser and launch the campaign. He and fellow congregant Stephen Klein later donated roughly $350,000 each to complete the building.

"Today the Klein-Margol Educational Wing houses the congregation’s preschool, administrative offices, chapel, library and youth lounge.

“In many ways,” Zimmerman said, “I owe my staying at Beth Shalom to Hibby and his vision. We still have a tremendous preschool because of that original vision.”

"Only years later did Zimmerman learn another part of Margol’s legacy, about liberating Dachau. Margol recently gave Zimmerman a copy of the memoir he and his son self-published, becoming one of the congregation’s living links to the Holocaust.

“His firsthand account is such a rare commodity,” Zimmerman said, “in a world where primary witnesses, for the most part, are dying out.”

"Nearly 800 miles away, in Sterling, Illinois, the other side of Margol’s family is at work on a version of the same project. Jakobs is building a synagogue, with a museum inside so his grandmother’s story outlives her. Margol has already seen how it turns out — his wing has held preschoolers for a quarter century. Jakobs broke ground this spring.

A hat, a promise

"I asked Margol if I could take his picture before I left. “Let me get my baseball hat,” he said, and disappeared into another part of the house.

"It’s the one with the patch of the 42nd Infantry Division — the Rainbow Division, one of the liberating forces at Dachau. The nickname dates to 1917, coined by a young Col. Douglas MacArthur because the division’s ranks were drawn from National Guard units in 27 different states.

"Room by room, the 102-year-old wandered through his home looking for the hat. He checked the kitchen. He looked at the hook by the door, where another cap was hanging, then shook his head and kept going.

"There was something almost unbearably ordinary about it, set against everything he’d just spent hours telling me. The boxcars. The smell. The gate. And now: Where did I put that hat?

"He found it, and came back into the room wearing it — the same hat, more or less, that has sat on his head in front of hundreds of audiences by now. He still says yes to the invitations. He still boards planes to Europe. When I asked what all of it was for, he didn’t hesitate.

“I hope and pray,” he said, “that the offspring of all the Holocaust survivors outlive the offspring of the deniers.”

Hilbert 'Hibby' Margol wearing a hat and jacket with the patch of the 42nd Infantry Division — the Rainbow Division, one of the liberating forces at Dachau.
Hilbert ‘Hibby’ Margol wearing a hat and jacket with the patch of the 
42nd Infantry Division - — the Rainbow Division, one of the liberating 
forces at Dachau. Photo by Benyamin Cohen