Tuesday, June 16, 2026

Melanie Phillips, 6-16-26

Here's the latest column by Melanie Phillips. Unfortunately, I agree with her, although I'm more shocked by Trump's attacks on Israel than I am with the still unknown details of the deal with Iran.

I'm still trying to believe it's all a pre-planned ruse with Israel as before. As for Iran, they can do a lot of damage before the deal is signed on Friday -- if it is signed at all.

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Cyrus no more. The Trump administration's apparent naivety towards Iran is either imbecility or dissimulation

Melanie Phillips, Jun 16, 2026 

"The shock and distress in Israel are palpable. President Donald Trump’s apparent volte-face on Iran is being felt as an abandonment.

"Israelis are used to the indifference or hostility of American presidents. They managed to survive the malevolent manipulation of the Obama administration and the intimidation and threats of the Bidenites.

"But in Trump, here was a president who brought about something no-one had thought would happen — the United States and Israel fighting side by side to defeat one of the greatest evils in the world.

"On that terrible day of October 7 2023, when Israel was subjected to a barbaric invasion that exposed its weakness against a seven-front attempt by Iran to exterminate it with hundreds of thousands of missiles pointing straight at it, who would have thought that within a couple of years Iran and Hezbollah would be on their knees with their senior ranks taken out, their missile stocks radically depleted, Iran’s air defences obliterated and its nuclear weapons programme, which had been on the cusp of coming to murderous fruition, set back by years.

"It was Trump, to his enduring credit, who made that possible. Accordingly, he was hailed as a new Cyrus, the 6th century BCE Persian king who freed the Jews from captivity and helped rebuild the Temple in Jerusalem.

"Yet this week, the same Trump seemed to be pulling defeat from the jaws of victory. By signing an agreement with the very Iranian regime that he should have been continuing to destroy, he has instead thrown Tehran a lifeline; reduced America to a paper tiger; accordingly put a spring in the step of Russia, China and North Korea, as well as emboldening Islamists seeking to destroy the west — and having undermined Israel’s security, aggressively turned on Israel for presuming to defend itself.

"The US not only excluded Israel from discussions leading up to the Memorandum of Understanding (MOU) but also, while currently keeping its terms secret from the world, has refused even to show them to the Jewish state.

"That’s Israel, America’s close ally and indispensable “unsinkable aircraft carrier;” Israel, which Iran is making every effort to wipe off the face of the earth; Israel, whose soldiers have been dying not just to save their own country but in defence of an America that refuses to put its own troops in danger but is all too happy for Israelis to die in defence of itself and the free world.

"Contrary to much misreporting, the MOU is not a deal that ends the war. It’s rather a framework for negotiations during a 60-day ceasefire. In a blizzard of claims and counter-claims, we don’t know what its terms are. But what’s undeniable is that Trump has chosen this moment, when the Iranian regime was weakening by the day, to take his knee off its windpipe by lifting the US blockade of Iranian ships. Going into the 60-day negotiation, he has thus chosen to make Iran stronger and the US weaker.

"Worse, there are suspicions that he will allow money to start flowing into Tehran’s coffers. Vice-president JD Vance has repeatedly stated that Iran won’t benefit unless it complies with US demands. “The agreement says they are not getting a single dime of American money,” Vance insisted on Fox News. But the money in question isn’t America’s but Iran’s own frozen assets.

"Israeli TV’s Channel 14 reported a claim that the Islamic Revolutionary Guards Corps that runs Iran had no intention of honoring the agreement. IRGC Commander Ahmad Vahidi was quoted as saying:

"Let’s take all the money right now, and then we’ll do whatever we want."

"The CIA seems have borne out this bad faith. CIA Director John Ratcliffe reportedly told Trump and other senior officials that intelligence gained by the US raised serious doubts about Iran’s willingness to make the nuclear concessions that America is seeking in any final deal.

"While we don’t know the terms of the MOU, statements by Trump and Vance are themselves causing great concern.

"The US originally said Iran must not enrich uranium, period. Yet Trump has told The New York Times that Iran would be permitted to enrich uranium at a low level and never for military purposes. But how low? It’s possible to get quite easily from some relatively low levels to weapons-grade enrichment in a short space of time.

"Trump has said repeatedly that Iran will never get a nuclear weapon, and if it tried it would suffer “unbelievable consequences”.

"But he has also said:

"We are talking to them about a 15 to 20-year ban."

"Well, which is it? This sounds exactly like the 2015 Obama deal which, with the US declaring then too that Iran would “never get a nuclear weapon,” explicitly green-lit an Iranian bomb after just a few years’ delay.

"At the same time, Trump says Iran has agreed to “never have a nuclear weapon”. If so, why then does it need a 15 to 20-year ban? And since the Iranians have always lied through their teeth about this, how could anyone believe a word they ever say?

"The naivety being expressed by both Trump and Vance borders on imbecility. Or is it cynical dissimulation? Vance says the big difference from the Obama deal is that Iran will be required to verify its commitment not to build a nuclear weapon. But the Obama deal also requited verification. Tehran merely hid what it was doing in sites unknown to the nuclear inspectors or from which they were barred.

"At the G7 summit, Trump said the Iranian regime had changed because so many former leaders had been killed. The people in charge now were “very rational” people. He said:

"They were nice to deal with. They were strong people, smart people. I think actually they’re smarter than the first and second group, but they’re not radicalised and they’re, you know, looking to help their country."

"But the Iranians charming the apparently witless US team are obviously telling the Americans what they want to hear — such as, according to Trump, that they now realise their four decades of waging war on the free world had been a mistake. How can any sentient being believe such patent nonsense? Iran is still being run by the IRGC who are no less fanatical than the regime has ever been — maybe even more so.

"Meanwhile, on Monday night Hezbollah broke its own ceasefire for the umpteenth time by firing numerous rockets toward IDF soldiers in Lebanon. Defeating Hezbollah is absolutely critical for Israel, whose north is at risk of becoming depopulated under the never-ending bombardments from Hezbollah.

"But this proxy army is vital for Iran. So it’s demanding that the MOU ceasefire must include Lebanon. And although it does not, Trump is now appallingly taking Iran’s side by pressuring Israel to stop fighting there to keep his “deal” on track.

"His remarks on this at the G7 summit in France were deeply shocking. He said:

"Israel’s fighting Hezbollah for too long, and too many people are being killed. You don’t have to knock down an apartment house every time you’re looking for somebody because there’s a lot of people in those apartment houses and they’re not all Hezbollah, that I can tell you..

"I’m not happy with the way Israel has handled themselves with Lebanon and with Hezbollah. They should have been able to do the job faster. It just goes on forever. And when that happens, it throws a negative light on the big deal, and that’s the deal with Iran…

"I suggested to Israel to let Syria take care of Hezbollah, Because to be honest with you, I think they’d do a better job of doing it."

"And he said of Syria’s president Ahmed al-Sharaa:

"He’s very capable. And he’s been very good for me. He’s protected everything that I’ve asked for. If Israel can’t do the job without killing everyone else, he’ll do the job. Syria will do the job…

"Without the United States, there would be no Israel. Without me, there would be no Israel — because no other president was willing to do what I did. I had a great relationship with Bibi, but now Bibi has to be more responsible with respect to Lebanon.

"Thus Trump ignored the fact that, just like Hamas in Gaza, Hezbollah situates its machinery of war in and around civilian homes; and he would deliver Lebanon to al Sharaa, who is ISIS in a suit — all the while denigrating Israel’s formidable challenge in Lebanon, its skill in dealing with it, and the terrible sacrifice of its soldiers’ lives it is being forced to make there.

"So Israel now faces an excruciating choice — between abandoning its northern citizens to Hezbollah attacks, and risking a vindictive Trump cutting off the military support necessary to keep itself alive.

"Americans may not realise it, but Trump’s lethal fantasy that he has transformed the genocidal fanatics of Tehran into people whose highest goal now is to emulate the prosperous burghers of Switzerland, where Friday’s MOU signing ceremony is to take place, is putting America itself at grave risk.

"As for those Israelis who allowed themselves to put their trust in this most capricious of princes, they forgot the basic lesson of their history — that the Jews are always alone."

FBI Thwarted a Major Terrorist Attack

Thank goodness for this FBI.  And thanks to a family member of one of the plotters; he saw something and said something.

These evil plotters deserve to be publicly perp-walked to serious prison time. 

Where'd  they get the idea from -- the Democrats'  and other groups' constant anti-Trump, anti-Israel, anti-capitalism rhetoric, perhaps? "Toning it down", as VP Vance suggests, is not going to work, because it hasn't worked yet despite years of anti-Trump assassination attempts, bombings, fires, and riots. 

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Fox News 6-16-26

FBI disrupts alleged explosive-drone plot targeting White House UFC event, officials say.

Signal chats allegedly revealed 23 people discussing pre-operational activity 

"FIRST ON FOX: The FBI and its law enforcement partners disrupted an alleged plot targeting this weekend’s UFC Freedom 250 event in Washington, D.C., officials told Fox News Digital.

"Five people were in custody as of Monday, and investigators identified 23 people as part of a potential network of plotters. The alleged plan involved using explosive-laden drones to hit buildings near the event, force a mass evacuation and steer crowds toward a pre-staged sniper team, officials said.

"A "second wave" was then allegedly planned to storm the White House gate, according to officials.

"The FBI first learned of the threat on June 10 and worked with partners to secure probable cause for an arrest in Cincinnati, where one suspect was taken into custody. Court documents identified the suspect as 19-year-old Tycen Proper. 

"Two others, identified as Bryan Omar Roa and Michael Alan Thomas, were arrested in California for alleged involvement in the plot. Both men were charged with conspiracy to commit murder. They appeared in court on Monday in Riverside.

"Other suspects were arrested in Missouri and Nebraska. Multiple sources told Fox News that those in custody are American citizens, and a foreign nexus was not involved.

"According to a criminal complaint, Proper allegedly spent $3,000 of his "graduation money" to purchase "lots of" ammunition, guns, extra magazines and other items for the alleged attack

"Authorities estimated that several boxes of ammunition that Proper had allegedly acquired contained thousands of rounds. It is also alleged that Proper acquired an AR-style rifle, a bullpup rifle painted with the American flag and two plate carriers with AR-style magazines. His family voluntarily turned over the equipment to law enforcement.

"His father told officers that Proper had quit his job to meet up with people he had met online to conduct "missions" and "recons," according to the complaint.

"The U.S. Secret Service said it "worked closely" with the FBI during the investigation.

"In the days leading up to this weekend, our special agents, mission support personnel, and technical security teams worked around the clock to identify those responsible and hold them accountable," Secret Service Director Sean Curran said in a statement. "Equally important to our protective mission is ensuring accountability through the justice system. To that end, our formal comments regarding the specifics of this case will be made through court filings."

"Investigators later uncovered Signal chats in which multiple people allegedly discussed attacking the UFC event. An initial review of one suspect’s iPhone identified at least 23 Signal users discussing pre-operational activity, officials said.

"Some of those involved allegedly planned to travel to Fredericksburg, Virginia, on June 12 or 13 to prepare for the attack.

"One suspect allegedly told investigators the goal was to target "capitalist elites," "billionaires" or politicians who received donations from the American Israel Public Affairs Committee.

"The investigation stretched across at least 12 FBI field offices.

"FBI Director Kash Patel credited the FBI, the Department of Justice (DOJ) and law enforcement partners with acting quickly across multiple states to prevent the alleged attack.

"Thanks to the rapid action of this FBI, our partners, and the Department of Justice in a multi-state operation, multiple individuals are now in custody and allegedly planned attacks were stopped cold," Patel said in a statement to Fox News Digital.

"Patel said the operation showed the FBI’s ability to respond quickly when threats emerge.

"While the result represented the best of investigative work, it was also nothing out of the ordinary for this law enforcement team," Patel said. "We are built to detect, respond to, and bring to justice those who threaten the lives of American citizens — particularly during large gatherings like the historic UFC 250 fight. That’s exactly what we did here."

"I want to thank our great agents and partners, this work remains ongoing, and we will continue to update the public as permitted," Patel added.

"The alleged plot targeted UFC Freedom 250, a high-profile White House event held on the South Lawn as part of President Donald Trump's 80th birthday weekend.

"The event drew an estimated 4,300 attendees, including about 1,200 active-duty service members, as 14 fighters from around the world competed inside a wire-mesh cage Sunday night.

"Reacting to the news on "FOX & Friends" Tuesday, Vice President JD Vance called it "very, very dark stuff."

"This is what happens when people turn the rhetoric up so loud that disagreeing with somebody is a cause for violence," Vance said. "We got to tell everybody to tone it down."

"Everybody has a role to cut this stuff out," Vance continued. "But I think a lot of my Democratic colleagues in Washington have got to look themselves in the mirror and say, why is so much of this political violence coming from our side of the spectrum?"

 "The alleged plot comes amid a growing series of threats and security incidents involving Trump and senior administration officials, fueling heightened concerns about political violence."

Your Local Epidemiologist: The Dose, 6-16-26

Joy is contagious. Also: mosquitos, infant botulism, H5N1, peak tick season, and more.
The Dose 
Katelyn Jetelina, Jun 16, 2026

I’m not a big basketball fan, but boy, the sound of Manhattan at the final buzzer of the NBA Finals was electric in every video I came across: cheering, weeping, horns honking, singing, hugging, cigars being lit, an utter unselfconsciousness, pure and absolute jubilation. It gave me goosebumps. It’s a reminder that joy is contagious. Congratulations, New Yorkers, and thank you for the reminder of the value of community and shared joy. More of that, please.

Speaking of shared joy, the World Cup has officially kicked off, and we are here with what the health data show. We’re also at peak tick season, and mosquitoes and infant botulism have entered the chat. Other low-risk but high-consequence things are happening, including bird flu heating up among cows again.

And pediatricians are getting bombarded with vaccine questions. We answer the latest and update a resource for you.

Here’s what’s going on and, most importantly, what it means for you.


Disease “weather” report

We are at peak tick season

Across much of the U.S., we’re in the heart of tick season. After starting earlier than usual, it’s now tracking close to previous years. I’m hopeful we’ll see activity taper off over the coming weeks.

Source: CDC; Annotated by YLE

What this means for you: It’s still important to enjoy the outdoors, so prevention is the name of the game. Use an EPA-approved repellent, wear long pants when possible, and do a quick tick check afterward. The vast majority of ticks don’t carry diseases, but regardless, the sooner a tick is removed, the lower the risk of transmission.

Mosquito season is here

Mosquito season is ramping up across much of the country. We can expect mosquito-borne diseases to peak in August or September.

Why? Mosquitos are cold-blooded, so transmission is a bit like a chemistry experiment. If it’s too cold (below ~16°C or ~60°F), the mosquito life cycle slows down too much to spread disease. Closer to the “magic temperature” of ~25°C / ~77°F, mosquitoes are happier and diseases spread a little more easily from mosquito to human.

West Nile is the leading cause of mosquito-borne disease in the U.S. It is a fairly new disease—25 years ago, we didn’t have it around. But it is very rare. So far this year, we’ve seen only 13 cases of West Nile. (In June 2025, we had 62 total and August had the most cases at 958)

What this means for you: Your risk depends on geography and other factors, including older age. As mosquito populations grow, it’s worth dusting off the bug spray and clearing standing water around your home.

Low risk to you, but disease of high (and potentially) consequence

Several outbreaks are on my radar, but all remain very low risk to the general U.S. public:

  • Another infant botulism outbreak tied to baby formula. Nara Organics has recalled its organic formula, sold nationwide at Target, after three babies between 2 and 5 months became critically ill in CA, PA, and WA. Like the ByHeart recall last fall, it’s a niche product (under 1% of supply). What makes this one sting a little more: ByHeart had actually pointed parents to Nara as the safe alternative after their own recall. Regardless, it’s a reminder of how much we depend on the systems around us working.

  • Ebola cases in Africa have climbed to 808, including one of the largest single-day jumps over the weekend. The cumulative total has already surpassed what the two biggest prior outbreaks reached at the same point in their first 100 days. This is a sign this one is likely to grow very large. If you're traveling to Africa (or have patients traveling), check out the YLE decision tree here.

Cumulative Ebola cases in first 100 days of outbreak declaration. Markers are values from WHO/CDC/ECDC situation reports. Figure by Your Local Epidemiologist
  • Bird flu (H5N1). After months of relative quiet, the USDA reports a sharp jump in infected dairy herds: in the past 30 days, 45 tested positive in Idaho, 2 in Utah, and 1 in Texas. We’re not at 2024 levels, but this is more than we’ve seen in a while.

H5N1 dairy herds. Purple: updated figure with USDA numbers since CDC figure has only been updated since June 3. Source: CDC and USDA.

Healthy Cup

The World Cup has officially begun, and the good news is that there have been no significant health events so far. Overall health risks remain low, but we’re watching three signals:

  1. Heat. On opening day, Fan Fests in the Texas area saw nearly 100 fans fall ill from the heat, some requiring hospitalization. This is concerning because for every reported heat illness, many more sit just short of emergency, like dehydration and falls, cardiac problems, kidney stress, and mental status changes in elders. The “count” (22 out of ~30,000 attendees) underestimates the harm. Keep cool; drink water; know that alcohol and drugs mask heat injury symptoms, and common medications increase heat vulnerability. Go here to see your heat risk this week.

  2. Measles. A few outbreaks are happening in the background, but two “sparks” sit particularly close to World Cup events, and we need to ensure they don't turn into wildfires:

    1. Wastewater monitoring has detected a signal in Chester City, Delaware County (15 miles from Philadelphia Stadium).

    2. One case among an unvaccinated resident in Santa Clara County, California, with recent international travel and community exposure, including at the airport.

  3. What other things are people worried about? The YLE weekly survey of World Cup goers started last week. No major health rumors are surfacing yet (only 13% have heard any), but there’s concern about traffic and transportation accidents, as well as ICE.

Figure from Your Local Epidemiologist

Good news

We can always use it. Three today:

  • FDA clears a screwworm treatment for dogs and cats. The FDA authorized emergency use of generic nitenpyram tablets for infected pets, expected to kill most larvae within hours. New World screwworm numbers continue to climb, with 12 animal cases across 7 counties. This medication is not preventative but an important new tool if an infection occurs—and more will be happening given how quickly this thing spreads.

New World screwworm detections by county. Figure from a dashboard created by Genompic Epi.
  • A new sunscreen ingredient, the first in over two decades. The FDA has approved bemotrizinol, used for years in Europe, Asia, and Australia, where it’s prized for strong, stable protection against both UVA and UVB. The approval spotlights a U.S. quirk: because sunscreens are regulated as drugs here, new ingredients can take years or decades to reach consumers. Products could appear later this year, though wide availability will take time. Read more about sunscreen at the YLE deep dive here.

  • A lab-grown heart-muscle patch. Researchers implanted a stem cell-derived patch of heart muscle onto the failing hearts of 16 patients with advanced heart failure. The effect was real but modest, more of a signal of progress. Read more here.


Question grab bag

“This week I have encountered several patients saying “vaccines are only studied for 5 days.” Can you update your 12 questions about vaccines handout to address this succinctly? It would be very much appreciated. - A tired pediatrician.”

This is a common rumor. That figure comes from a line in the package insert describing the short window when vaccine trial participants fill out a daily diary card (see below for an example). But that card is only tracking the expected, short-lived reactions to a vaccine (sore arm, redness, fever, fussiness), which are caused by the immune response itself and reliably fade within a few days. Symptoms that persist longer usually point to a different cause, like an unrelated infection picked up around the same time, so that brief window is all the diary card needs to cover.

Chart from Appendix 3 here has an example showing what these look like.

But vaccine monitoring doesn’t stop there. The same trials track other health events for months to years, recorded as they happen rather than on a checklist. And for routine childhood vaccines, those original trials are now just the starting point: we have real-world safety data on hundreds of millions of children across decades, consistently showing that the benefits far outweigh the risks.

We’ve updated the FAQs for paid subscribers, with the latest is available below. Thank you for all your effort, and all clinical care teams on the front line. 

"Not Interested In Working For a Jew"

I haven't been able to get this brazenly antisemitic incident out of my mind, partly because something similar happened to my father when I was a kid.  After speaking with a potential customer over the phone, my father was informed by the boss that the customer had then complained to him that he didn't want to work with a Jew. So my father was told to change his name and use a non-Jewish-sounding last name from now on instead.

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Contrast Franco's unapologetic hatred to the Einhorns' regret at exposing him. They are model young Jewish businessmen, and I hope their startup thrives.

This hateful Cornell student should be blacklisted and not get any interviews or jobs with any decent employers, Jewish or not.  

Of course, the anti-Jewish campus activists and anti-Israel rioters would be thrilled to have such a Jew-hater working for them, and he is probably going to be extolled as some sort of hero. The antisemites deserve him. 

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New York Post 6-13-26 

Antisemitic Cornell student turns down interview because he's 'not interested in working for a Jew'

"A Cornell University student who applied for a summer internship with a Jewish-owned NYC startup rejected the opportunity with a hateful message: ‘Not interested in working for a Jew,” the shocked CEO posted on X.

"Austin Franco put his antisemitism on full display when he passed up an interview with VryfID because its co-founders Gabe and Aiden Einhorn are proudly Jewish. 

"Franco, 19, delivered the message to both brothers via job board site Handshake after applying for a summer role at the company, which pairs renters with landlords and verifies their identities to prevent fraud. 

A picture of Austin Franco.

Austin Franco, 19, declined a job interview because he didn’t “want to work for a Jew.” Linkedin / Austin Franco

The two brothers posed together wearing suits.

Aiden, left, and Gabe, right, started the company together in the summer of 2025. Courtesy of Gabe Einhorn

"The Einhorns reviewed Franco’s application and he was being considered for an internship with VryfID’s growth team, which is tasked with attracting renters to the company.

“Sad world,” Gabe, 24, wrote on X Monday along with a screenshot of Franco’s jaw-dropping eight-word response to trying to schedule a Zoom call: “Not interested in working for a Jew. Thanks.” 

"Gabe Einhorn told The Post he felt obligated to share the message to raise awareness of growing antisemitism. He blacked out Franco’s name out of graciousness, but commenters quickly revealed his identity. 

“I felt bad exposing him because I thought he could have made a mistake and he really doesn’t believe this wholeheartedly,” Gabe said. 

"But the Ivy Leaguer soon made it clear that he meant every word of what he wrote. 

The student who hails from Virginia doubled down in an X post shared the next day.

A head shot of Gabe Einhorn.

VryfID CEO Gabe Einhorn, 24, co-founded the company with his brother last summer. Linkedin / Gabe Einhorn

My experiences with Jews have not been pleasant, both in person and online. This is not to say I haven’t had positive experiences, but on the aggregate that is not the case,” Franco wrote.

"Cornell — where Franco studies industrial and labor relations, according to his since-deleted LinkedIn profile — is investigating the incident. He sent the disgraceful message on Monday, about a month after Cornell’s semester ended.

“Cornell condemns antisemitism and all forms of hatred and discrimination in the strongest possible terms,” a university spokeswoman told The Post.

"Gabe and his younger brother Aiden, a 22-year-old NYU business student, launched VryfID in the summer of 2025.  

A photo of his LinkedIn profile.

Franco attends Cornell and is studying labor relations, according to his since-deleted LinkedIn.

“Instead of renters struggling to search for apartments and getting rejected, we have them sign up, pay $20 to get verified. Then we actually bring them apartments that they actually qualify for,” Gabe explained to The Post. 

“For landlords, it helps them fill up their units and brings them the right tenants.”

"Aside from content centered around the NYC rental market, Gabe, who wears a kippah, often speaks about his faith across his growing social media platforms. 

“I’ve seen some terrible things across the board — antisemitic things and just terrible things in general,” Gabe said, adding that he had about five death threats just on Facebook the last time he checked. 

A photo of the post.

Franco doubled down on his hatred in a response posted on X.

“People just like to spread hate across social media because they’re anonymous and they have no repercussions.”

"The hateful message has left the brothers stunned. 

“Me and my brother kind of looked at each other like, ‘What?’ We never really experienced [antisemitism] this directly,” Gabe said.

“The whole thing was just very shocking and uncalled for.”

"Franco did not return requests for comment. His father, Alexander, a patent attorney, declined to comment."

Monday, June 15, 2026

Dr Ruth Report 6-14-26

Here's the latest comprehensive medical report from Dr. Ruth Ann Crystal. There's so much to learn from her newsletters!

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Dr. Ruth Report, 6/14/26
Ruth Ann Crystal MD, Jun 15, 2026 

COVID levels in wastewater are at their lowest since 2021, except for a few hot spots in Ohio, Idaho, Florida and Maine. We will have to wait and see if the World Cup games will have any effect on COVID levels, or on measles cases for that matter.

Using Biobot and CDC data through June 6, Mike Hoerger estimated that about every 1 in 269 people was currently infected with COVID, with 182,000 new COVID cases each day in the United States.

This week, research shows autoantibodies in kids after COVID infection, decreased glucose metabolism in the brains of people with Long COVID, an ultrasound patch that can continuously monitor the fetus in pregnancy, inhaled insulin for kids with diabetes, and much more.

Pediatrics

Antibody repertoire associated with clinically diverse presentations of pediatric SARS-CoV-2 infection | Nature

Long-Term Outcomes of Multisystem Inflammatory Syndrome in Children (MIS-C) up to 4.5 Years After COVID-19 | Pediatrics (AAP)

  • Montefiore Health System researchers tracked 14,363 children and adolescents and found that MIS-C was associated with elevated risks of cardiac, pulmonary, gastrointestinal, neurological, renal, and blood pressure disorders persisting as long as 4.5 years after COVID infection. These findings underscore that the health burden of MIS-C extends well beyond the acute phase of illness. “Structured long-term follow-up, including routine blood pressure monitoring, neurological and mental-health screening, and cardiovascular and renal surveillance, with coordinated multidisciplinary care is warranted.”

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Vaccines

Menstrual cycle phase and its association with COVID-19 vaccine outcomes among period tracking app users | npj Women’s Health

  • London scientists, in collaboration with the Clue app, analyzed data from 1,474 women and found that receiving a COVID vaccine during the follicular (estrogen producing) phase of the menstrual cycle was associated with 35% greater odds of side effects as compared to the luteal (progesterone producing) phase, with longer lasting protection. “Median time to COVID infection was 35 days longer following follicular-phase vaccination (200 vs 165 days, p = 0.05), though infection numbers were limited,” and more studies are needed.

Sustained antigen-specific CD8+ T cell immunity post–mRNA booster requires notch pathway activation | Journal of Immunology

  • Japanese researchers followed 141 people after a third Pfizer COVID-19 booster and tracked spike-specific CD8+ killer T cells for six months. People who maintained strong T cell responses showed higher activity of the Notch signaling pathway, while those whose responses waned did not. Blocking Notch signaling in the lab prevented CD8+ T cells from expanding after re-exposure to spike protein. These findings suggest that Notch signaling helps sustain long-term killer T cell immunity after mRNA vaccination and may be a target for improving future vaccines.

Long COVID

Persistent Cerebral 18-FDG PET Changes in Patients With Long COVID Presenting With Fatigue and Post Exertional Malaise | J of Primary Care & Community Health

  • Scientists from Mayo Clinic examined 40 Long COVID patients experiencing fatigue and post-exertional malaise (PEM) and found measurably decreased cerebral glucose metabolism via 18F FDG PET imaging, concentrated in sensorimotor and visual brain regions. This pattern of reduced brain energy use persisted for at least two years after the initial COVID infection in patients with fatigue and PEM.

Figure 2. Representative 18F-FDG PET scan for a patient with Long COVID showing cerebral hypometabolism.

  • The bottom panel shows “near global hypometabolism particularly pronounced in the occipital lobes, correlating with the participant’s symptoms of cognitive dysfunction and fatigue with post exertional malaise.”

From: https://journals.sagepub.com/doi/10.1177/21501319261458748

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Single-cell profiling of innate and adaptive immune dysregulation in Long COVID | BioRxiV

  • Emory University researchers analyzed single-cell profiling on 156,478 peripheral blood mononuclear cells (PBMCs) from 20 Long COVID (LC) patients and 18 recovered controls (RC) and found that Long COVID patients show persistent immune cell activation consistent with ongoing viral antigen exposure. B cells remained in an activated state, T cells displayed markers of exhaustion, and NK cells lost normal function, collectively pointing to a system that cannot stand down from fighting an infection that may still be present in some form.

Beyond brain fog: viral proteins as convergent drivers of neuroinflammation and proteinopathy | Current Opinion in Virology

  • A new review from the University of Veterinary Medicine Hannover proposes that viral proteins persist after viral infections. These viral protein fragments can act as neurotoxins and can activate TLR4 and TLR2 toll-like receptors on glial cells which triggers neuroinflammation even when live virus is absent from the nervous system. The inflammatory cytokines made by glia cells and astrocytes can also activate tau and alpha-synuclein proteins to accumulate in the brain. Tau protein is associated with Alzheimer’s disease and alpha-synuclein with Parkinson’s disease and Lewy body dementia. This offers a concrete molecular pathway connecting post-infectious illness, including Long COVID, to lasting cognitive (brain fog) and neurological symptoms.

From: https://www.sciencedirect.com/science/article/pii/S1879625726000519#fig0005

Intracellular microbial shifts during COVID-19 infection and longitudinal recovery revealed by single-cell RNA sequencing | iScience

  • Scientists in India performed single-cell RNA sequencing of 191,417 peripheral blood mononuclear cells (PBMCs) from 57 individuals (9 healthy, 24 Omicron-infected, 16 recently recovered, 8 Long-recovered) and discovered that SARS-CoV-2 infection altered the microbial communities residing inside immune cells, with opportunistic bacteria accumulating specifically within T cells and platelets. Over the course of extended recovery, the intracellular microbial composition in these individuals gradually shifted back toward the patterns observed in healthy people.

Salivary microRNA Profiling of Long COVID Subjects Reveals Host-Encoded Regulators of Inflammation and Viral Persistence | BioRxiV

  • Researchers from the University of Illinois Chicago studied 30 participants and found that Long COVID patients with periodontitis had widespread depletion of salivary microRNAs that ordinarily suppress NFκB driven inflammation and are capable of binding SARS-CoV-2 RNA. When those microRNAs were reintroduced in cell experiments, both inflammatory signaling and viral gene activity measurably declined.

COVID‐19 as a Potential Trigger for Tuberculosis: Insights From a Large‐Scale Japanese Insurance Database Analysis | J of Family and General Medicine

  • A retrospective cohort study from Japan of over 6 million people shows that COVID infection is associated with a 4x risk of needing Tuberculosis treatment. In those who had prior tuberculosis, risk was 14.7x higher after COVID infection, showing that COVID infection may increase the risk of Tuberculosis reactivation.

A more than fourfold increased risk of active TB treatment initiation following COVID-19.

From: https://onlinelibrary.wiley.com/doi/10.1002/jgf2.70139

Immunothrombosis in hospitalized COVID-19 patients identified by multiomics profiling and linked to postacute complications | iScience

  • A group from Latvia followed 81 hospitalized COVID patients and found that blood drawn three months after severe infection continued to show measurable abnormalities in platelets, the complement system, and vascular function in 46 people with Long COVID. These persistent immunothrombosis signatures suggest that clotting related disruptions in severe acute COVID infection can leave a lasting biological imprint in Long COVID.

Immunoadsorption Versus Sham Treatment for Post-COVID Syndrome: A Randomised Sham-Controlled Crossover Trial | Lancet Regional Europe

  • Researchers from Mainz, Germany tested immunoadsorption in 40 Long COVID patients to determine whether removing GPCR autoantibodies from the bloodstream would relieve Long COVID symptoms, but outcomes did not improve compared to the sham procedure. Immunoadsorption also produced adverse events at a higher rate than the control condition.

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Measles

CDC Measles updates (on Wed.):

  • As of June 11, 2026, 2,073 confirmed measles cases were reported in the United States in 2026.

John Hopkins US Measles Tracker

  • There have been 86 new measles cases, mostly in Utah and Virginia.

Other news

Fetal monitoring for high-risk pregnancies using a wearable ultrasound patch | Nature Biotechnology

  • This may be a game changer for obstetrics. UC San Diego researchers developed a wearable ultrasound patch (UPatch) for continuous fetal ultrasound monitoring. Tested on 62 pregnancies, the UPatch matched handheld clinical ultrasound readings and tracked fetal blood flow in real time autonomously without a sonographer. Continuous UPatch ultrasound monitoring in 52 pregnant women successfully stratified high risk obstetrical conditions including preeclampsia, gestational diabetes, and fetal growth abnormalities.

From: https://www.nature.com/articles/s41587-026-03140-1

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FDA Approves Inhaled Insulin for Children, Adolescents With Diabetes | AJMC

  • The FDA approved Afrezza (inhaled insulin human) for children and adolescents ages 6 and older with type 1 or type 2 diabetes, making it the first needle-free mealtime insulin option for pediatric patients. The phase 3 INHALE-1 trial showed no significant pulmonary safety signals, and treatment satisfaction was higher in the inhaled insulin group for both patients and parents.

Microbiota-driven gut-brain signaling underlies antidepressant effects of a GLP-1 analog | Cell

  • Chinese scientists showed that liraglutide reduced depressive behavior in mice through a pathway that bypasses its known GLP-1 receptor, instead operating through changes in gut bacteria. The drug selectively increased Lactobacillus delbrueckii populations in the gut, which in turn increased endocannabinoid 2-arachidonoylglycerol (2-AG), which then suppressed stress-related overactivation in brain circuits related to depression.

Gut microbiota-derived short-chain fatty acids (SCFAs): immunomodulatory effects and therapeutic potential in infections | Clinical Microbiology Reviews

  • A new review examines how short-chain fatty acids (SFCAs), especially butyrate, propionate, and acetate, affect immune responses to bacterial, viral, and fungal infections. Gut bacteria produce SFCAs when they break down dietary fiber. SCFAs and SCFA-producing bacteria may support treatment of infections by strengthening the gut barrier, calming excess inflammation, and boosting pathogen clearance, but their effects vary depending on the microorganism and the SCFA concentration.

Fig 3 The regulatory effects of SCFAs on the intestinal barrier, host immunity, and distant organs.

From Fig 5: Interactions between SCFAs and viruses.

Made with Canva, based on https://journals.asm.org/doi/10.1128/cmr.00368-25

Interleukin-10 Autoantibodies and HLA-DRB1*01:03 in Inflammatory Bowel Disease | NEJM

  • Interleukin-10 (IL-10) is an important anti-inflammatory cytokine. Researchers in England discovered anti-IL-10 autoantibodies in 3.5% of 4,909 Inflammatory Bowel Disease (IBD) patients studied. IL-10 autoantibodies were highly enriched in people with HLA-DRB1*01:03, with odds ratios of 24.7x - 50.0x found across two large cohorts. High anti-IL-10 titers were associated with exaggerated proinflammatory cytokine release. The findings reframe IBD as a group of mechanistically distinct diseases and open a path toward targeted anti-autoantibody therapy in a subset of patients.

Explainer article can be found here:

Autoantibodies against Cytokines — From Infection to Inflammation | NEJM

I’m a Tech Expert. Here’s How I Prep My Devices for an International Trip. | NY Times (Article can also can be found at https://archive.is/Jr0y5)

  • Heading overseas this summer? A tech journalist’s pre-trip checklist: check your carrier’s international plan, grab an eSIM for cheap local data, download offline maps and translation tools, back up your itinerary and passport, and pack a universal travel adapter. He also recommends that before flying home, disable biometric unlock and consider hiding your social apps to protect your privacy at customs.

A former teacher reunited with students decades after inviting them to watch the 2024 solar eclipse together | Today

  • Retired Rochester science teacher Patrick Moriarty reunited with over 100 former students for a solar eclipse watch party he had planned 46 years earlier. In 1978, he told his 9th graders to mark April 8, 2024 on their calendars. He also extended the invitation to students in subsequent years. Decades later, his former students came from across the country, some with gray hair like him, to watch the solar eclipse with their favorite teacher.

Mr. Moriarty and some of his former students
Photo: Caitlin Moriarty Hynick

Have a great week,

Ruth Ann Crystal MD 

Sunday, June 14, 2026

UFC Match: Trump vs. Netanyahu

I've been trying to convince myself that this latest round of Trump castigating Bibi was just another ruse, but the more I watch the news, the less convinced I've been.

To sum it up, here's The Times of Israel

"Trump reportedly updates Netanyahu over phone that Iran deal may be signed tonight

"Reported progress toward deal comes after Iran was said to be incentivized not to attack Israel in response to Beirut strikes * Trump says Israeli attack shouldn’t have happened, none of Lebanon should be hit in future; says Netanyahu ‘has no f**king judgment’"

As if that wasn't bad enough, I then saw on TV that -- surprise! -- Tehran wants more time regarding the deal. So I shut off the news.

Iran has already had weeks to think about a deal. And we should not have stopped bombing them last week.

But when you attack our great ally Netanyahu for retaliating for Hezbolleh attacks on his country while begging a terrorist state like Iran to sign a deal today -- well, either that's the best piece of Oscar-winning acting I've ever seen, or else it sends a very wrong message to Iran. And now Iran will keep stalling because of our weakness.

I realize that Trump probably wants to be able to announce the nonexistent signed deal at the fights tonight to celebrate his birthday. But this is one thing that even he can't control. 

What he can control is the ability to issue a sincere apology to Netanyahu, ASAP.

Adopt-An-Antisemite".

Do anti-Israel/anti-Jewish extremists spend all their time thinking of ways to harass the Jewish people? Here's the latest example as reported at Elder of Ziyon.

Imagine if Jews did that with a "Jews for Israel" road sign in a Muslim neighborhood in Dearborn. We'd immediately be told to take it down because of "Islamaphobia".

---------------------------------------


"Melissa Brodsky notes on Substack that a road was recently "adopted" in West Bloomfield, MI by a group called "Voices for Palestinians" to be responsible for cleaning it up.

"A sign was placed on the road at taxpayer expense to mark the portion adopted.

"When people or organizations adopt a road in Oakland County, they get to choose from all available roads. So churches will typically adopt a road near their facilities, or people will adopt one in memory of a loved one who might have died in a traffic accident on that road. 

"Out of all the roads available in Oakland County, "Voices for Palestinians" chose Orchard Lake Road between West Maple Road and Walnut Lake Road - the epicenter of the Jewish community of West Bloomfield. There are at least 8 synagogues and at least three Jewish schools plus Jewish community centers and other Jewish organizations near that mile of road.

"Including Temple Israel, which was attacked last March by an Islamist terrorist. For Palestine. 


"There are no mosques that I can find in that immediate area.

"Who is "Voices for Palestinians?" I can find no mention of this group anywhere. There are plenty of pro-Palestinian groups in the Detroit metro area but this one seems to have no website, no social media presence. No one ever heard of them before this sign was put up.

"This is the only major road that hadn't already been adopted in the Jewish neighborhood.  The sign is northbound right at the entrance of the Jewish community. 

"It is hard to escape the idea that this organization was created just to get the county to put up the sign, with the primary purpose to intimidate the Jewish community of West Bloomfield.  It costs nothing, except volunteering twice a year. (And if they don't show up, the sign is still there for a year, so it does its job.)

"This is legal Jew-baiting."

Saturday, June 13, 2026

A Tracking Tool For World Cup Diseases

Hopefully this tool will help reassure the thousands of soccer fans who will be attending the matches here. For me, just seeing footage of 70,000 unmasked attendees in a stadium is scary enough.

From Corrie Pikul at Brown University 6-10-26:

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Using data from FIFA, Brown epidemiologists developed a tracking tool aimed at assisting public health experts in the event of an infectious disease outbreak.

PROVIDENCE, R.I. [Brown University] — With the FIFA World Cup 2026 competition kicking off in cities across North America, a Brown University research team is making it easy to track infectious diseases that could be spread by teams, players and fans.

The tool, developed by epidemiologist William Goedel at Brown’s School of Public Health, shows all World Cup sites and where people will be congregating. Users can sort by upcoming soccer matches to view information on team training sites, hotels and major fan gatherings.

“Any time you get a lot of people coming together for a large celebratory event, such as a sports tournament, you have to worry about public health challenges like infectious disease outbreaks,” Goedel said.

This World Cup is exceptionally complicated: Instead of one host country, as in the past, there are 48 soccer teams playing in 16 locations across the United States, Canada and Mexico — involving an unprecedented level of coordination and movement, according to Goedel. State health departments typically track disease outbreaks using tools like hospital records and wastewater surveillance. The new tool is meant to augment those systems.

“The explorer is intended to help people understand how teams and fans might be moving over the next couple of weeks,” Goedel said. “This kind of information is invaluable for public health experts so that if a disease outbreak happens, they can understand where it may have started and where it will spread next.”

Goedel built the tool using information from the International Federation of Association Football (FIFA), which organizes World Cup events. It is populated with the first rounds of play and has matchups for the later rounds, and it will be updated as the tournament progresses.

Goedel explained how the tool works: If a public health alert is issued for something that happened in Miami (like a measles outbreak at a fan fest), then public health experts will be able to see which teams recently played in Miami and where they’re headed next, as well as teams that will be staying or training in close proximity. While the intended audience includes public health experts and health departments who need to map the movements of teams, he said it’s equally helpful for fans who following their favorite teams.

Goedel noted that experts are less worried about headline-grabbing rare diseases like Ebola or hantavirus and more concerned with common, easily transmissible illnesses.

“Considering the high density of people from all over the world, we are more focused on COVID-19, measles and norovirus,” Goedel said. “The U.S. has had quite a struggle with measles over the last couple of months. Measles cases have been reported this year in every state that will host a team or match for the World Cup.”

Public health experts are also staying vigilant about deliberate biological threats: “We're in a tense geopolitical climate where that is a real concern, but that's also part of what public health preparedness is about: being able to anticipate threats during these large gatherings,” he said.

Kicking around ideas for a tournament tracker

Goedel is a faculty affiliate at Brown’s Pandemic Center and leads the center’s efforts to increase capacity for data-driven decision-making among staff at local health departments and their community partners. He has been helping the Rhode Island Department of Health (RIDOH) with emergency preparedness and response since joining the Brown faculty during the height of the COVID-19 pandemic in 2020.

As the World Cup approached, Goedel and Pandemic Center Director Jennifer Nuzzo reached out to RIDOH colleagues to see where they could help. The researchers had noticed that this major global event was not only complicated but confusing: FIFA was rebranding stadiums by location, so nearby Gillette Stadium is being referred to as the Boston Stadium, even though it’s closer to Providence — and Rhode Island’s healthcare systems.

One of the other challenges, from a public health standpoint, was tracking game locations and team movement.

“I'm a spatial scientist: My area of expertise is making maps to help people make decisions,” Goedel said. “I thought, let me put something together really quickly that will allow for the identification and tracking of stadiums, teams and dates. This explorer tool came out of an organic need to have a Google Maps-style interface to be able to track what's going on.”

The interactive maps were created using a web-based mapping software called ArcGIS Online, which Goedel teaches to students in a Brown public health course focused on geographic information systems.

“Most of the information underlying our tool is available from FIFA, but it’s not in usable form,” Goedel said. “We simply scraped the data from FIFA's website — catalogs of where teams are staying, game schedules, official fan zones — and made it so people could make the connections and look up information.”

A doctoral student is helping Goedel update the maps as more data becomes available.

These types of maps are not unusual, Goedel said: He created many of them during the COVID-19 pandemic. Typically, in the lead-up to a large international sporting event like the World Cup or the Olympics, local health departments will coordinate with federal partners to prepare and plan for at least a year.

“The government shutdown earlier this year meant that there were delays in getting funds out the door to support public health planning efforts,” he said. “Over the last several years, the mass departures we've seen from the Centers for Disease Control, and the gutting of CDC budgets, have meant that there are fewer people centrally at the national level who are able to help coordinate these kinds of responses.”

Although the games won’t start until June 11, the explorer tool has already been used in and beyond Rhode Island, Goedel said. The School of Public Health hosts the STAT Network, which convenes state health officers around public health issues, and several host states have integrated the tracker into their public health planning toolkit. It has been integrated into the Pandemic Center’s weekly infectious disease tracking report and is embedded in the World Health Organization’s Mass Gathering Network platform.

For public health experts, Goedel said that the most likely scenario for the World Cup is that nothing serious happens.

“Health departments tend to do a really great job at preparing for these kinds of events, such that they identify people as soon as they get sick and get them out of interacting with the public as quickly as possible,” Goedel said. “The World Cup in 2014 and the Olympics in 2016 were both held in Brazil when there were real concerns about Zika virus. The World Cup in 2022 had concerns about Middle Eastern Respiratory Syndrome (MERS). The Olympics in 2020 in Tokyo and 2022 in Beijing all had significant concerns about COVID. There have been outbreaks of measles, botulism, flu and norovirus, but in almost all of these previous mass sporting events, we did not see really large outbreaks.”

Goedel is cautiously optimistic about this year’s World Cup.

“I’d like to hope that the biggest public health challenges will involve rough hangovers after late-night celebrations of the winning teams,” he said.