Cumulative Confirmed COVID-19 Cases

Thursday, May 15, 2025

Sound Familiar? "We have learned nothing from COVID-19"

From the National Post, Canada, 5/14/25:

Chris Selley: We have learned nothing from COVID-19; Vaccination rates are actually dropping, and influenza deaths are soaring 

"As readers will no doubt have heard, measles is back — especially in Ontario, which has reported 83 per cent of cases in Canada so far this year; and especially in southwestern Ontario, among largely unvaccinated Anabaptist communities, which Ontario’s chief medical officer of health, Dr. Kieran Moore, says account for 70 per cent of cases.

"As of April 26, Health Canada reported 1,506 measles cases nationwide, up from just 69 at this time last year; of those 1,506, only 74 infected individuals are known to have had one or the recommended two doses of the MMR (measles, mumps and rubella) vaccine, while 83 per cent are known to have been completely unvaccinated.

"According to the U.S. Centers for Disease Control (CDC) , between one and three children per 1,000 who contract measles will die from it, or from complications of it, notably pneumonia and encephalitis. And about 20 per cent of unvaccinated sufferers, of all ages, will wind up in hospital.

"It’s nothing if not frustrating. One might think the great success of COVID-19 vaccines would encourage people to appreciate better-established vaccines like MMR (mumps, measles and rubella), which has been around longer than I have been alive. Instead, by many accounts, the decline in routine vaccine uptake already occurring before the pandemic has continued to decline.

"As worrying as measles is, North America’s nasty flu season this year seems to have received much less attention. And it’s vastly more deadly.

"Around this time last spring, the U.S. Centers for Disease Control (CDC) estimated there had been in the United States “at least 34 million illnesses, 380,000 hospitalizations, and 24,000 deaths from flu so far.” Last year was considered a bad year for the flu.

"This year so far: “47 million illnesses, 610,000 hospitalizations, and 27,000 deaths.”

"At this time last year, the CDC reported that 164 children had died in the U.S. from the flu. This year, the number is 226.

"For comparison’s sake, the most American children who died from COVID-19 in any 18-week period was 944. So obviously COVID was much more dangerous, but the flu is no joke. COVID was all anyone talked about for two years; meanwhile, hardly anyone talks about the flu as a serious threat to life or long-term health, least of all among children.

"Canada is so allergic to data that it should carry an EpiPen; so we don’t have anything like as clear a picture of what’s going on here with the flu as they do in the U.S. — especially with respect to outcomes among children. But the picture we have suggests Canada has suffered more or less the same problem as the States, as you would expect.

"But Statistics Canada’s mortality figures tell an interesting tale: In 2020, 2021 and 2023 combined, 62 Canadian children are recorded as having perished from COVID-19 — and 103 from “influenza and pneumonia,” which is the International Classification of Diseases (ICD) code under which Canada reports flu deaths.

"During the pandemic, to compare COVID-19 to the flu was to invite the whole world to jump down your throat. And in many senses, indeed, they aren’t worth comparing: 47,000 Americans died of “influenza and pneumonia” in 2022, a year in which COVID-19 killed 271,000.

"But recall how often you heard politicians saying during the pandemic that we needed to lock everything down, close schools and playgrounds and skate parks for the sake of the children? Very early on in the pandemic, we knew that was a filthy lie: We were keeping kids home not primarily or even significantly for their own safety, but for their parents’ and especially their grandparents’ safety.

"Politicians knew that the saving grace of COVID-19 was that it didn’t target otherwise-healthy children for death. But they also knew that “think of the children” was the easiest way to sell restrictions on everyday life, and so that’s what they used.

"Now we have a flu season that may well be killing more Canadian children than COVID-19, and there’s absolute silence. No one called for schools to be closed, for Canadian Tire stores to be divided into essential and non-essential goods aisles, for bars and restaurants to be shuttered, for returning travellers to be locked up in hotels for society’s amusement.

"These are the sorts of contradictions, conundrums and failures that all the pandemic inquiries we’re not getting should be looking into. Because we clearly haven’t learned anything at all from the pandemic nightmare except that we’re better than Americans … and our superiority complex was more than big enough to begin with.

"How little have we learned? Moore, Ontario’s chief medical officer of health, took some flak last month for daring to mention that the measles outbreak was hyper-concentrated in certain unvaccinated religious communities.

"Dr. Ninh Tran, of Ontario’s Southwestern Public Health District, warned that associating measles cases to certain communities might provide “a false sense of security for the general public.” As if Ontarians actually believe being Mennonite attracts the influenza virus.

“(B)eing part of any particular group or religion doesn’t put you at risk,” Tran told The Canadian Press; rather, your vaccination status does.

"Remember being told we shouldn’t wear masks because we’re too stupid not to let it provide us with “a false sense of security”? Remember being told we mustn’t associate diseases with certain populations, lest we succumb to prejudice and discrimination? Yeah, we’re back there. Zero lessons learned. Vaccination rates dropping. I just hope I’m already dead by the time the next pandemic comes along."

Tuesday, May 13, 2025

The "Migrants" That Democrats Don't Love

Boy, what  hypocrites the Democrats are -- or should they be called Democrites?  They try to break into the ICE detention center because they are so concerned about the criminal illegal aliens inside. They travel to El Salvador to meet with a "Maryland father".  They give away freebies like free phones, free housing, and free health care to millions of illegal aliens invited here by Biden, Harris, & Mayorkas.

But 50 white Afrikaners from South Africa? The ones who ruled during apartheid but who now are being subjected to black violence? Well, let's say I doubt the Welcome Wagon will be handing out freebies to them any time soon.  As The Babylon Bee puts it, Democrats Confused By Legal Immigrants Who Seem To Love America

This column says it very well. 

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Democrats: Millions of illegal aliens are good, handful of South African refugees are bad 

5/13/25 by Eric Utter, American Thinker

"Several dozen white South African refugees were recently welcomed to Washington, D.C., most proudly waving American flags.

"Deputy Secretary of State Christopher Landau and Department of Homeland Security Deputy Secretary Troy Edgar welcomed the refugees, who are fleeing racial discrimination, persecution, violence, and murder in their home country.

"Or, as President Trump termed it, “genocide.”

"Before signing an Executive Order meant to reduce drug prices, Trump told reporters at the White House:

“It is a genocide that is taking place that you people don’t want to write about. It’s a terrible thing that’s taking place and farmers are being killed. They happen to be white, but whether they are white or black makes no difference to me.”

"That would be because Trump is not racist.

"With comical hypocrisy, a CNN panel predictably declared that being “victims of crime” does not “entitle” white South Africans to asylum in the United States. However, Democrats and their media sycophants fervently believe that perpetrators of crimes do deserve asylum in the U.S.  Interesting position. Not to mention insane and remarkably evil.

"The Episcopal Church promptly and proudly trumpeted its racism, stating that, due to its “steadfast commitment to racial justice” it simply cannot lift a finger to help resettle endangered white Afrikaners from South Africa.

"Today’s Democrat-Media Complex believes — almost to a man — that human-trafficking, wife-beating members of terrorist groups or other criminal organizations who have entered the U.S. illegally have every right to stay in the United States permanently.

"They further believe that the 12 million to 15 million or so migrants who invaded the United States during the Biden presidency, unvetted and unchecked for COVID or any other disease, many during a worldwide pandemic and lockdown, should be treated as good — or preferably, better than — American citizens.

"But, by God, a handful of South Africans fearing for their lives and livelihood, persecuted by their government, and brought here by the current popularly elected presidential administration pose a clear and present danger to democracy, they say.

"The same folks who tolerated/encouraged the aforementioned invasion, and the “Summer of Love” looting and violence of 2020, in which numerous people were killed and $2 billion in damages were done to American cities, and who subsequently successfully clamored for the imprisonment of hundreds of people who, mostly peacefully, strolled through the Capitol Building on Jan. 6 to protest an election that they believed was stolen from them, are now apoplectic over fewer than 60 refugees from South Africa.

"They say hell hath no fury like a woman scorned. Well, I don’t know about that. But I am pretty P.O'd right now, myself.

"I say a spot in hell should be promptly prepared for hypocritical asshats like these."

Monitoring COVID In Singapore

Well, I'm glad to see that some countries are still monitoring their COVID cases and recommending masks:

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Planning a trip to Singapore? Mask up as Covid-19 cases are going up
press trust of india • May 13, 2025, 22:28:13 IST

"Health authorities in Singapore said on Tuesday they are monitoring the recent rise in COVID-19 infections, and there was no indication that variants of the virus circulating locally are more transmissible compared to the previous ones.

"COVID-19 cases are estimated to have increased to 14,200 in the week of April 27 to May 3, 2025, compared to 11,100 cases in the previous week, the Ministry of Health (MOH) and Communicable Diseases Agency (CDA) said in a statement.

"During the same period, average daily COVID-19 hospitalisations rose from 102 to 133, but the average daily cases in the Intensive Care Unit fell from three to two cases, the health authorities said, adding that hospitals are currently able to manage the increase in cases."

Monday, May 12, 2025

Your Local Epidemiologist: The Dose 5/12/25

Here's Dr Katelyn Jetelina with today's Dose. And this reminds me to comment about Casey Means, the nominee for US Surgeon General.  How have we gone from the respected Dr Everett Koop to an "influencer" as Surgeon General? Not very reassuring at all!

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Common colds surging, measles slowing, tomato recall, good news in New York, and things flying under the radar.

by Katelyn Jetelina, Hannah Totte, MPH,  and Edward Nirenberg 

"Happy Mother’s Day to all you moms, bonus moms, and cool aunts—I hope your often invisible, messy, and tiring yet rewarding work was celebrated!

"In somewhat related news, colds and allergies are up. Tomatoes were recalled, a listeria outbreak is causing hospitalizations, and the president’s pick for Surgeon General is generally unqualified. There is also some good public health news in New York, and some things I’m noticing under the radar.

"Here’s your dose of health information to feel equipped for the week.


Common colds and allergies are peaking

"Feeling sick? You’re not alone. Lab-confirmed cases of rhinoviruses and enteroviruses—better known as the common cold—are high across the U.S. This is normal for this time of year, with a typical peak in mid-May before easing up for the summer.

Source: CDC; Annotated by Your Local Epidemiologist

"Tree pollen is also surging, triggering a lot of allergy symptoms. Grasses will soon take over. This spring is another record-breaker for seasonal allergies, with more (and larger) particles in the air due to rising carbon dioxide levels and a warming climate.

Source: CBS News annotated by Your Local Epidemiologist

"What does this mean for you? Unfortunately, there’s no cure for the common cold, but here are a few YLE-backed immune system tips. As for allergies, here are at-home tips that can help.

"Note: Allergies can weaken your immune system and make you more vulnerable to viruses like the cold. On the flip side, colds can make you more reactive to allergens. It’s a vicious cycle.


Measles update

"The U.S. has surpassed 1,000 confirmed measles cases—1,014 as of Saturday. While this is slightly behind Mexico (1,065) and Canada (1,867) case counts, it’s a troubling trend as we edge closer to breaking a 25-year record.

"The North Dakota and Arkansas outbreaks (11 cases and 6 cases) and subsets of the Texas outbreak (the El Paso cluster is medium with 53 cases) are still small but continue to grow. We also had sporadic cases in California and New York the past week. Note: Florida stopped publicly sharing infectious disease alerts; it’s unclear why.

Figure by Your Local Epidemiologist

"Growth in other places, like West Texas, Oklahoma, and New Mexico, continues to slow down. This is due to a combination of two things:

  • In some places, the virus is running out of people to infect.

  • Local public health teams are actively tracing, isolating, quarantining, and vaccinating.

"What does this mean for you? You’re well protected if you’re up to date on your MMR vaccine. However, if you live near an outbreak and have an infant under 12 months, talk to your pediatrician—MMR can be given as early as 6 months in some cases. Slowing spread is welcome news for those most at risk, including immunocompromised individuals, infants under 1, and others who are unvaccinated.

"For the latest measles SITREP report, go here:

Ysph Vmoc Special Report Measles Outbreak Southwest Us 5 10 2025 [58] Read Only
2.53MB ∙ PDF file
Download

Two Food Safety Alerts

At least 10 people are sick from a Listeria outbreak in 4 states

"Fresh and Ready Foods has recalled several ready-to-eat sandwiches and snack items sold in California, Washington, Nevada, and Arizona—including in healthcare facilities—due to a Listeria outbreak. So far, at least 10 people have been hospitalized. Those most at risk include pregnant women, older adults, and people with weakened immune systems.

"The recalled products have “use by” dates between April 22 and May 19, 2025, and were sold under the brand names Fresh & Ready Foods, City Point Market Fresh Food to Go, and Fresh Take Crave Away.

Potential Salmonella vine-ripe tomatoes recalled in 11 states

"Ray & Mascari Inc. has issued a recall of 4-count vine-ripe tomatoes sold at Gordon Food Service Stores across 11 states. This is precautionary, as no illnesses have been reported so far, but salmonella was detected after routine testing.

"If you bought these and live in one of the affected states (see map above), it’s best to toss them out.


Good news! New York just became the 9th state to pass universal school meals.

"Last week, New York joined eight other states in passing universal school meals for children. (Many other states are planning, drafting, or discussing.) This is a public health victory, propelled by a silver lining of the pandemic, which increased awareness of the importance of school meals for children.

"Cost of this policy is a common concern—and some argue kids from wealthy families shouldn’t get free lunch—but the public health benefits are significant, including increased access to food for all, reduced lunch stigma, and less administrative burden. Research has been mixed on whether it universally improves attendance and test scores, but there are certainly some strong effects in some places and among specific groups.


Between the lines

"A lot is happening between the lines in the health policy world that isn’t necessarily getting picked up, so I figured I would call out a few that are unfolding:

1. Vaccine policy is stalling in an unusual way.

(Concern meter: Moderate)

"At the most recent ACIP meeting, CDC’s external vaccine advisory committee voted to expand RSV vaccine eligibility to adults aged 50 and older. Normally, this recommendation would be approved by the CDC Director within 48 hours. But since we currently don’t have a confirmed director (Dr. Monarez awaits Senate approval), the decision fell to the Chief of Staff. That was weeks ago—and still, no sign-off.

"Word is RFK Jr. has empowered his inner circle to privately access and review the science before making a decision, effectively bypassing the expert advisory process altogether. This delay and lack of transparency undermine the administration’s own stated commitment to transparent decision-making.

2. The Surgeon General nominee is… a wellness influencer.

(Concern meter: Low. Doing wonders for my impostor syndrome.)

"Casey Means, a physician-turned-influencer and founder of a wellness tech company, has been nominated for Surgeon General. While the role doesn’t drive policy, per se, it does come with a huge megaphone—it’s “America’s Doctor,” after all. Past Surgeon Generals have shaped public understanding of cigarettes, alcohol, and loneliness.

"While she rightly highlights important issues like nutrition, the solutions she promotes often lead Americans down the wrong path. For example, her company profits from selling continuous glucose monitors to the general public—despite strong evidence that these devices are only truly useful for people with diabetes who take insulin. (Note: The wellness industry is lucrative; worth more than $6 trillion.) She’s also questioned the number of childhood vaccines, advocated drinking raw milk during an H5N1 outbreak, and suggested unsafe practices like making Ozempic at home.

"But beyond these specific claims, what’s more troubling is what she represents: a growing trend of capitalizing on the failures of U.S. food and health policy by turning health into a consumer lifestyle brand. A movement often divorced from medical training, public health, and systemic reality—fueled by mistrust and the vacuum left by institutions slow to respond or evolve.

"Interestingly, the political response has been chaotic. MAGA influencers inside the White House, like Laura Loomer, are angry that Means is even being considered. Some in the MAHA movement think she’s too supportive of vaccines.

"I originally assumed her nomination would sail through. Now, I’m not so sure. Regardless, a wellness influencer getting a Surgeon General nomination is doing wonders for my imposter syndrome.

3. Eyes are on the RFK testimony

"RFK Jr.’s upcoming testimony on May 12 is mainly triggered by the Executive Budget released a few weeks ago. But I expect (and hope) he’ll be asked about far more than budget line items. The public deserves answers on several fronts: how proposed cuts will actually impact community’s health, his role—or lack thereof—in responding to the measles outbreak, lack of transparency, and more. Here’s what you can do if you’re concerned about health cuts.


Question grab bag

“I’m curious about what flu and Covid will look like next winter in places with high measles rates. If measles can wipe out a previous immune system, will Covid and flu look like novel viruses to those with a measles infection?”

"It’s a valid concern. Measles can cause “immune amnesia”—a relatively recent scientific discovery—where the virus erases existing immune memory, leaving people more vulnerable to other infections like flu and Covid. This can lead to a spike in all-cause mortality, even after someone recovers from measles. With years of underfunded research, we’re entering uncertain territory as cases rise, and it will be important to closely track what happens next.


Bottom line

"You’re all caught up! Have a wonderful week.

"Love, the YLE team"

Sunday, May 11, 2025

Dr Ruth's COVID & Health News, 5/11/25

Here's Dr Ruth Ann Crystal's latest impressive newsletter:

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COVID & Health News 5/11/25

"Similar to last week, acute respiratory illnesses like COVID, the Flu and RSV are low on a national level. Influenza B had been quite high in the Northeast, but it also has come down significantly. Human Metapneumovirus (HMPV) which causes cold-like symptoms is still descending in the Northeast and Midwest.

COVID

"SARS-CoV-2 wastewater levels are at LOW levels according to the CDC in most places in the U.S., as are Emergency Department visits for COVID and COVID deaths. JP Weiland estimates about 190,000 new COVID infections per day nationwide with 1 in 173 Americans currently infected as of May 9.

"In California, Vallejo had a large increase to 387 PMMoV of SARS-CoV-2 in wastewater, while the next highest levels according to WastewaterSCAN are Novato at 295 PMMoV and Palo Alto at 290 PMMoV. WastewaterSCAN is more current than the CDC reporting, but it omits 12 states’ data. CDC wastewater data is from a week ago.

SARS-CoV-2 Variants

"Right now, we are in a good place with low SARS-CoV-2 wastewater levels in most places in the US. The LP.8.1 variant continues to dominate and represents 70% of COVID cases in the US now, and newcomer XFC (also known as XFG) is at 9% of cases. NB.1.8.1 is growing quickly in Asia and has been shown to have both high ACE2 binding and significant immune escape according to a new study from Yunlong Cao’s lab. XFG (aka XFC) shows strong immune evasion, but has reduced receptor binding, suggesting it may require additional mutations to become more transmissible. Ryan Hisner explains the findings well in this thread.

Variants

From: https://covid.cdc.gov/covid-data-tracker/#variant-proportions
From: https://www.biorxiv.org/content/10.1101/2025.04.30.651462v1.full.pdf

Acute COVID infections, General COVID info

"A new study shows that SARS-CoV-2 nucleocapsid protein (NP) can transfer from infected cells to nearby uninfected lung epithelial cells, where it triggers antibody-driven complement attack. This immune response can damage uninfected cells, potentially contributing to the tissue injury observed in moderate to severe COVID infection. Higher anti-NP antibody levels were found in patients with lung abnormalities. Enoxaparin was found to block NP binding and prevent complement deposition.

From: https://www.cell.com/cell-reports/fulltext/S2211-1247(25)00283-9

"A new comprehensive review from Harvard explains how the SARS-CoV-2 spike protein enables viral entry into host cells and how mutations affect its function. It explores how structural changes in the spike protein contribute to immune escape and transmissibility of new variants with implications for vaccine and therapeutic design.

Fig. 2: A model for membrane fusion mediated by SARS-CoV-2 S protein.

From: https://www.nature.com/articles/s41579-025-01185-8

Vaccines

"Amid declining vaccination rates and rising outbreaks of preventable diseases like measles, Health and Human Services Secretary Robert Kennedy Jr. announced plans to require placebo-controlled trials for vaccines. Requiring new placebo trials for vaccine updates, such as yearly updates for COVID or flu, is unnecessary, unethical, and could result in delayed protection against evolving viruses. You wouldn’t test new seatbelts by leaving half of the passengers without one because it has been proven that they protect.

From: Marta Tufet, UnbiasedSciPod via BK Titanji

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"Moderna's phase 3 trial of a combined flu and COVID-19 mRNA vaccine in adults aged 50 and older showed strong immune responses and a safety profile comparable to separate vaccines. The combo vaccine elicited higher antibody levels against both viruses, suggesting potential for simplifying vaccination schedules. Regulatory approval is pending further efficacy data.

"A study using U.S. Veterans Affairs data found that the 2024–25 Pfizer COVID-19 booster was 68% effective against hospitalization, 57% against emergency or urgent care visits, and 56% against outpatient visits. Despite these findings, vaccine uptake was low, with only 3.7% of eligible individuals vaccinated by November 2024. Researchers recommend increasing booster coverage to reduce severe COVID outcomes.

"David Ho’s lab looked at the efficacy of the 2024-2025 mRNA COVID vaccine and found that "Serum neutralizing antibody titers against LP.8.1 were comparable to those against KP.3.1.1 and XEC, indicating that LP.8.1 is antigenically similar to its predecessors." So, this vaccine should work well against LP.8.1, the main variant in circulation now.

"A new review in Nature highlights the promise of nasal vaccines in preventing respiratory infections, including COVID. By stimulating mucosal immunity in the nose and upper airways and producing both IgA and IgG, these vaccines may offer faster and more effective protection at the site of viral entry.

From: https://www.nature.com/articles/s41586-025-08910-6/figures/1

Antiviral treatments

"A study from Spain found that each day of delay in receiving COVID antiviral medications increased the risk of hospitalization or death by nearly 18% for vulnerable patients. Patients with advanced age, comorbidities, or immunosuppression and mild to moderate COVID infection who received prescriptions directly from emergency physicians were treated faster and had better outcomes.

Long COVID

"In a multicenter Italian study, researchers used nailfold video capillaroscopy (NVC) to identify microvascular damage in Long COVID patients up to 18 months after infection. Long COVID patients had significantly more dilated capillaries, microhemorrhages, abnormal capillary shapes (neoangiogenesis) and lower capillary density than both recovered COVID patients without Long COVID and healthy controls. Comparing NVC images in patients who had NVC before COVID infection and after COVID infection confirmed new vascular damage following infection. Capillaries are important for all tissues including muscles and the heart to be able to extract oxygen from the blood. Endothelial injury may be contributing to Long COVID symptoms.

Figure 1

"Nailfold videocapillaroscopy picture of a control healthy subject (A), a recovered COVID-19 patient without Long covid (B) and two Long COVID patients (C and D). Black line shows 1 mm.

"Photo A (control healthy subject, male, 60 years old), normal capillary density (12 capillaries per linear mm), normal hairpin capillaries without dilations, microhemorrhages, or abnormal capillary shapes.

"Photo B (recovered COVID patient without Long COVID, male, 53 years old), dilated capillaries are highlighted by asterisks and capillary density is normal (9 capillaries per linear mm).

"Photo C (Long COVID patient without systemic sclerosis, male, 42 years old), two abnormal capillary shapes (neoangiogenesis) are highlighted by asterisks and capillary density is reduced (5 capillaries per linear mm).

"Photo D (Long COVID patient without systemic sclerosis, female, 39 years old), two dilations are highlighted by asterisks and capillary density is 8 capillaries per linear mm.

From: https://rmdopen.bmj.com/content/11/2/e005469

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"A new study from Rob Wüst’s lab found that patients with Long COVID and ME/CFS have distinct skeletal muscle changes not explained by inactivity or bed rest. Both Long COVID and ME/CFS groups showed reduced muscle oxidative capacity and altered mitochondrial function on muscle biopsy. Additionally, ME/CFS patients had greater impairments in muscle membrane excitability. “Patients with Long COVID and ME/CFS did not have muscle atrophy, but had less capillaries and more glycolytic fibers, none of which were associated with maximal oxygen uptake.” The authors conclude that Long COVID and ME/CFS have distinct biological muscle pathologies requiring targeted treatment approaches.

From: https://www.medrxiv.org/content/10.1101/2025.05.02.25326885v1.full.pdf

"The Schmidt Initiative for Long Covid (SILC) announced a clinical trial to be led by Dr. Nancy Klimas at Nova Southeastern University that will test AstraZeneca’s long-acting monoclonal antibody Sipavibart as a potential treatment for Long COVID. The randomized, placebo-controlled trial will enroll 100 participants to assess symptom improvement and residual spike protein presence. The study builds on earlier reports of Long COVID remission after monoclonal antibody use and aims to expand treatment options for millions affected worldwide.

"A systematic review and meta-analysis of nearly 140,000 participants found that excess weight and obesity are linked to increased risk of neurological symptoms in Long COVID patients including headaches, numbness/tingling, memory issues, vertigo and depression. Researchers suggest that fat tissue may serve as a reservoir for the virus, contributing to prolonged symptoms.

"A systematic review of 35 studies involving 4.4 million COVID patients found that 1.37% developed new-onset diabetes after COVID infection, a rate higher than the general population. Most cases were type 2 diabetes, and risk factors included severe COVID infection, hospitalization, and pre-existing health conditions. Researchers suggest monitoring COVID survivors for diabetes, especially those with risk factors.

"A prospective study found that 55 hospitalized patients recovering from COVID reported significantly increased symptoms of heartburn and acid reflux 3 to 6 months after hospital discharge. Biopsies revealed higher esophageal permeability under acidic conditions, increased IL-8 levels, and elevated expression of Claudin-2, a tight junction protein that weakens epithelial barrier function. These findings suggest COVID infection can cause long-lasting damage to the esophageal lining, potentially explaining persistent gastrointestinal symptoms in Long COVID.

Graphical Abstract

From: https://link.springer.com/article/10.1007/s10620-025-09062-3

"A preprint study from Mount Sinai found that 57% of Respiratory Long COVID patients with ongoing shortness of breath showed signs of heart and lung inflammation nearly a year after infection, even when standard tests were normal. Advanced imaging like PET/MRI and DECT revealed myocarditis, vascular inflammation, pulmonary infiltrates, and perfusion defects in a majority of patients. Blood tests also showed abnormal protein profiles linked to inflammation. These findings suggest that Long COVID can cause hidden cardiopulmonary damage, and advanced imaging like PET/MRI and DECT may be key to detecting and managing long-term risks.

Graphical Abstract

From: https://jnm.snmjournals.org/content/early/2025/04/30/jnumed.124.268980

"A preprint from Germany reports that 68 individuals with Long COVID had unusually active CD8+ T cells and elevated IL-3 levels, which may drive inflammation and symptom severity up to 18 months after acute COVID infection. These immune signatures could help identify patients at risk and guide development of targeted therapies.

"Using single-cell analysis, scientists in China uncovered widespread changes in alternative polyadenylation (APA) of mRNA in brain-related cells after COVID infection. These disruptions may contribute to neurological and psychiatric symptoms observed in Long COVID patients.

"Dr. Lindsay McAlpine of Yale recently announced an upcoming public forum on Long COVID pathogenesis on Thursday May 15 at 10:30am ET.

H5N1 Bird Flu

"According to CIDRAP, “University of Maryland scientists are calling for increased surveillance of avian flu in domestic cats after a global review of 20 years of published data reveals a dramatic uptick in feline infections—and the number of ways cats are being infected—after the emergence of H5N1 clade 2.3.4.4b in other mammals.” Experts warn that domestic animals could act as intermediaries, facilitating virus adaptation and increasing pandemic risk.

"The US government cut $160 million in funding to the UN’s Food and Agriculture Organization (FAO), shutting down 64 global health security projects, including bird flu surveillance in 51 countries. US farming and dairy groups warn that this move jeopardizes early warning systems that help protect American agriculture. More than 31 million birds in the United States have already been culled in 2025, triggering export losses, egg shortages and fears of human transmission.

Measles

"As of May 9, 2025, the United States has reported 1,001 confirmed Measles cases across 30 states with 13% of Measles cases being hospitalized, mostly in children, and 3 confirmed Measles deaths. Texas remains the epicenter with 709 measles cases, particularly concentrated in West Texas counties with low vaccination rates.

"The outbreaks are linked primarily to undervaccinated communities and international travel. Measles can be severe, causing high fever, rash, pneumonia, encephalitis and even death, particularly in unvaccinated individuals. The Measles, Mumps, and Rubella (MMR) vaccine remains the most effective prevention method. Herd immunity in a community requires over 95% vaccination rates, but vaccination rates have declined since the pandemic due to increased exemptions.

"About 180 unvaccinated students in Williams County, North Dakota, are under a 21-day quarantine after measles exposure was confirmed in three Williston schools, where four infected individuals were present while contagious. Health officials have identified nine total cases and declared a community outbreak highlighting low MMR vaccination rates among local kindergartners which have dropped below the 95% threshold needed to prevent spread.

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Other news

"In a study of over 2.2 million adults in South Korea, researchers found that people aged 50 and older who received the live zoster (shingles) vaccine had significantly lower risks of major cardiovascular events compared to those who were unvaccinated. The vaccine was linked to reduced rates of heart failure, stroke, ischemic heart disease, and arrhythmias, with the greatest benefits appearing 2 to 3 years after vaccination. The protective effect lasted up to 8 years and was especially strong among men, people under 60, those with unhealthy lifestyles, and those from low-income or rural backgrounds.

"Could a vaccine prevent the progression of Alzheimer’s disease? Researchers from New Mexico have made a tau-targeting vaccine called pT181-Qß which they tested in mice and in non-human primates. The vaccine triggered strong antibody responses, was safe, and reduced abnormal tau buildup while improving memory, motor function, and preventing brain shrinkage. These results support the potential of pT181-Qß as a future vaccine to treat tau-related neurodegenerative diseases like Alzheimer’s Disease.

"I recently took a picture of a bee pollinating a foxglove flower and when I looked at the photo afterward, I saw that another bee had flown and photobombed the shot.

"Happy Mother’s Day!

"Have a good week,

"Ruth Ann Crystal MD"

Measles Stats: Don't Blame RFK Jr. For Your Own Stupidity

From NPR 5/9/25: "Measles math: What to know about 1,001 measles cases across the country"
May 9, 20252:14 PM ET

By Maria Godoy, Pien Huang, & Diane Webber

"The Centers for Disease Control and Prevention reports there have been 1,001 confirmed measles cases in the U.S. this year. It's the second-highest case count in 25 years, topped only by 2019, when more than 1,200 measles cases were detected. The best way to contain measles is two doses of the MMR vaccine (measles, mumps and rubella).

"Here are numbers to help you understand how measles is spreading now.

"The CDC keeps track of confirmed cases and is updating its count on a weekly basis. On May 2, it reported 935 cases. On Friday, it reported cases have ticked past the thousand mark, to 1,001.

31 jurisdictions:

"Measles cases have been reported in 31 jurisdictions, up from 30 on May 1. Cases have been reported in more than half of U.S. states this year, but not all of those states have full-fledged outbreaks.

14 outbreaks:

"An outbreak is defined as 3 or more related cases. So while the total number of cases is important, the number of outbreaks shows where the virus is spreading. The number of outbreaks went from 12 last week to 14 this week.

"By far the largest outbreak is centered in west Texas, where measles has been spreading since January. Reported cases in that outbreak totaled 683 last week and 709 this week.

3 deaths

"Two unvaccinated, otherwise healthy children in Texas have died of the disease. One adult in New Mexico was diagnosed with measles posthumously.

18 people

"In a population where no one is vaccinated, a single person sick with measles could go on to infect up to 18 others on average. By comparison, when 82% of a population is vaccinated, a sick person would infect about 2 to 3 other unvaccinated people on average.

95% vaccination rate

"To prevent outbreaks from spreading within a community, there needs to be a vaccination rate of 95%, according to the CDC. Below that threshold, a community's herd immunity can begin to erode. In Gaines County, Texas, the epicenter of the outbreak in that state and where measles is still spreading, the kindergarten vaccination rate against measles is just under 82%.

"Herd immunity means that enough members of a community are immune to a contagious disease that it is unlikely to keep spreading because there aren't enough people vulnerable to infection. Herd immunity protects people with weakened immune systems and children who have not yet completed their two-shot series of the measles vaccine.

12 months

"It's an open question how long measles will keep spreading in the U.S. The Texas outbreak, the biggest one, began in January. If any single outbreak continues to result in ongoing transmission for more than 12 months, the U.S. will lose its measles "elimination" status. That's a technical term in public health for contagions that have been well-controlled for 12 months or more. The U.S. has had that status for about 25 years."