Thursday, June 18, 2026

An Excellent Jonathan Tobin Column

Who will stand with Israel against a new Iran deal?
Back in 2015, the GOP and most Americans opposed Obama’s appeasement of Tehran. Now, Democrats are against Israel on any issue, and Republicans will not defy Trump.

Jonathan S. Tobin 

"In the never-ending churning of news cycles, commentators and the public alike are always ready to overreact to each aspect of every story as they roll out. Under these circumstances, historical perspective is rarely part of anyone’s understanding of events. This was amply illustrated by the discussion about the United States signing a Memorandum of Understanding with Iran.

"The deal, whose terms were at first kept secret and have since been revealed, will conclude, at least for the next 60 days, the war America and Israel waged on Tehran starting on Feb. 28.

"Hysteria about the implications of the deal for Israel, which was cut out of the negotiations over the agreement, is probably unwise. It’s not clear how much of the Jewish state’s freedom of action to defend itself against Iran, as well as its Hezbollah auxiliaries in Lebanon and Hamas in Gaza, will be curtailed. Nor can we know for sure what President Donald Trump will do in the immediate future.

Trump’s priorities

"His desire to end the fighting and for the renewed flow of oil to lower gas prices at the pump appears to be his main priority. For the moment, that seems to outweigh concerns about his desperation to get a deal that will accomplish these goals, which led him to strike a bargain that bears a troubling resemblance to the one former President Barack Obama concluded with Tehran in 2015.

"Trump can always change his mind about that and order strikes once it becomes clear—as anyone who knows anything about the subject understands—that Iran’s leaders have no intention of keeping their word about not acquiring a nuclear weapon. Though his public comments about the agreement make that seem highly unlikely, given the president’s panic about his sinking poll numbers linked to the rise in gas prices. But it’s still theoretically possible. It’s also a dead certainty that it will continue its buildup of missiles and terrorism that threaten its neighbors and the West.

"There is one thing, however, that can be said with absolute certainty about the current situation. Now that we know the deal is as bad as many feared, those who speak up against it are not only in no position to stop or even slow the process down. They will also be far more isolated than those who opposed Obama’s deal.

"Simply put, unlike the situation 11 years ago—when a broad coalition of Democratic security hawks, Republicans and pro-Israel advocates spoke up against Obama’s disastrous Joint Comprehensive Plan of Action—critics of Trump’s Iran deal will be limited to the pro-Israel community. And they are likely to stand alone.

Unpersuasive advocates

"Trump and Vice President JD Vance have been doing their best to fend off criticism of their decision to end the war with what the former described as a “peace deal” with the Islamist terror regime. That effort was undermined by their initial unwillingness to reveal details of the agreement—something that Vance claimed was due to sensitivities in the Muslim world, an excuse that raised even more concerns about its implications.

"Trump’s supporters have been telling everyone who has criticized the deal in the days since it was announced to take a deep breath, and to wait and see what happens. There’s a certain logic to that. The structure of the accord appears to hinge on what will happen during a 60-day period when America lifts its blockade of Iranian ports so Tehran stops menacing shipping in the Strait of Hormuz. Yet now that the details are known—with unfrozen funds already flowing to Iran, no mention of Iranian missiles and terrorism in it, and no mechanism, other than a resumption of the war, to prevent a regime that can claim it forced Trump to back down from resuming its march to a nuclear weapon—optimism about it seems deeply unpersuasive.

"In theory, Trump could reverse his decision, and sensible observers should not abandon all hope that he will. Accepting a terrible deal—and the terms of the agreement make it clear that the United States is doing almost all of the giving and Iran nearly all of the taking—would be out of character for a man who thinks of himself as having mastered “the art of the deal.”

"With Trump’s characteristic hyperbole, he has characterized the results of the indirect negotiations conducted by Middle East special envoy Steve Witkoff and adviser/son-in-law Jared Kushner in flattering terms. He has even declared the Iranian negotiators to be “rational people” who are “nice to deal with,” even though the desperate-for-a-deal-at-any-price duo never actually sat down with them. But the man who spent the last decade rightly mocking Obama and his negotiators for their weakness and gullibility ought to be ashamed of accepting terms that seem to depend on Iran’s goodwill and trustworthiness.

"Trump’s critics should acknowledge that not only is the current president far preferable to his Democratic predecessors or to any Democratic Party alternative when it comes to his approach to the Middle East and Israel. They should be equally willing to speak of the damage done to Iran’s military, nuclear and missile programs, and other war-making infrastructure both as part of the 12-day war last June and from the fighting since Feb. 28. The ability of a government that has been at war with the United States, Israel and the West since 1979 to inflict terror on the region and the rest of the world has been set back, perhaps by years.

"At the same time, Israel is far stronger vis-à-vis its Islamist foes than it was on Oct. 6, 2023, before the Iranians and their allies launched their cruel war on the Jewish state with the atrocities of Oct. 7.

"Still, it appears that Trump has kicked the can down the road with respect to ending the threat from Iran. And it is also almost certainly true that despite raising the hopes of Iran’s tortured people, he has nevertheless ensured the survival of a despotic regime that murdered tens of thousands of them in January. This means that the long war Iran has been waging on America, Israel and the West will continue. It will doom the world to years of more terrorism and the ever-present threat that it will be able to acquire the ability to inflict mass destruction on the Jewish state and moderate Arab countries that oppose it.

"As such, this agreement deserves to be vigorously debated. And, to his credit, Trump has offered to submit any deal to Congress for its approval.

"If so, that will make it equally clear that the political correlation of forces with respect to Iran is now very different from the situation in 2015 when Obama rammed his catastrophic JCPOA down the throats of an unwilling Congress and American people.

The JCPOA was unpopular

"It should be recalled that Obama’s Iran policy was deeply unpopular. A Pew Research Institute poll taken in September 2015 showed that the Iran deal was opposed by a large plurality of Americans, with 49% opposing it and only 21% in favor, with 30% saying they did not know (an unsurprising result given that most Americans pay little attention to most foreign-policy issues). And the more Americans knew about the agreement, the less they liked it, something indicated by the fact that opposition to the deal increased over the course of the year.

"Majorities in both Houses of Congress also opposed the JCPOA.

"It was only approved by a sleight-of-hand bargain in which Obama and Sen. Bob Corker (R-Tenn.), the feckless Republican who chaired the Senate Foreign Relations Committee, agreed that it would be put to a vote, which required a two-thirds majority to kill it. This was the opposite of the constitutional requirement for a two-thirds majority to pass a treaty. The House voted 269-162 (with 244 Republicans and 25 Democrats voting no) not to approve the JCPOA, with an equally large majority in the Senate also ready to vote against it. But since that fell short of a super-majority, Obama’s signature foreign-policy “achievement” that guaranteed that Iran would eventually get a nuclear weapon snuck through.

"Trump won’t have to resort to those kinds of legislative tricks.

"More to the point, the party opposed to the sitting president will play a very different role in 2026 than it did in 2015.

11 years makes a big difference

"A decade ago, Congressional Republicans were united against the Iran deal while Democrats were split on it. The GOP even went so far as to invite Israeli Prime Minister Benjamin Netanyahu to address a joint meeting of Congress that year, during which he gave an unprecedented address in which he urged its members to oppose Obama’s effort to enrich and empower an Iranian regime that threatened the United States as much as Israel.

"It was only by making support for the measure a litmus test of loyalty to himself that Obama was able to rally most Democrats behind a policy of appeasement that all but the most hard-core left-wingers in the party had opposed only a couple of years earlier. In 2015, there were still pro-Israel Democrats willing to speak up against Obama, even though most of those who had once claimed that title, like Sens. Chuck Schumer (D-N.Y.) and Corey Booker (D-N.J.), failed to maintain that stance when push came to shove.

"If anything, the current Democratic caucuses will be even more eager to terminate the war and appease Iran than they were then. While members of the opposition to the administration would seize on any pretext to thwart Trump, he can rely on them to support an end to the war. They will also be eager to do something that will be perceived as undermining Israel’s security.

"By contrast, the House and Senate GOP caucuses today are, as they were in 2015, almost uniformly pro-Israel and hawkish on Iran, with only outliers like lame-duck Rep. Thomas Massie (R-Ky.) and his fellow libertarian Sen. Rand Paul (R-Ky.), the rare exceptions to that rule.

What will Republicans do?

"That said, how many pro-Israel Republicans will vote against Trump on his Iran deal?

"Doing so will not only require the temerity to oppose a president who doesn’t lightly brook opposition and often gets even with those who do so, no matter how long it takes. It will also mean risking being portrayed as warmongers or advocates for a policy that would raise gas prices. It’s far from clear that even the most ardent supporters of a strong Israel and those most interested in stopping Iran would think it wise to try to thwart Trump from ending a deeply unpopular war, even if it is clearly in America’s best interests.

"Nor does it require much of an imagination to predict what Trump’s reaction would be to Netanyahu or any other Israeli or pro-Israel organization that advocated for Congress to turn down his version of Iran appeasement, as they did in 2015. It would make Obama’s spiteful attacks on those who opposed him on this issue seem quite tame by comparison.

"Thus, while Israel’s strategic position in the Middle East is far stronger than it was in 2015, in the United States, opposition to an appeasement of Iran on Trump’s part would be minimal. Those voices decrying a deal that trusted Iran to keep its word or which would depend on an unlikely decision by this president or one of his successors to resort to the use of force against the Islamist regime would find themselves largely alone, abandoned by Republican friends and mocked by Democratic foes.

Don’t blame Netanyahu

"There will be those who will blame this predicament on Netanyahu. His domestic opponents will claim that he depended too heavily on Trump’s friendship for Israel and that of the Republicans. And they will say he alienated Democrats.

"This is both untrue and deeply unfair. Whatever one might say about Netanyahu when it comes to navigating the political landscape of his country’s sole superpower ally, the current alignment has little or nothing to do with his unpopularity in the United States or his judgment.

"The drift by Democrats away from Israel is the result of the growing influence of toxic left-wing ideologies that falsely label it as a “white” oppressor state. Their willingness to accept and spread blood libels about Israel committing “genocide” in Gaza is not the product of Israeli behavior, but of the hijacking of the Democratic Party by antisemitic progressives. The prime minister had no chance of preserving a pro-Israel Democratic Party; the same would have been true of any Israeli leader.

"That means that Israel and its friends are in a position where they have no choice but to rely on pro-Israel Republicans to preserve the alliance. That worked wonderfully so long as Trump was behaving—as he has done during the first five-and-a-half years of his two terms—as the most pro-Israel president since the founding of the modern Jewish state. But with Trump adopting a more equivocal stand in which he may be waving the white flag on Iran and bristling with resentment at Netanyahu’s refusal to stop defending his citizens, that leaves supporters of Israel isolated in the United States on this issue.

"We must hope that it doesn’t come to that—and that Trump isn’t willing to go on deceiving himself and the American people about the dubious prospects for a policy that will preserve the despotic regime in Tehran and ensure that there will be more Middle East wars and bloodshed in the coming years.

"But if he is determined to stand by his own Iran deal, it won’t just signal that the aggressive presidency of the past 17 months is about to become a lame-duck administration, even before the outcome of the midterm elections is known. It will also mean that Israel and its friends will largely stand alone when it comes to the debate about this latest appeasement of the Islamist regime of Iran that Trump has given a new lease on life."

Jonathan S. Tobin is editor-in-chief of JNS

COVID Spike Coming This Summer

N C doctor anticipates summer COVID spike. Watch for these symptoms 

By Eva Flowe June 17, 2026 4:47 PM.

"There will be a spike in COVID-19 cases the summer of 2026, as there have been each summer, according to a North Carolina expert. 

"Dr. David Wohl, an infectious diseases expert with UNC Health, said there has been a spike in COVID-19 cases each summer since the virus first spread.

“Every summer, basically, of the pandemic, we’ve seen increases in cases in the summertime. I think that gets a little bit less attention than the wintertime spike that occurs,” Wohl said.

"Possible COVID-19 symptoms, according to the CDC, include: 

Fever or chills 

Cough 

Shortness of breath or difficulty breathing 

Sore throat 

Congestion or runny nose 

New loss of taste or smell 

Fatigue Muscle or body aches 

Headache 

Nausea or vomiting 

“I think what people don’t recognize is that COVID still does cause quite a bit of suffering,” Wohl said

Will new variants change the trend? 

"Wohl said there has been an increase in cases of XFG, an Omicron variant sometimes called Stratus.

“The wild landscape that the virus is circulating in has also changed, making it harder for the virus in many ways, because we have more and more immunity from repeated infections and from our vaccinations,” Wohl said. “It has to get through the maze of our immunity in order to infect more and more people, and that’s of course happening, so we’re putting pressure on the virus to evolve, and that’s going to happen no matter what.”

"The BA.3.2 variant of COVID-19 also garnered attention in 2025 and 2026. Like the insect, the Cicada COVID-19 variant has shown a pattern of disappearing and reappearing months later, The Charlotte Observer previously reported. 

"It was first identified in 2024, detected in someone travelling to the United States in 2025. NCDHHS had no updates to share about the Cicada variant with the Observer as of June 9.

“We definitely could see a little bit of an increase in that (Cicada variant) right now, but other than its sort of fanciful name, the attention to Cicada has been mostly just cautionary. It makes up a very small percentage of the COVID cases that we are detecting now,” Wohl said.

"The Cicada variant has the potential to reduce protection from a vaccine or previous infection because of the number of mutations. These mutations could make it more contagious, but NCDHHS said vaccination should still protect against the variant.

“We are in a different place with COVID-19 than we were earlier during the pandemic. A high percentage of the population has some protective immunity against COVID-19 and we have the tools, including vaccination, testing and treatment, to manage COVID-19 as we do for other respiratory illnesses,” NCDHHS Press Assistant James Werner wrote in an email.

"North Carolina no longer tracks COVID-19 variant data in specimens collected from patients."

Wednesday, June 17, 2026

The Art Of The Bad Deal

I watched some of the press conference today about the deal with Iran and was sorry I did.  Trump was more conciliatory towards Iran, the enemy, than he was to Israel, our ally.  I don't understand it. Who talked him into this? If anyone, ISRAEL should have been a full partner and asked to decide the terms, as they know more than anyone what Iran is capable of.

Any mention of money going to Iran should be deleted from the MOU. The only understanding Iran should have is that the Strait of Hormuz must be reopened now; that there cannot be any nuclear weapons or other weapons with which to wage war; and that the IRGC must disband.

And what about the Persian people in Iran? If the Islamic regime will remain, what happens to those people, 40,000+ of whom have already been slaughtered? Where is Reza Pahlavi now? 

I just hope Iran refuses to sign the actual agreement on Friday, and we can resume bombing. We never should have stopped.

And if Iran does sign? Then Trump will go down in history as another Neville Chamberlain. 

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David Horovitz at The Times of Israel, 6-17-26`

Trump’s deal is a catastrophic capitulation to Iran’s aggressors, leaves Israel vulnerable and constrained

In the US president’s reality-challenged view, Israel is an ingrate and a warmonger, while Iran’s mass-murdering leaders are ‘very rational.’ They are indeed all too rational, and he, clearly, is not

On March 2, the third day of the US-Israel war against Iran, US President Donald Trump’s special envoy Steve Witkoff gave an interview to Fox News in which he explained why the administration’s efforts to negotiate a deal with the regime in Tehran earlier in the year had failed.

He and Jared Kushner, Witkoff recalled, had been tasked with seeking an agreement under which Iran would halt its nuclear program, dismantle its ballistic missile program, cease its support for proxies, and eliminate its navy “so we can have freedom of the seas.

Far from entertaining a willingness to compromise, despite having been battered in the June 2025 12-day war, said Witkoff, the Iranian negotiators bragged that their obduracy and duplicity had been paying off. On the nuclear front, they gloated, they had amassed 460 kilograms of highly enriched uranium, which, Witkoff noted in his interview, could be turned into weapons-grade within 10 days.

“In that first meeting, both the Iranian negotiators said to us directly — with no shame — that they controlled 460 kilograms of 60% [enriched uranium] and that they’re aware that could make 11 nuclear bombs,” Witkoff recalled, aghast. The Iranians, he exclaimed, “were proud that they had evaded all sorts of oversight protocols to get to a place where they could deliver 11 nuclear bombs.”

They also claimed to have “an inalienable right” to enrich their nuclear fuel,” he noted, saying that he and Kushner had responded, robustly, by declaring “that the president feels we have the inalienable right to stop you dead in your tracks.”

Fast-forward three and a half months, and the US will on Friday formally sign a memorandum of understanding with Iran, already signed digitally long-distance, that resolves none of the goals of the war — none of the goals that Witkoff and Kushner attempted to resolve in their negotiated effort to avert the war.

According to a draft text obtained by The Times of Israel, CNN and Bloomberg on Wednesday, the 14-point MOU potentially grants the regime hundreds of billions of dollars — which it will doubtless utilize to help keep its restive population in line, to massively fund Hezbollah, Hamas and its other terrorist proxies, and to spend as needed on its nuclear and ballistic missile programs. (The White House said later Wednesday, without elaboration, that the draft text “does not reflect the language of the actual MOU.”)

The draft text provides for the reopening of the Strait of Hormuz — the vital waterway Iran seized and leveraged to push Trump into this deal — but with no long-term commitment by the regime to keep it open and toll-free.

And it pushes the entire subject of Iran’s rogue nuclear program into a 60-day negotiation period, during which the regime can be relied upon to be as uncompromising and dismissive as its negotiators were when facing Witkoff and Kushner in January.

Incredibly, the draft text of the MOU already rewards the regime for its intransigence: It states that Iran’s “nuclear needs” will be addressed in those 60 days; the US negotiators apparently could not even persuade the regime to include the words “peaceful” or “civilian,” to at least keep up the pretense that it has legitimate nuclear requirements.

During the 60 days, the text continues ridiculously, “Iran will maintain the status quo on its nuclear program.” What status quo would that be? The “status quo” under which Iran has run rings around the UN’s nuclear inspectors, to the point where, as its negotiators boasted to Witkoff, it amassed enough near-weapons-grade uranium for 11 nuclear bombs, an underground stockpile that survived the US Army’s B-2 bunker busters last June?

Last month, a senior Israeli military official warned that if the stockpile was not removed in the wake of the war, the campaign should be considered “one big failure.” And here we are. The official also warned that if that central goal was not met, Israel would need to launch another operation in Iran to achieve it. The draft text of the MOU would prevent Israel from doing so.

US sources have vouchsafed in recent days that CIA Director John Ratcliffe has warned Trump and his key officials that the regime is playing a double game. The CIA chief has reportedly explained that evidence gathered by US intelligence agencies raises serious doubts that Iran would be willing to make the nuclear concessions that the US wants in any final deal. “The intelligence reflects that the Iranian intentions are not in line with their commitments under the deal,” one US source told Axios. “Not in line with their commitments.” What magnificent understatement.

Of course, the Iranians have no intention of making any concessions that would strategically thwart their path to the bomb. Of course, they’re lying. They cheerfully told Witkoff in January that they’ve lied their way to their 60% stockpile.

The danger now, as realistically seen by Israel, is that they will use the 60-day “status quo” to accelerate toward nuclear breakout.

And yet, the same US administration negotiators who recoiled in horror at Iran’s obduracy in January have now yielded to it in June.

The deal manifestly empowers and finances a mass-murdering regime. It elevates the Islamic Republic to a regional powerhouse. It abandons the Iranian people to whom Trump promised that help was on its way.

And it directly endangers and constrains Israel, with terminology that binds Israel to a ceasefire it had no part in negotiating: “The Islamic Republic of Iran and the United States, together with their allies in the current war, declare upon the signing of this Memorandum of Understanding an immediate and permanent end to the war on all fronts, including Lebanon, and undertake that from now on they will not launch any hostile action against each other, and will refrain from the threat or use of force against each other (italics added).”

Trump asserted in remarks at the G7 summit on Tuesday that Israel should be showering him with gratitude, since it is only thanks to him that we were not already eliminated in an Iranian nuclear assault.

“If it weren’t for the United States of America — with me, because Obama was the opposite — Israel would not exist right now. Israel would have been blown off the face of the earth, 100 percent. And every smart person in Israel knows that,” he declared. “Without us, without the United States, there would be no Israel. Without me, there’d be no Israel, because no other president was willing to do what I did [in tackling Iran].” Iran, he said, was “two weeks away” from having a nuclear weapon.

But he has now struck a deal that fails to definitively close off Tehran’s practical capacity to complete its nuclear program, and removes US military leverage to deter it from doing so.

And that’s not all.

Let Syria take care of Hezbollah?!

Trump at the G7 also took public aim at Israel for its ostensibly disproportionate military action against Iran’s Hezbollah terror proxy in Lebanon.

Using the language of Israel’s bitterest critics, he charged that “Israel is fighting Hezbollah too long and too many people are being killed.” Elaborating, he snapped that “you don’t have to knock down an apartment house every time you’re looking for somebody. Because there are a lot of people in those apartment houses. And they’re not all Hezbollah, that I can tell you.”

So he wants both a shorter war, and also a less damaging war, to tackle a vast terrorist army, emplaced within civilian areas, directed by Iran to batter northern Israel these past weeks. A terrorist army dedicated, like Iran, to destroying Israel, and one that will invade northern Israel if given half a chance.

Warming to his reality-challenged theme, Trump prescribed that Israel “let Syria take care of Hezbollah. Because to be honest with you, I think they’d do a better job of doing it.” That would be Syria under Ahmed al-Sharaa, a former jihadist who had a $10 million US bounty on his head until December 2024, but over whom Trump has gushed since their first meeting in Riyadh last May. “Very capable,” he said of Sharaa on Tuesday. “And very good to me.”

In upside-down Trump world, Israel is the ingrate for not appreciating his heroic interventions on our behalf, and the illegitimate aggressor for seeking to complicate his submission to Tehran and its terror proxies. But the fact is that Trump gave up on the war when it became clear that winning it — first and foremost by thwarting Iran’s Hormuz takeover — would likely cost numerous American lives. That was, of course, a legitimate consideration, but one he should have weighed before starting the campaign. Facing enemies bent on its destruction, Israel knows it must put lives on the line to survive in this treacherous region.

Prime Minister Benjamin Netanyahu, frozen out of the negotiations, was needless to say not present at the G7 in France either — too toxic to the assembled notables, and perhaps also at risk of ICC-ordered arrest. Dissembling furiously, he is left trying to assert that the failed war was a success, falsely asserting on Monday night that the Iranian nuclear threat has been defused, that Iran’s economy has been devastated, and that the campaign against Iran “did not go wrong at all.” For his strenuous efforts to avoid a public showdown with Trump, the US president has repaid him by calling him “fucking crazy” and publicly declaring that “he has no fucking judgment.”

Iran’s leaders, in their current iteration, by contrast, “are very rational people” in Trumpland. “They were nice to deal with. They were strong people, smart people… They’re not radicalized and they’re, you know, looking to help their country,” he assured us all on Tuesday.

But, hey, even if they’re not, it turns out that he “never cared about regime change” anyway. This, from the president who, on February 28, as the US-Israel airstrikes began, told the Iranian public that, when the bombs stop, they need to “take over your government. It will be yours to take.

The 2026 US-Israel war against the Iranian regime was necessary. The Islamic Republic had been gunning down its own people in the tens of thousands. It was reconstituting its nuclear weapons program, reviving its ballistic missile production, rebuilding its terror proxies.

When the US and Israel struck, it had no hesitation in extorting the world via the Strait of Hormuz, and targeting anyone and anything it perceived to be vulnerable to attack, not only Israel (of course) but also its own regional neighbors, while lamenting that it did not (yet) have the capacity to strike directly back at the United States.

The war was lost through inadequate strategic planning by the US and Israel, and subsequent US presidential weakness. Trump’s capitulation is a betrayal of the Iranian citizenry. It will come back to bite America. It leaves Israel more vulnerable than before the war began, with a new US-Iran ceasefire agreement that aims to deny Israel the freedom to protect and defend itself.

The terms that the regime held out for and won indeed show its leaders to be “very rational people.” The same, with dire implications for the security of Israel and its people, cannot be said of Trump. 

Tuesday, June 16, 2026

Melanie Phillips, 6-16-26

Here's the latest column by Melanie Phillips. Unfortunately, I agree with her, although I'm more shocked by Trump's attacks on Israel than I am with the still unknown details of the deal with Iran.

I'm still trying to believe it's all a pre-planned ruse with Israel as before. As for Iran, they can do a lot of damage before the deal is signed on Friday -- if it is signed at all.

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Cyrus no more. The Trump administration's apparent naivety towards Iran is either imbecility or dissimulation

Melanie Phillips, Jun 16, 2026 

"The shock and distress in Israel are palpable. President Donald Trump’s apparent volte-face on Iran is being felt as an abandonment.

"Israelis are used to the indifference or hostility of American presidents. They managed to survive the malevolent manipulation of the Obama administration and the intimidation and threats of the Bidenites.

"But in Trump, here was a president who brought about something no-one had thought would happen — the United States and Israel fighting side by side to defeat one of the greatest evils in the world.

"On that terrible day of October 7 2023, when Israel was subjected to a barbaric invasion that exposed its weakness against a seven-front attempt by Iran to exterminate it with hundreds of thousands of missiles pointing straight at it, who would have thought that within a couple of years Iran and Hezbollah would be on their knees with their senior ranks taken out, their missile stocks radically depleted, Iran’s air defences obliterated and its nuclear weapons programme, which had been on the cusp of coming to murderous fruition, set back by years.

"It was Trump, to his enduring credit, who made that possible. Accordingly, he was hailed as a new Cyrus, the 6th century BCE Persian king who freed the Jews from captivity and helped rebuild the Temple in Jerusalem.

"Yet this week, the same Trump seemed to be pulling defeat from the jaws of victory. By signing an agreement with the very Iranian regime that he should have been continuing to destroy, he has instead thrown Tehran a lifeline; reduced America to a paper tiger; accordingly put a spring in the step of Russia, China and North Korea, as well as emboldening Islamists seeking to destroy the west — and having undermined Israel’s security, aggressively turned on Israel for presuming to defend itself.

"The US not only excluded Israel from discussions leading up to the Memorandum of Understanding (MOU) but also, while currently keeping its terms secret from the world, has refused even to show them to the Jewish state.

"That’s Israel, America’s close ally and indispensable “unsinkable aircraft carrier;” Israel, which Iran is making every effort to wipe off the face of the earth; Israel, whose soldiers have been dying not just to save their own country but in defence of an America that refuses to put its own troops in danger but is all too happy for Israelis to die in defence of itself and the free world.

"Contrary to much misreporting, the MOU is not a deal that ends the war. It’s rather a framework for negotiations during a 60-day ceasefire. In a blizzard of claims and counter-claims, we don’t know what its terms are. But what’s undeniable is that Trump has chosen this moment, when the Iranian regime was weakening by the day, to take his knee off its windpipe by lifting the US blockade of Iranian ships. Going into the 60-day negotiation, he has thus chosen to make Iran stronger and the US weaker.

"Worse, there are suspicions that he will allow money to start flowing into Tehran’s coffers. Vice-president JD Vance has repeatedly stated that Iran won’t benefit unless it complies with US demands. “The agreement says they are not getting a single dime of American money,” Vance insisted on Fox News. But the money in question isn’t America’s but Iran’s own frozen assets.

"Israeli TV’s Channel 14 reported a claim that the Islamic Revolutionary Guards Corps that runs Iran had no intention of honoring the agreement. IRGC Commander Ahmad Vahidi was quoted as saying:

"Let’s take all the money right now, and then we’ll do whatever we want."

"The CIA seems have borne out this bad faith. CIA Director John Ratcliffe reportedly told Trump and other senior officials that intelligence gained by the US raised serious doubts about Iran’s willingness to make the nuclear concessions that America is seeking in any final deal.

"While we don’t know the terms of the MOU, statements by Trump and Vance are themselves causing great concern.

"The US originally said Iran must not enrich uranium, period. Yet Trump has told The New York Times that Iran would be permitted to enrich uranium at a low level and never for military purposes. But how low? It’s possible to get quite easily from some relatively low levels to weapons-grade enrichment in a short space of time.

"Trump has said repeatedly that Iran will never get a nuclear weapon, and if it tried it would suffer “unbelievable consequences”.

"But he has also said:

"We are talking to them about a 15 to 20-year ban."

"Well, which is it? This sounds exactly like the 2015 Obama deal which, with the US declaring then too that Iran would “never get a nuclear weapon,” explicitly green-lit an Iranian bomb after just a few years’ delay.

"At the same time, Trump says Iran has agreed to “never have a nuclear weapon”. If so, why then does it need a 15 to 20-year ban? And since the Iranians have always lied through their teeth about this, how could anyone believe a word they ever say?

"The naivety being expressed by both Trump and Vance borders on imbecility. Or is it cynical dissimulation? Vance says the big difference from the Obama deal is that Iran will be required to verify its commitment not to build a nuclear weapon. But the Obama deal also requited verification. Tehran merely hid what it was doing in sites unknown to the nuclear inspectors or from which they were barred.

"At the G7 summit, Trump said the Iranian regime had changed because so many former leaders had been killed. The people in charge now were “very rational” people. He said:

"They were nice to deal with. They were strong people, smart people. I think actually they’re smarter than the first and second group, but they’re not radicalised and they’re, you know, looking to help their country."

"But the Iranians charming the apparently witless US team are obviously telling the Americans what they want to hear — such as, according to Trump, that they now realise their four decades of waging war on the free world had been a mistake. How can any sentient being believe such patent nonsense? Iran is still being run by the IRGC who are no less fanatical than the regime has ever been — maybe even more so.

"Meanwhile, on Monday night Hezbollah broke its own ceasefire for the umpteenth time by firing numerous rockets toward IDF soldiers in Lebanon. Defeating Hezbollah is absolutely critical for Israel, whose north is at risk of becoming depopulated under the never-ending bombardments from Hezbollah.

"But this proxy army is vital for Iran. So it’s demanding that the MOU ceasefire must include Lebanon. And although it does not, Trump is now appallingly taking Iran’s side by pressuring Israel to stop fighting there to keep his “deal” on track.

"His remarks on this at the G7 summit in France were deeply shocking. He said:

"Israel’s fighting Hezbollah for too long, and too many people are being killed. You don’t have to knock down an apartment house every time you’re looking for somebody because there’s a lot of people in those apartment houses and they’re not all Hezbollah, that I can tell you..

"I’m not happy with the way Israel has handled themselves with Lebanon and with Hezbollah. They should have been able to do the job faster. It just goes on forever. And when that happens, it throws a negative light on the big deal, and that’s the deal with Iran…

"I suggested to Israel to let Syria take care of Hezbollah, Because to be honest with you, I think they’d do a better job of doing it."

"And he said of Syria’s president Ahmed al-Sharaa:

"He’s very capable. And he’s been very good for me. He’s protected everything that I’ve asked for. If Israel can’t do the job without killing everyone else, he’ll do the job. Syria will do the job…

"Without the United States, there would be no Israel. Without me, there would be no Israel — because no other president was willing to do what I did. I had a great relationship with Bibi, but now Bibi has to be more responsible with respect to Lebanon.

"Thus Trump ignored the fact that, just like Hamas in Gaza, Hezbollah situates its machinery of war in and around civilian homes; and he would deliver Lebanon to al Sharaa, who is ISIS in a suit — all the while denigrating Israel’s formidable challenge in Lebanon, its skill in dealing with it, and the terrible sacrifice of its soldiers’ lives it is being forced to make there.

"So Israel now faces an excruciating choice — between abandoning its northern citizens to Hezbollah attacks, and risking a vindictive Trump cutting off the military support necessary to keep itself alive.

"Americans may not realise it, but Trump’s lethal fantasy that he has transformed the genocidal fanatics of Tehran into people whose highest goal now is to emulate the prosperous burghers of Switzerland, where Friday’s MOU signing ceremony is to take place, is putting America itself at grave risk.

"As for those Israelis who allowed themselves to put their trust in this most capricious of princes, they forgot the basic lesson of their history — that the Jews are always alone."

FBI Thwarted a Major Terrorist Attack

Thank goodness for this FBI.  And thanks to a family member of one of the plotters; he saw something and said something.

These evil plotters deserve to be publicly perp-walked to serious prison time. 

Where'd  they get the idea from -- the Democrats'  and other groups' constant anti-Trump, anti-Israel, anti-capitalism rhetoric, perhaps? "Toning it down", as VP Vance suggests, is not going to work, because it hasn't worked yet despite years of anti-Trump assassination attempts, bombings, fires, and riots. 

--------------------------------

Fox News 6-16-26

FBI disrupts alleged explosive-drone plot targeting White House UFC event, officials say.

Signal chats allegedly revealed 23 people discussing pre-operational activity 

"FIRST ON FOX: The FBI and its law enforcement partners disrupted an alleged plot targeting this weekend’s UFC Freedom 250 event in Washington, D.C., officials told Fox News Digital.

"Five people were in custody as of Monday, and investigators identified 23 people as part of a potential network of plotters. The alleged plan involved using explosive-laden drones to hit buildings near the event, force a mass evacuation and steer crowds toward a pre-staged sniper team, officials said.

"A "second wave" was then allegedly planned to storm the White House gate, according to officials.

"The FBI first learned of the threat on June 10 and worked with partners to secure probable cause for an arrest in Cincinnati, where one suspect was taken into custody. Court documents identified the suspect as 19-year-old Tycen Proper. 

"Two others, identified as Bryan Omar Roa and Michael Alan Thomas, were arrested in California for alleged involvement in the plot. Both men were charged with conspiracy to commit murder. They appeared in court on Monday in Riverside.

"Other suspects were arrested in Missouri and Nebraska. Multiple sources told Fox News that those in custody are American citizens, and a foreign nexus was not involved.

"According to a criminal complaint, Proper allegedly spent $3,000 of his "graduation money" to purchase "lots of" ammunition, guns, extra magazines and other items for the alleged attack

"Authorities estimated that several boxes of ammunition that Proper had allegedly acquired contained thousands of rounds. It is also alleged that Proper acquired an AR-style rifle, a bullpup rifle painted with the American flag and two plate carriers with AR-style magazines. His family voluntarily turned over the equipment to law enforcement.

"His father told officers that Proper had quit his job to meet up with people he had met online to conduct "missions" and "recons," according to the complaint.

"The U.S. Secret Service said it "worked closely" with the FBI during the investigation.

"In the days leading up to this weekend, our special agents, mission support personnel, and technical security teams worked around the clock to identify those responsible and hold them accountable," Secret Service Director Sean Curran said in a statement. "Equally important to our protective mission is ensuring accountability through the justice system. To that end, our formal comments regarding the specifics of this case will be made through court filings."

"Investigators later uncovered Signal chats in which multiple people allegedly discussed attacking the UFC event. An initial review of one suspect’s iPhone identified at least 23 Signal users discussing pre-operational activity, officials said.

"Some of those involved allegedly planned to travel to Fredericksburg, Virginia, on June 12 or 13 to prepare for the attack.

"One suspect allegedly told investigators the goal was to target "capitalist elites," "billionaires" or politicians who received donations from the American Israel Public Affairs Committee.

"The investigation stretched across at least 12 FBI field offices.

"FBI Director Kash Patel credited the FBI, the Department of Justice (DOJ) and law enforcement partners with acting quickly across multiple states to prevent the alleged attack.

"Thanks to the rapid action of this FBI, our partners, and the Department of Justice in a multi-state operation, multiple individuals are now in custody and allegedly planned attacks were stopped cold," Patel said in a statement to Fox News Digital.

"Patel said the operation showed the FBI’s ability to respond quickly when threats emerge.

"While the result represented the best of investigative work, it was also nothing out of the ordinary for this law enforcement team," Patel said. "We are built to detect, respond to, and bring to justice those who threaten the lives of American citizens — particularly during large gatherings like the historic UFC 250 fight. That’s exactly what we did here."

"I want to thank our great agents and partners, this work remains ongoing, and we will continue to update the public as permitted," Patel added.

"The alleged plot targeted UFC Freedom 250, a high-profile White House event held on the South Lawn as part of President Donald Trump's 80th birthday weekend.

"The event drew an estimated 4,300 attendees, including about 1,200 active-duty service members, as 14 fighters from around the world competed inside a wire-mesh cage Sunday night.

"Reacting to the news on "FOX & Friends" Tuesday, Vice President JD Vance called it "very, very dark stuff."

"This is what happens when people turn the rhetoric up so loud that disagreeing with somebody is a cause for violence," Vance said. "We got to tell everybody to tone it down."

"Everybody has a role to cut this stuff out," Vance continued. "But I think a lot of my Democratic colleagues in Washington have got to look themselves in the mirror and say, why is so much of this political violence coming from our side of the spectrum?"

 "The alleged plot comes amid a growing series of threats and security incidents involving Trump and senior administration officials, fueling heightened concerns about political violence."

Your Local Epidemiologist: The Dose, 6-16-26

Joy is contagious. Also: mosquitos, infant botulism, H5N1, peak tick season, and more.
The Dose 
Katelyn Jetelina, Jun 16, 2026

I’m not a big basketball fan, but boy, the sound of Manhattan at the final buzzer of the NBA Finals was electric in every video I came across: cheering, weeping, horns honking, singing, hugging, cigars being lit, an utter unselfconsciousness, pure and absolute jubilation. It gave me goosebumps. It’s a reminder that joy is contagious. Congratulations, New Yorkers, and thank you for the reminder of the value of community and shared joy. More of that, please.

Speaking of shared joy, the World Cup has officially kicked off, and we are here with what the health data show. We’re also at peak tick season, and mosquitoes and infant botulism have entered the chat. Other low-risk but high-consequence things are happening, including bird flu heating up among cows again.

And pediatricians are getting bombarded with vaccine questions. We answer the latest and update a resource for you.

Here’s what’s going on and, most importantly, what it means for you.


Disease “weather” report

We are at peak tick season

Across much of the U.S., we’re in the heart of tick season. After starting earlier than usual, it’s now tracking close to previous years. I’m hopeful we’ll see activity taper off over the coming weeks.

Source: CDC; Annotated by YLE

What this means for you: It’s still important to enjoy the outdoors, so prevention is the name of the game. Use an EPA-approved repellent, wear long pants when possible, and do a quick tick check afterward. The vast majority of ticks don’t carry diseases, but regardless, the sooner a tick is removed, the lower the risk of transmission.

Mosquito season is here

Mosquito season is ramping up across much of the country. We can expect mosquito-borne diseases to peak in August or September.

Why? Mosquitos are cold-blooded, so transmission is a bit like a chemistry experiment. If it’s too cold (below ~16°C or ~60°F), the mosquito life cycle slows down too much to spread disease. Closer to the “magic temperature” of ~25°C / ~77°F, mosquitoes are happier and diseases spread a little more easily from mosquito to human.

West Nile is the leading cause of mosquito-borne disease in the U.S. It is a fairly new disease—25 years ago, we didn’t have it around. But it is very rare. So far this year, we’ve seen only 13 cases of West Nile. (In June 2025, we had 62 total and August had the most cases at 958)

What this means for you: Your risk depends on geography and other factors, including older age. As mosquito populations grow, it’s worth dusting off the bug spray and clearing standing water around your home.

Low risk to you, but disease of high (and potentially) consequence

Several outbreaks are on my radar, but all remain very low risk to the general U.S. public:

  • Another infant botulism outbreak tied to baby formula. Nara Organics has recalled its organic formula, sold nationwide at Target, after three babies between 2 and 5 months became critically ill in CA, PA, and WA. Like the ByHeart recall last fall, it’s a niche product (under 1% of supply). What makes this one sting a little more: ByHeart had actually pointed parents to Nara as the safe alternative after their own recall. Regardless, it’s a reminder of how much we depend on the systems around us working.

  • Ebola cases in Africa have climbed to 808, including one of the largest single-day jumps over the weekend. The cumulative total has already surpassed what the two biggest prior outbreaks reached at the same point in their first 100 days. This is a sign this one is likely to grow very large. If you're traveling to Africa (or have patients traveling), check out the YLE decision tree here.

Cumulative Ebola cases in first 100 days of outbreak declaration. Markers are values from WHO/CDC/ECDC situation reports. Figure by Your Local Epidemiologist
  • Bird flu (H5N1). After months of relative quiet, the USDA reports a sharp jump in infected dairy herds: in the past 30 days, 45 tested positive in Idaho, 2 in Utah, and 1 in Texas. We’re not at 2024 levels, but this is more than we’ve seen in a while.

H5N1 dairy herds. Purple: updated figure with USDA numbers since CDC figure has only been updated since June 3. Source: CDC and USDA.

Healthy Cup

The World Cup has officially begun, and the good news is that there have been no significant health events so far. Overall health risks remain low, but we’re watching three signals:

  1. Heat. On opening day, Fan Fests in the Texas area saw nearly 100 fans fall ill from the heat, some requiring hospitalization. This is concerning because for every reported heat illness, many more sit just short of emergency, like dehydration and falls, cardiac problems, kidney stress, and mental status changes in elders. The “count” (22 out of ~30,000 attendees) underestimates the harm. Keep cool; drink water; know that alcohol and drugs mask heat injury symptoms, and common medications increase heat vulnerability. Go here to see your heat risk this week.

  2. Measles. A few outbreaks are happening in the background, but two “sparks” sit particularly close to World Cup events, and we need to ensure they don't turn into wildfires:

    1. Wastewater monitoring has detected a signal in Chester City, Delaware County (15 miles from Philadelphia Stadium).

    2. One case among an unvaccinated resident in Santa Clara County, California, with recent international travel and community exposure, including at the airport.

  3. What other things are people worried about? The YLE weekly survey of World Cup goers started last week. No major health rumors are surfacing yet (only 13% have heard any), but there’s concern about traffic and transportation accidents, as well as ICE.

Figure from Your Local Epidemiologist

Good news

We can always use it. Three today:

  • FDA clears a screwworm treatment for dogs and cats. The FDA authorized emergency use of generic nitenpyram tablets for infected pets, expected to kill most larvae within hours. New World screwworm numbers continue to climb, with 12 animal cases across 7 counties. This medication is not preventative but an important new tool if an infection occurs—and more will be happening given how quickly this thing spreads.

New World screwworm detections by county. Figure from a dashboard created by Genompic Epi.
  • A new sunscreen ingredient, the first in over two decades. The FDA has approved bemotrizinol, used for years in Europe, Asia, and Australia, where it’s prized for strong, stable protection against both UVA and UVB. The approval spotlights a U.S. quirk: because sunscreens are regulated as drugs here, new ingredients can take years or decades to reach consumers. Products could appear later this year, though wide availability will take time. Read more about sunscreen at the YLE deep dive here.

  • A lab-grown heart-muscle patch. Researchers implanted a stem cell-derived patch of heart muscle onto the failing hearts of 16 patients with advanced heart failure. The effect was real but modest, more of a signal of progress. Read more here.


Question grab bag

“This week I have encountered several patients saying “vaccines are only studied for 5 days.” Can you update your 12 questions about vaccines handout to address this succinctly? It would be very much appreciated. - A tired pediatrician.”

This is a common rumor. That figure comes from a line in the package insert describing the short window when vaccine trial participants fill out a daily diary card (see below for an example). But that card is only tracking the expected, short-lived reactions to a vaccine (sore arm, redness, fever, fussiness), which are caused by the immune response itself and reliably fade within a few days. Symptoms that persist longer usually point to a different cause, like an unrelated infection picked up around the same time, so that brief window is all the diary card needs to cover.

Chart from Appendix 3 here has an example showing what these look like.

But vaccine monitoring doesn’t stop there. The same trials track other health events for months to years, recorded as they happen rather than on a checklist. And for routine childhood vaccines, those original trials are now just the starting point: we have real-world safety data on hundreds of millions of children across decades, consistently showing that the benefits far outweigh the risks.

We’ve updated the FAQs for paid subscribers, with the latest is available below. Thank you for all your effort, and all clinical care teams on the front line. 

"Not Interested In Working For a Jew"

I haven't been able to get this brazenly antisemitic incident out of my mind, partly because something similar happened to my father when I was a kid.  After speaking with a potential customer over the phone, my father was informed by the boss that the customer had then complained to him that he didn't want to work with a Jew. So my father was told to change his name and use a non-Jewish-sounding last name from now on instead.

----------------

Contrast Franco's unapologetic hatred to the Einhorns' regret at exposing him. They are model young Jewish businessmen, and I hope their startup thrives.

This hateful Cornell student should be blacklisted and not get any interviews or jobs with any decent employers, Jewish or not.  

Of course, the anti-Jewish campus activists and anti-Israel rioters would be thrilled to have such a Jew-hater working for them, and he is probably going to be extolled as some sort of hero. The antisemites deserve him. 

---------------------------------------------- 

New York Post 6-13-26 

Antisemitic Cornell student turns down interview because he's 'not interested in working for a Jew'

"A Cornell University student who applied for a summer internship with a Jewish-owned NYC startup rejected the opportunity with a hateful message: ‘Not interested in working for a Jew,” the shocked CEO posted on X.

"Austin Franco put his antisemitism on full display when he passed up an interview with VryfID because its co-founders Gabe and Aiden Einhorn are proudly Jewish. 

"Franco, 19, delivered the message to both brothers via job board site Handshake after applying for a summer role at the company, which pairs renters with landlords and verifies their identities to prevent fraud. 

A picture of Austin Franco.

Austin Franco, 19, declined a job interview because he didn’t “want to work for a Jew.” Linkedin / Austin Franco

The two brothers posed together wearing suits.

Aiden, left, and Gabe, right, started the company together in the summer of 2025. Courtesy of Gabe Einhorn

"The Einhorns reviewed Franco’s application and he was being considered for an internship with VryfID’s growth team, which is tasked with attracting renters to the company.

“Sad world,” Gabe, 24, wrote on X Monday along with a screenshot of Franco’s jaw-dropping eight-word response to trying to schedule a Zoom call: “Not interested in working for a Jew. Thanks.” 

"Gabe Einhorn told The Post he felt obligated to share the message to raise awareness of growing antisemitism. He blacked out Franco’s name out of graciousness, but commenters quickly revealed his identity. 

“I felt bad exposing him because I thought he could have made a mistake and he really doesn’t believe this wholeheartedly,” Gabe said. 

"But the Ivy Leaguer soon made it clear that he meant every word of what he wrote. 

The student who hails from Virginia doubled down in an X post shared the next day.

A head shot of Gabe Einhorn.

VryfID CEO Gabe Einhorn, 24, co-founded the company with his brother last summer. Linkedin / Gabe Einhorn

My experiences with Jews have not been pleasant, both in person and online. This is not to say I haven’t had positive experiences, but on the aggregate that is not the case,” Franco wrote.

"Cornell — where Franco studies industrial and labor relations, according to his since-deleted LinkedIn profile — is investigating the incident. He sent the disgraceful message on Monday, about a month after Cornell’s semester ended.

“Cornell condemns antisemitism and all forms of hatred and discrimination in the strongest possible terms,” a university spokeswoman told The Post.

"Gabe and his younger brother Aiden, a 22-year-old NYU business student, launched VryfID in the summer of 2025.  

A photo of his LinkedIn profile.

Franco attends Cornell and is studying labor relations, according to his since-deleted LinkedIn.

“Instead of renters struggling to search for apartments and getting rejected, we have them sign up, pay $20 to get verified. Then we actually bring them apartments that they actually qualify for,” Gabe explained to The Post. 

“For landlords, it helps them fill up their units and brings them the right tenants.”

"Aside from content centered around the NYC rental market, Gabe, who wears a kippah, often speaks about his faith across his growing social media platforms. 

“I’ve seen some terrible things across the board — antisemitic things and just terrible things in general,” Gabe said, adding that he had about five death threats just on Facebook the last time he checked. 

A photo of the post.

Franco doubled down on his hatred in a response posted on X.

“People just like to spread hate across social media because they’re anonymous and they have no repercussions.”

"The hateful message has left the brothers stunned. 

“Me and my brother kind of looked at each other like, ‘What?’ We never really experienced [antisemitism] this directly,” Gabe said.

“The whole thing was just very shocking and uncalled for.”

"Franco did not return requests for comment. His father, Alexander, a patent attorney, declined to comment."

Monday, June 15, 2026

Dr Ruth Report 6-14-26

Here's the latest comprehensive medical report from Dr. Ruth Ann Crystal. There's so much to learn from her newsletters!

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Dr. Ruth Report, 6/14/26
Ruth Ann Crystal MD, Jun 15, 2026 

COVID levels in wastewater are at their lowest since 2021, except for a few hot spots in Ohio, Idaho, Florida and Maine. We will have to wait and see if the World Cup games will have any effect on COVID levels, or on measles cases for that matter.

Using Biobot and CDC data through June 6, Mike Hoerger estimated that about every 1 in 269 people was currently infected with COVID, with 182,000 new COVID cases each day in the United States.

This week, research shows autoantibodies in kids after COVID infection, decreased glucose metabolism in the brains of people with Long COVID, an ultrasound patch that can continuously monitor the fetus in pregnancy, inhaled insulin for kids with diabetes, and much more.

Pediatrics

Antibody repertoire associated with clinically diverse presentations of pediatric SARS-CoV-2 infection | Nature

Long-Term Outcomes of Multisystem Inflammatory Syndrome in Children (MIS-C) up to 4.5 Years After COVID-19 | Pediatrics (AAP)

  • Montefiore Health System researchers tracked 14,363 children and adolescents and found that MIS-C was associated with elevated risks of cardiac, pulmonary, gastrointestinal, neurological, renal, and blood pressure disorders persisting as long as 4.5 years after COVID infection. These findings underscore that the health burden of MIS-C extends well beyond the acute phase of illness. “Structured long-term follow-up, including routine blood pressure monitoring, neurological and mental-health screening, and cardiovascular and renal surveillance, with coordinated multidisciplinary care is warranted.”

Made with Canva and ChatGPT

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Vaccines

Menstrual cycle phase and its association with COVID-19 vaccine outcomes among period tracking app users | npj Women’s Health

  • London scientists, in collaboration with the Clue app, analyzed data from 1,474 women and found that receiving a COVID vaccine during the follicular (estrogen producing) phase of the menstrual cycle was associated with 35% greater odds of side effects as compared to the luteal (progesterone producing) phase, with longer lasting protection. “Median time to COVID infection was 35 days longer following follicular-phase vaccination (200 vs 165 days, p = 0.05), though infection numbers were limited,” and more studies are needed.

Sustained antigen-specific CD8+ T cell immunity post–mRNA booster requires notch pathway activation | Journal of Immunology

  • Japanese researchers followed 141 people after a third Pfizer COVID-19 booster and tracked spike-specific CD8+ killer T cells for six months. People who maintained strong T cell responses showed higher activity of the Notch signaling pathway, while those whose responses waned did not. Blocking Notch signaling in the lab prevented CD8+ T cells from expanding after re-exposure to spike protein. These findings suggest that Notch signaling helps sustain long-term killer T cell immunity after mRNA vaccination and may be a target for improving future vaccines.

Long COVID

Persistent Cerebral 18-FDG PET Changes in Patients With Long COVID Presenting With Fatigue and Post Exertional Malaise | J of Primary Care & Community Health

  • Scientists from Mayo Clinic examined 40 Long COVID patients experiencing fatigue and post-exertional malaise (PEM) and found measurably decreased cerebral glucose metabolism via 18F FDG PET imaging, concentrated in sensorimotor and visual brain regions. This pattern of reduced brain energy use persisted for at least two years after the initial COVID infection in patients with fatigue and PEM.

Figure 2. Representative 18F-FDG PET scan for a patient with Long COVID showing cerebral hypometabolism.

  • The bottom panel shows “near global hypometabolism particularly pronounced in the occipital lobes, correlating with the participant’s symptoms of cognitive dysfunction and fatigue with post exertional malaise.”

From: https://journals.sagepub.com/doi/10.1177/21501319261458748

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Single-cell profiling of innate and adaptive immune dysregulation in Long COVID | BioRxiV

  • Emory University researchers analyzed single-cell profiling on 156,478 peripheral blood mononuclear cells (PBMCs) from 20 Long COVID (LC) patients and 18 recovered controls (RC) and found that Long COVID patients show persistent immune cell activation consistent with ongoing viral antigen exposure. B cells remained in an activated state, T cells displayed markers of exhaustion, and NK cells lost normal function, collectively pointing to a system that cannot stand down from fighting an infection that may still be present in some form.

Beyond brain fog: viral proteins as convergent drivers of neuroinflammation and proteinopathy | Current Opinion in Virology

  • A new review from the University of Veterinary Medicine Hannover proposes that viral proteins persist after viral infections. These viral protein fragments can act as neurotoxins and can activate TLR4 and TLR2 toll-like receptors on glial cells which triggers neuroinflammation even when live virus is absent from the nervous system. The inflammatory cytokines made by glia cells and astrocytes can also activate tau and alpha-synuclein proteins to accumulate in the brain. Tau protein is associated with Alzheimer’s disease and alpha-synuclein with Parkinson’s disease and Lewy body dementia. This offers a concrete molecular pathway connecting post-infectious illness, including Long COVID, to lasting cognitive (brain fog) and neurological symptoms.

From: https://www.sciencedirect.com/science/article/pii/S1879625726000519#fig0005

Intracellular microbial shifts during COVID-19 infection and longitudinal recovery revealed by single-cell RNA sequencing | iScience

  • Scientists in India performed single-cell RNA sequencing of 191,417 peripheral blood mononuclear cells (PBMCs) from 57 individuals (9 healthy, 24 Omicron-infected, 16 recently recovered, 8 Long-recovered) and discovered that SARS-CoV-2 infection altered the microbial communities residing inside immune cells, with opportunistic bacteria accumulating specifically within T cells and platelets. Over the course of extended recovery, the intracellular microbial composition in these individuals gradually shifted back toward the patterns observed in healthy people.

Salivary microRNA Profiling of Long COVID Subjects Reveals Host-Encoded Regulators of Inflammation and Viral Persistence | BioRxiV

  • Researchers from the University of Illinois Chicago studied 30 participants and found that Long COVID patients with periodontitis had widespread depletion of salivary microRNAs that ordinarily suppress NFκB driven inflammation and are capable of binding SARS-CoV-2 RNA. When those microRNAs were reintroduced in cell experiments, both inflammatory signaling and viral gene activity measurably declined.

COVID‐19 as a Potential Trigger for Tuberculosis: Insights From a Large‐Scale Japanese Insurance Database Analysis | J of Family and General Medicine

  • A retrospective cohort study from Japan of over 6 million people shows that COVID infection is associated with a 4x risk of needing Tuberculosis treatment. In those who had prior tuberculosis, risk was 14.7x higher after COVID infection, showing that COVID infection may increase the risk of Tuberculosis reactivation.

A more than fourfold increased risk of active TB treatment initiation following COVID-19.

From: https://onlinelibrary.wiley.com/doi/10.1002/jgf2.70139

Immunothrombosis in hospitalized COVID-19 patients identified by multiomics profiling and linked to postacute complications | iScience

  • A group from Latvia followed 81 hospitalized COVID patients and found that blood drawn three months after severe infection continued to show measurable abnormalities in platelets, the complement system, and vascular function in 46 people with Long COVID. These persistent immunothrombosis signatures suggest that clotting related disruptions in severe acute COVID infection can leave a lasting biological imprint in Long COVID.

Immunoadsorption Versus Sham Treatment for Post-COVID Syndrome: A Randomised Sham-Controlled Crossover Trial | Lancet Regional Europe

  • Researchers from Mainz, Germany tested immunoadsorption in 40 Long COVID patients to determine whether removing GPCR autoantibodies from the bloodstream would relieve Long COVID symptoms, but outcomes did not improve compared to the sham procedure. Immunoadsorption also produced adverse events at a higher rate than the control condition.

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Measles

CDC Measles updates (on Wed.):

  • As of June 11, 2026, 2,073 confirmed measles cases were reported in the United States in 2026.

John Hopkins US Measles Tracker

  • There have been 86 new measles cases, mostly in Utah and Virginia.

Other news

Fetal monitoring for high-risk pregnancies using a wearable ultrasound patch | Nature Biotechnology

  • This may be a game changer for obstetrics. UC San Diego researchers developed a wearable ultrasound patch (UPatch) for continuous fetal ultrasound monitoring. Tested on 62 pregnancies, the UPatch matched handheld clinical ultrasound readings and tracked fetal blood flow in real time autonomously without a sonographer. Continuous UPatch ultrasound monitoring in 52 pregnant women successfully stratified high risk obstetrical conditions including preeclampsia, gestational diabetes, and fetal growth abnormalities.

From: https://www.nature.com/articles/s41587-026-03140-1

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FDA Approves Inhaled Insulin for Children, Adolescents With Diabetes | AJMC

  • The FDA approved Afrezza (inhaled insulin human) for children and adolescents ages 6 and older with type 1 or type 2 diabetes, making it the first needle-free mealtime insulin option for pediatric patients. The phase 3 INHALE-1 trial showed no significant pulmonary safety signals, and treatment satisfaction was higher in the inhaled insulin group for both patients and parents.

Microbiota-driven gut-brain signaling underlies antidepressant effects of a GLP-1 analog | Cell

  • Chinese scientists showed that liraglutide reduced depressive behavior in mice through a pathway that bypasses its known GLP-1 receptor, instead operating through changes in gut bacteria. The drug selectively increased Lactobacillus delbrueckii populations in the gut, which in turn increased endocannabinoid 2-arachidonoylglycerol (2-AG), which then suppressed stress-related overactivation in brain circuits related to depression.

Gut microbiota-derived short-chain fatty acids (SCFAs): immunomodulatory effects and therapeutic potential in infections | Clinical Microbiology Reviews

  • A new review examines how short-chain fatty acids (SFCAs), especially butyrate, propionate, and acetate, affect immune responses to bacterial, viral, and fungal infections. Gut bacteria produce SFCAs when they break down dietary fiber. SCFAs and SCFA-producing bacteria may support treatment of infections by strengthening the gut barrier, calming excess inflammation, and boosting pathogen clearance, but their effects vary depending on the microorganism and the SCFA concentration.

Fig 3 The regulatory effects of SCFAs on the intestinal barrier, host immunity, and distant organs.

From Fig 5: Interactions between SCFAs and viruses.

Made with Canva, based on https://journals.asm.org/doi/10.1128/cmr.00368-25

Interleukin-10 Autoantibodies and HLA-DRB1*01:03 in Inflammatory Bowel Disease | NEJM

  • Interleukin-10 (IL-10) is an important anti-inflammatory cytokine. Researchers in England discovered anti-IL-10 autoantibodies in 3.5% of 4,909 Inflammatory Bowel Disease (IBD) patients studied. IL-10 autoantibodies were highly enriched in people with HLA-DRB1*01:03, with odds ratios of 24.7x - 50.0x found across two large cohorts. High anti-IL-10 titers were associated with exaggerated proinflammatory cytokine release. The findings reframe IBD as a group of mechanistically distinct diseases and open a path toward targeted anti-autoantibody therapy in a subset of patients.

Explainer article can be found here:

Autoantibodies against Cytokines — From Infection to Inflammation | NEJM

I’m a Tech Expert. Here’s How I Prep My Devices for an International Trip. | NY Times (Article can also can be found at https://archive.is/Jr0y5)

  • Heading overseas this summer? A tech journalist’s pre-trip checklist: check your carrier’s international plan, grab an eSIM for cheap local data, download offline maps and translation tools, back up your itinerary and passport, and pack a universal travel adapter. He also recommends that before flying home, disable biometric unlock and consider hiding your social apps to protect your privacy at customs.

A former teacher reunited with students decades after inviting them to watch the 2024 solar eclipse together | Today

  • Retired Rochester science teacher Patrick Moriarty reunited with over 100 former students for a solar eclipse watch party he had planned 46 years earlier. In 1978, he told his 9th graders to mark April 8, 2024 on their calendars. He also extended the invitation to students in subsequent years. Decades later, his former students came from across the country, some with gray hair like him, to watch the solar eclipse with their favorite teacher.

Mr. Moriarty and some of his former students
Photo: Caitlin Moriarty Hynick

Have a great week,

Ruth Ann Crystal MD