Cumulative Confirmed COVID-19 Cases

Tuesday, April 30, 2024

Can You Stop Calling Them "Students" Now?

New York Post:  Violent pro-terror rioters shouting ‘Intifada!’ smash their way into Columbia University academic building in latest campus chaos

"A huge mob of masked pro-terror rioters broke into an academic building at Columbia University and seized it early Tuesday — rebranding the iconic hall named after founding father Alexander Hamilton and draping it with a giant flag calling for “intifada.”

"Dozens stormed into Hamilton Hall and sealed themselves in shortly before 1 a.m. — with some using metal barricades, chairs and tables to block others from getting inside, footage posted on social media shows.    

"One shocking video captured a hammer-wielding demonstrator smashing through a glass-paneled door and placing what appeared to be a bike lock around its handles.

"Another clip showed a group roughing up a student who had tried to block anarchists — including some brandishing “Intifada” signs — from getting inside the building.   

"Once inside, some anti-Israel protesters quickly covered security cameras black trash bags and tape, according to the student-led Columbia Daily Spectator."

---------

These are terrorists, Hamas sympathizers, and Jew-haters. These are not "students" or "protesters". They are not at all intimidated by Columbia's feeble attempts to stop them. The National Guard should be brought in ASAP before someone is killed.

The names of  these pro-Hamas collaborators should be put on a blacklist so they won't be entitled to the good jobs their colleges hope they get, but which they don't deserve. They should think of it as  "quiet quitting" in advance.

I'm sure we'll soon be treated to more Biden lectures about "Islamaphobia.  But you don't see college campuses full of Jewish students screaming "Kill Arabs", do you?

COVID Update from Your Local Epidemiologist

In her latest newsletter, Dr Katelyn Jetelina discusses A Covid-19 update: More data is sunsetting, new low in hospitalizations (!), and the upcoming fall vaccine formula.

"It’s been a while since a Covid-19 update. Some major developments are coming down the pipeline. Here is an attempt to keep you updated, even if it’s not making headlines.

Hospitalization reporting is sunsetting.

"During the Covid-19 emergency, the U.S. scrambled to get a national view of severe disease quickly due to our fragmented healthcare system. We eventually created a national hospitalization reporting system where hospitals were required to report capacity, Covid-19 hospitalizations, and more.

"This was an enormous step because it led to visibility and, thus, action. This system could be used for many things today and in the future (cough, cough, H5N1). Preparedness is the name of the game; we cannot slip back into the cycle of panic and neglect.

"Unfortunately, this hospital reporting requirement is sunsetting today (April 30). Sunsetting means a few things:

  • Hospitals will voluntarily send data. Given that hospitals hated sending Covid-19 hospitalization data in the first place, I assume that many will stop.

  • We will rely heavily on our older system, which is suboptimal. In pre-pandemic times CDC created a hospital surveillance system called RESP-NET for flu and other diseases. This system is great but only collects data from about 10% of hospitals, mostly from urban areas. So, this data shows an incomplete and sometimes biased picture. Take this winter, for example, where RESP-NET (the older system) showed flu hospitalizations higher than Covid-19; however, this was not the case when looking at data from the newer, more complete reporting system.

Data Sources: CDC; Annotated by YLE
  • HHS is not giving up the fight. In a welcome development, the Department of Health and Human Services (HHS) has proposed a new rule requiring hospitals to report data outside of an emergency. The new rule’s proposed start date of October 1.

HHS is asking for public comment starting May 2, particularly whether you think this new rule is important. (My humble opinon: It’s an essential system that will protect the health and safety of our communities.) I’ll alert you once it’s open. Your comments will really make a difference.

Covid-19 is at a new low, with variants on the horizon. 

"Covid-19 in wastewater is at very low levels at this time, which is a welcome reprieve after this respiratory season. This means the probability that Covid-19 is hanging around at a party or daycare is very low.

SARS-CoV-2 Wastewater (Source: CDC)

"With it, hospitalizations are at the lowest point since the beginning of the pandemic. What a beauty to see!

Source: CDC; Annotated by YLE

"SARS-Cov-2 continues to mutate. The next variant on deck is what scientists call “FLiRT,” shorthand for two mutations on the spike protein. Think of these as the children of JN.1.

"Will this cause an infection wave? There are many similarities between FLiRT and JN.1—which took over this winter—so this certainly won’t cause a tsunami and probably not even a wave. Maybe a wavelet, depending on how much immunity our communities have. A smaller summer wave would follow a pattern we’re seeing, where each summer wave gets smaller and smaller over time. (See figure above.)

Many of you are asking whether you should get your spring Covid-19 vaccine. My thoughts are on a previous YLE post here, but basically, if you’re over 65 and high risk (i.e., in a nursing home, or have comorbidities), I would. I would also get this sooner rather than later. You don’t want to get your spring vaccine too late, because a fall vaccine will be coming in a few months. We want these spread apart as much as possible.

WHO recommended a vaccine formula for fall. FDA will decide May 16. 

"WHO recommended a JN.1 formula for the upcoming fall Covid-19 vaccine. Their spring recommendation (including for flu) is an effort to get the global players (i.e., countries and manufacturers) on the same page.

"JN.1 is the most recent Covid-19 variant that spread this past winter. Many scientists (including myself) are disappointed because this means we are following the virus instead of getting ahead of it.

"The FDA will decide the U.S. vaccine formula plan on May 16. They will likely follow WHO, especially since Novavax has already tested this formula in anticipation of the fall rollout. Protein-based vaccines need a much longer development runway than mRNA vaccines.

"I’ll share Cliff’s notes from the May meeting.

Bottom line

"Things should be quiet on the Covid-19 front for now. I hope you get to enjoy those graduations and summer vacations!

"Love, YLE"

----------------

I'm disappointed but not surprised about the end of the hospital reporting.  Once again we'll be left in the dark.  Whenever there's a lull like we're having, I instinctively worry and wait for the other shoe to drop. That other shoe is probably the FLiRT mutation as well as JN.1 and JN.2

Better to be vigilant than be in denial.

Monday, April 29, 2024

Biden: An Ally in Name Only

Yet another sickening betrayal of Israel by their supposed "ally", the United States of America. I'm sure this news will further gratify & inspire the student terrorists who are inciting hatred and violent towards Jews on campus these days, as well as emboldening Hamas even more:

Biden admin accuses Israeli military of human rights violations in stunning condemnation
State Department finding comes as anti-Israel protests sweep college campuses

"The U.S. found five units of the Israel Defense Forces responsible 'for individual incidents of gross violations of human rights,' the State Department announced on Monday – though whether funding to the American ally could be cut over such abuses under the so-called 'Leahy Laws' still hangs in the balance. 

"At a press briefing, State Department principal deputy spokesman Vedant Patel told reporters that the human rights violations happened all before the Oct. 7 attacks by Hamas militants on southern Israel and none happened in Gaza. Four of the units have 'effectively remediated,' he said, while the U.S. continues 'in consultations and engagements with the government of Israel' on the remaining unit."

--------------

Meanwhile, these collegiate terrorist thugs are demanding they not be held accountable for their actions in these anti-Israel protests and want amnesty!  "At issue is whether universities and law enforcement will clear the charges and withhold other consequences, or whether the suspensions and legal records will follow students into their adult lives."

Well, these ugly brats should have thought about that before they decided to put those shmattes on their heads and attack Israel and Jewish people!  

I have absolutely no sympathy for them whatsoever and hope they have to live with the results of their hateful, evil acts.

Sunday, April 28, 2024

Blaming COVID For Jew-Hatred!

This is the most ridiculous excuse for vicious antisemitism that I have ever heard in my life, and anyone who believes this just wants to blame everything but the antisemites themselves:

COVID shutdowns, isolation to blame for pro-Palestine protests, experts say 

"Blame it on Covid.

"Campus protesters roiling colleges across the nation are part of a generation shaped by the pandemic, who grew up isolated and angered by school shut-downs and social distancing and are desperate to find a connection, community and a voice, experts told The Post.

"The pro-Palestinian cause allows discontented youth to express 'long-withheld rage,' said forensic psychiatrist Carole Lieberman. It gives them an 'opportunity to identify with the ‘oppressed’ against ‘oppressors.'

“'People who offer an escape from this confusion, by promoting a direction they claim will lead to happiness and purpose, have found a hungry audience,' said Lieberman, a California-based trial expert witness.

:"Protests and encampments ostensibly 'in solidarity' with Palestinians have ramped up in the past week, starting with embattled Columbia University and stretching as far as Texas and Atlanta. Jewish students have reported feeling harassed and unsafe on campus as protesters chant things like, 'From the river to the sea, Palestine will be free'

"It appears the young demonstrators don’t have a full understanding of the movement they’ve aligned themselves with, Lieberman said."

------------------------

There's more, but I can't stand any more of this gobbledegook and the attempts to erase the consequences for these spoiled bigmouths. So in other words, calls to "Gas the Jews" and "Kill the Jews" is only because you didn't like the COVID lockdowns. I hope they make sure to mention this excuse at their future job interviews.

Funny - millions of us also went through that first year, and we're not out blocking traffic, terrorizing Jewish people, protesting instead of going to school, and acting like Nazis.

A Titanic Sale

Gold pocket watch recovered from the body of the richest man on the Titanic who went down with the doomed ship after seeing his pregnant wife into a lifeboat sells for more than £1MILLION

"The pocket watch of the richest man on the Titanic – recovered when his body was fished out of the Atlantic seven days after the tragedy – was sold a record-breaking £1.175 million yesterday.

"The timepiece belonged to John Jacob Astor IV, a US business magnate who was among more than 1,500 people who died when the ship struck an iceberg in the early hours of April 15, 1912.

"His 14-carat gold Waltham watch was sold at Henry Aldridge & Son auction house in Wiltshire for a record-breaking £1.175 million, six times the guide price, matching the record paid for a Titanic artifact – the violin played by bandmaster Wallace Hartley."

----------------

I've been fascinated by the tragic story of the Titanic ever since I read Walter Lord's "A Night to Remember" at age 12. The movie version of the same name starring Kenneth More was the most realistic portrayal  I've seen, but I hated the James Cameron film.

Robert Ballard's 1985 discovery of the wreck of the Titanic was something I never expected to see.

Saturday, April 27, 2024

Doctor of Quackery

Unbelievable that a doctor would say something this idiotic and cause gullible people to take their masks off.  But this is Dr Joseph Ladapo of Florida, and he has said many ridiculous things. He needs his medical license revoked so he can practice as a Doctor of Quackery instead.

Joseph Ladapo says mask wearers ‘just like to hide their faces’

"The state's leading doctor has a provocative theory about people still wearing masks.

"Florida’s Surgeon General is continuing to evangelize against mask wearing like it’s 2022.

"His latest theory?

"People wearing protective coverings over their faces simply don’t want to be seen, said the state’s Chief Health Officer and doctor of medicine at the University of Florida.

"Surgeon General Joseph Ladapo said a doctor at the University of California Los Angeles talked to 'some of her medical residents, physicians in training who are wearing masks and it turns out it seems like some people, they just like to hide their faces, which is a really sad testament to humanity and where we are right now with just how people have dealt with all the stress and all the social media disconnection and all the craziness.'

"'But part of the reason seems to be that some people like to hide their faces,' Ladapo added on the Clay Travis and Buck Sexton Show.

"'Obviously, some people are still afraid and think that masks are going to help them, which is total nonsense. And that’s really sad. But there is this phenomenon now, it seems where people are trying to hide.'

"Ladapo continued along this theme throughout the interview, noting that in California 'people are still masking in hospitals' and that Uber drivers are 'still masking.'

"Ladapo was Gov. Ron DeSantis’ second Surgeon General, brought in to replace Scott Rivkees, who was deplatformed by the state of Florida (but still retained on the payroll), after Rivkees suggested in 2020 that people may need to socially distance for the foreseeable future."

The Latest Pronouncement on Israel from The White House

How's this for the latest in absolute gall from the White House?

Breitbart: White House: ‘Not Clear’ Israel Can Have Rafah Offensive Plan That Would Satisfy Us

"On Friday’s broadcast of MSNBC’s “Andrea Mitchell Reports,” White House National Security Adviser Jake Sullivan stated that it’s “not clear” that it’s even possible for Israel to have “a credible plan” for an invasion of Rafah that the White House would support.

"Sullivan said, “[W]e have made clear that our policy in Gaza will be determined by the steps Israel takes, both with respect to facilitating humanitarian assistance that can save lives, and with respect to civilian protection as it conducts its operations. We have also made clear our absolute deep and fundamental concern about a major military operation in Rafah, because we believe, first, it’s where the aid is coming in. And if you cut that aid off, it makes it more difficult to feed and house people. Second, as you said, it’s where more than a million people are sheltering because they’ve been progressively moved there as Israel has continued its campaign. And it’s not clear to us that there can be a credible plan for where they go to have shelter, housing, medicine, and all of the things that they need. So, we continue to express our concerns publically and privately to the Israeli government. I have dealt with them directly on this issue. And we will continue to do that. I don’t want to get into the details of sensitive diplomatic conversations. I would just say, the U.S. position on this issue remains clear. And Israel understands where we are coming from.”

"He added, “[W]e are going to continue to make our decisions based on what he believes is in the best interests of the American people and is most consistent with American values. That is what is guiding him today and it will guide him always through the remainder of this conflict.”

--------------------

Translation of headline: "White House: Not Clear Israel Can Commit National Suicide Fast Enough For Us Before The Election". 

Unbelievable. Just who do Jake Sullivan, Biden, and Blinken think they are?  The way they talk, you'd think ISRAEL had committed the October 7 massacre against Gaza!  Too bad they don't ever criticize Hamas for stealing the food and other aid that Israel doesn't even have to provide them! And it's too bad that the White House never criticizes Hamas itself, the way it constantly criticizes Israel.

Israel does have a "credible plan". They plan to enter Rafah, get the job done, and stop answering to Biden! Israel is trying to eradicate the threat from Hamas and protect the Jewish people. If the White House isn't "satisfied", tough!

The New Hitler Youth

Terrorist threats like this against the Jewish people are not only cheered, they are tolerated and accepted, unlike the universal condemnation after George Floyd and the constant DEI training as a result.

I keep thinking of the trauma that Holocaust survivors and their children must especially be suffering when they see these threatening signs and hear the echoes of Hitler.

From the UK Daily Mail: Columbia bars Gaza encampment activist who said 'Zionists don't deserve to live' and discussed beating them to death...four months after holding disciplinary over his vile remarks

Big deal!  It's too little, too late. This "activist" is a celebrity now and is not going to stop. Thousands of antisemites are following his lead. Notice how they are now using the word Zionists rather than Jews? It doesn't fool us.

I'm waiting for the campus cries of "Sieg Heil!" and the bonfires of Jewish books next.

Friday, April 26, 2024

No Consequences for Jihadists

The campus Nazis get bolder by the day:

Hezbollah Flag at US College Protest Sparks Fury

"The flag of Hezbollah, designated a terrorist group by the U.S. government, has sparked fury across social media after it was displayed at a pro-Palestinian protest at Princeton University this week.

"On Thursday, Myles McKnight, a former Princeton student, shared a photo on X, formerly Twitter, showing demonstrators with the banner of the Shi'ite armed militia and political movement based in southern Lebanon. 'At @Princeton, Hezbollah flags,' the post said.

"The Hezbollah movement has long been aligned with Iran, and a key part of the informal "Axis of Resistance" grouping fighting against Israel and the U.S. across the Middle East. The group has been involved in constant cross-border skirmishes with Israeli forces since Hamas' October 7 infiltration attack and the subsequent offensive by Israel into the Gaza Strip.

"According to the Daily Princetonian, the independent student-run newspaper at the university, organizers of the protest at the college said that they asked the flag to be put away immediately after recognizing it."

----------------------

Why aren't these Nazi encampments being shut down? Where is the FBI and the Department of Homeland Security?

According to its website, Homeland Security has certain core values, and one of them is this:

"'Guarding America'. We will relentlessly identify and deter threats that pose a danger to the safety of the American people.  As a Department, we will be constantly on guard against threats, hazards, or dangers that threaten our values and our way of life."
 
Really?  Well, obviously DHS is disregarding their own values, as the anti-Jewish, anti-American, anti-Israel protests constitute a threat to this country, and especially to Jewish Americans!

What are they waiting for?

Thursday, April 25, 2024

Hitler Youth on Campus

It figures that the Babylon Bee would get right to the heart of the anti-Israel, anti-Jewish, pro-Hamas rallies on our college campuses:

Columbia Switches To Online Classes So Jewish Students Can Participate From The Attics Where They Are Hiding

And unlike Anne Frank, I do not think that these venomous people "are really good at heart". They are too filled with rage and hate. You can't change the minds of losers who somehow make it to college saying things like "Gas the Jews", "Send the Jews Back to Poland", and "Hamas, We Love You". What subject do they major in, antisemitism?

What next, shouting "Sieg Heil" in unison, or whatever the Hamas & Al Qaeda versions are?

The college presidents have lost control and are actually negotiating with the terrorist-sympathizers rather than having already had the National Guard physically remove them. You don't negotiate with terrorists -- or with their collaborators.

All I know is, Hamas is loving every minute of this shanda, while Jewish people worldwide are traumatized yet again.

Dr Topol on Bird Flu

Here's a recap of bird flu news from Dr Eric Topol as of April 24, 2024: 

A Bird Flu H5N1 Status Report. Updates from a joint USDA, CDC, FDA Joint Briefing Session Today

After weeks of being in the dark, it was good to see these 3 public agencies come together this morning to give a closed briefing (yes, open would have been better) and answer key questions about avian flu spread among cattle.

Here are the key points:

  1. Confirmation of H5N1 infected dairy cattle herds in 8 states. But the FDA report yesterday of commerical milk PCR positivity strongly supports that the cattle spread is far wider than these 8 states. Important to emphasize that (PCR) is testing for remnants of virus, not live virus, which would be unlikely with pasteurization. Other tests, assessing potential evidence for any live virus (egg viability and culture), are to be reported by the FDA going forward. Limited culture tests are all negative to date for any live virus in milk.

2. From the great work of U Arizona evolutionary biologist Michael Worobey who (heroically) analyzed the 239 H5N1 sequences that were released Sunday night for the first time, it was likely a single initiation of transmission from bird to cows. USDA stated they believe the outbreak in dairy cattle in the US began in late 2023, initially in Texas.

 

3. There is confirmation from sequencing of cattle to cattle and cattle to poultry back transmission. Also there is confirmation of asymptomatic dairy cattle with H5N1 infections but the extent of testing is unclear. The cows that have been infected appear to have a mild illness lasting about 2 weeks with discoloration of their milk. More information on the natural history of illness in cows and the proportion who remain asymptomatic are needed. The only documented human case to date was a dairy worker through direct contact that resulted in conjunctivitis.

4. For the readiness plan in case human transmission does occur, the public officials asserted that Tamiflu would be effective and it has been stockpiled, that gearing up testing would be done and, if necessary, the US could fully shift its annual flu vaccine production to make H5N1 shots at scale. They have 2 candidate H5N1 vaccines in hand that are well matched to the current sequence and there is the possibility to augment vaccine supply via mRNA-nanoparticle production. Nicely summarized by Helen Branswell at STATnews here

It appears very unlikely, but the more the H5N1 is spread unchecked, the bigger the reservoirs and chances for further functional mutations to take hold. So better to plan for a worst case scenario

5. A Federal order was put out this morning to mandate testing and reporting of cattle infected, measures to avoid further spread.  

6. Routine testing of pigs, which is important due to their potential facilitation of spread to humans, has been negative to date. Also to note, data we have so far are based on dairy cattle; little is known or available about beef cattle (which often cohabitate), but occupational exposure notifications have been put out to dairy farms and slaughterhouses

Although originally posted electronically several days ago, this front page article at LA Times today is a good background summary.

A snippet: “It has also proved especially deadly among some communal mammals, such as elephant seals and sea lions in South America, as well as caged fur-farmed animals in Europe. Nevertheless, outbreaks among dairy cows have come as a rude shock.”

As more information becomes available, I’ll update this post. In the meantime, seeing unity among the public health agencies is a good sign that we’re moving past the “opaque” era of the unprecedented bird to cattle outbreak here and finally seeing forthright communication to scientists and journalists— the way it should and needs to be.

Wednesday, April 24, 2024

PM Netanyahu’s Statement on US Campus Antisemitism

This statement by Netanyahu about the campus Nazis and Hamas collaborators is the one the White House should have given, instead of "Don't"-like wishy-washy remarks. I guess the Hamas vote is more important than protecting Jews in America.

------------------

PM Netanyahu’s statement on US Campus antisemitism.

“What’s happening in America’s college campuses is horrific. Antisemitic mobs have taken over leading universities. They call for the annihilation of Israel. They attack Jewish students. They attack Jewish faculty. This is reminiscent of what happened in German universities in the 1930s. It’s unconscionable. It has to be stopped. It has to be condemned and condemned unequivocally. But that’s not what happened. The response of several university presidents was shameful.

"Now, fortunately, state, local, federal officials, many of them have responded differently but there has to be more. More has to be done. It has to be done not only because they attack Israel, that’s bad enough, not only because they want to kill Jews wherever they are, that’s bad enough, it’s also when you listen to them, it’s also because they say not only, ‘Death to Israel. Death to the Jews,’ but ‘death to America.’ And this tells us that there is an antisemitic surge here that has terrible consequences.

"We see this exponential rise of antisemitism throughout America and throughout Western societies as Israel tries to defend itself against genocidal terrorists, genocidal terrorists who hide behind civilians. Yet it is Israel that is falsely accused of genocide, Israel that is falsely accused of starvation and all sundry war crimes. It’s all one big libel. But that’s not new. We’ve seen in history that antisemitic attacks were always preceded by vilification and slander, lies that were cast against the Jewish people that are unbelievable yet people believed them.

"Now, what is important now is for all of us, all of us who are interested and cherish our values and our civilization, to stand up together and to say enough is enough. We have to stop antisemitism because antisemitism is the canary in the coal mine. It always precedes larger conflagrations that engulf the entire world.

"So I ask all of you, Jews and non-Jews alike, who are concerned with our common future and our common values to do one thing: Stand up, speak up, be counted. Stop antisemitism now.”

Julia Doubleday at The Gauntlet on COVID - 4/24/24

 
Here's another information-packed  column by Julia Doubleday at The Gauntlet:

The WHO's claim that COVID wasn't airborne cost millions of lives. Now, they're changing the definition of airborne.  The story of how incorrect science became the basis of the global COVID response is the biggest scandal you never heard about.

The WHO is patting itself on the back this week.

After two years of argument and discussion, it has officially rebranded airborne viral transmission as “through the air” transmission. Airborne particles aren’t aerosol anymore; they’re “Infectious Respiratory Particles,” or IRPs. Jargony language aside, the major practical implications of this document are that, unlike previous airborne infection control guidance, their new guidance will not, in fact, control airborne infections. 

Let’s back up. To understand where we are, we have to understand how we got here.

In early 2020, the WHO had already decided COVID was not airborne. On March 28, 2020, they tweeted a famous and famously still-not-deleted fact check proclaiming this loud and clear. “FACT: #COVID19 is NOT airborne. The #coronavirus is mainly transmitted through droplets generated when an infected person coughs, sneezes or speaks,” the tweet reads, going on to recommend disinfecting surfaces, staying 1m distance from others, washing hands, and not touching your face. It’s accompanied by a graphic that looks like it was made in 20 minutes by an unpaid intern, which again affirms that COVID IS NOT AIRBORNE. All of the information in this short tweet is incorrect.

It also informed the global COVID response from top to bottom, making elimination of the virus impossible as governments implemented an inadequate protocol for stopping the spread.

From the beginning, the WHO was promoting a now-disproven model of infectious disease control centered on an artificial distinction between diseases transmitted by “droplets” - meaning large particles emitted while coughing and sneezing which quickly fall to the ground- and “aerosols” - meaning smaller particles that are emitted simply by breathing that can hang in the air like smoke. The best layman’s summary of the droplet vs. airborne scandal can be read here, in Megan Molteni’s thorough piece “The 60-Year-Old Scientific Screwup That Helped Covid Kill”, published at Wired in May of 2021.

Molteni’s piece follows a small group of intrepid scientists- Linsey Marr, an aerosol expert, Lidia Morawska, an atmospheric physicist, Yuguo Li, an indoor air researcher at the University of Hong Kong, and Katie Randall, an infectious disease historian, as they attempt to convince the WHO and other health institutions to take airborne spread of COVID seriously. In the process, they dig into the deep roots of scientific misinformation that led to the creation of the droplet vs. airborne dichotomy; incredibly, there was never any strong evidence to indicate that most viruses were spread via heavy “droplets” that fall to the ground. It was quite simply a creation of convenience predicated on poor assumptions, misinterpretations, and conflations. I recommend reading the whole piece, but in essence, institutions have been believing what they wanted to believe about airborne transmission for a long time.

It should also be noted that the institutional and financial motivations for failing to acknowledge airborne transmission of COVID and other viruses are pretty straightforward; it is, quite simply, far more expensive to implement proper infection control protocol for a virus that spreads through the air because a human is breathing than it is to implement infection control protocol for a virus that spreads when someone sneezes on you.

This paper, titled “Coronavirus Disease 2019 and Airborne Transmission: Science Rejected, Lives Lost. Can Society Do Better?” and co-authored by Morawska, provides an inside look at the WHO’s refusal to contend with scientific evidence, their allergy to all discussion of airborne transmission, and their dismissive, rude and stubborn behavior as aerosol experts came together to try and correct their incorrect guidance as COVID gained ground. “We alerted the World Health Organization about the potential significance of the airborne transmission of SARS-CoV-2 and the urgent need to control it, but our concerns were dismissed,” affirm the authors, going on to discuss their formation of the so-called Group 36:

On 29 March [2020], Morawska drafted a message in the form of a petition to the WHO director general (DG) and compiled a list of experts—colleagues of high international standing from around the world—whom she knew had been working on airborne transmission for many years from various angles, including aerosol physics, virology, public health, clinical medicine, infection prevention and control, building engineering, and facility management. She had worked on this broad topic over the years with several of these individuals. The next day she contacted all of the identified experts, explaining the problem, presenting the draft, and asking if they would like to support the petition. Every one of them did so, and some suggested names of additional experts to include. The list expanded to 36 names, a sizable group; although we knew that many more experts could have been enlisted given more time this was a manageable group who represented a breadth of expertise from around the world. This is how “Group 36” was born.

The WHO did not respond well to this petition, which again, was signed by the foremost experts in airborne transmission. Multiple meetings yielded nothing but irritated dismissal on the part of WHO, with participants recalling:

We were backed into a defensive position during the call, while we tried to make our points. After the call was finished, disappointed and frustrated, we wondered, Why are they acting like this? Why are they so bluntly rejecting our arguments?

Email correspondence between the two groups- the WHO and the aerosol expert petitions- is attached to the paper. The correspondence shows that the WHO either failed to grasp or represented themselves as failing to grasp the points made by the aerosol experts. Multiple times, they repeat false claims about how sure they are that COVID is spread via “droplets”, that respirator-style masks only need to be worn during AGPs (aerosol-generating procedures, an incorrect claim that is still repeated by medical practitioners today), and that fomites are a significant source of COVID transmission (they are not). They also repeatedly make arguments from authority, pointing to individuals who agree with them while refusing to engage with the science itself. In one impressive piece of circular logic in an email dated April 11, 2020, the WHO states:

To our knowledge and after careful review, available evidence on SARS-CoV-2 supports that the predominant route of human-to-human transmission of this virus is through respiratory droplets and/or contact routes. We note that also guidance from CDC, ECDC, and many other organizations all state that the mode of transmission of COVID-19 is primarily respiratory droplets and contact.

In this excerpt, the WHO cites the guidance of other organizations which are turn following WHO guidance. They cite no studies to shore up their claims that COVID must be spread via droplets, but sneeringly point out that the aerosol scientists have not produced “peer reviewed” studies demonstrating airborne spread. In April 2020, of course, it was impossible for any peer review to have been completed concerning a virus that was then a few months old.

Throughout the debate between the powerful WHO players and the upstart aerosol experts, the threshold of “proof” for airborne spread was unreachably high, while the threshold of “proof” for droplet spread was nothing at all. WHO continually states that they know COVID is spread via droplets while failing to address any of the actual scientific content of the petition from Group 36.

The work of these scientists, along with dozens of others, led to the groundbreaking realization that all common respiratory viruses- colds, flus, RSV, etc- are being spread in a manner that would have formerly fallen on the “airborne” side of the false airborne/droplet dichotomy. Hence the need to rethink the terminology entirely- and common infection control practices.

Once this was established, we stood at the precipice of a new era of disease control; imagine a clean air revolution in daycares, drastically cutting down the now-spiking rate of childhood illness. But three years after Molteni’s rundown was published, most medical institutions and government bodies are still practicing and recommending droplet infection control measures for COVID. What happened?

First, there’s been a lack of consistent, public communication. Today, most of the public still uses the mental model of “droplet” spread to understand COVID transmission- and that includes doctors and administrators in medical settings. Measures like social distancing, handwashing, wiping surfaces, and wearing surgical masks (not respirator style masks that form a seal) are insufficient to control the spread of COVID-19; some of them are out-and-out pointless. While things like surgical masks and distancing do reduce likelihood of transmission somewhat- not entirely- fomite transmission of COVID has never been documented and surface disinfection is wholly irrelevant to spread.

The failure to loudly communicate that our global health organizations were devastatingly wrong about something they stated with a high degree of confidence is perhaps unsurprising. That their claims led to 20-30 million deaths and counting, all the more so. In order to correct all the misinformation that the public, doctors, hospital administrators, health bodies and public officials absorbed during the full-court press to mitigate COVID with insufficient droplet measures, the WHO would need to loudly and publicly repeat that all their prior guidance was wrong. Not only that, but it was wrong because they lied; it’s true that they seem to have really believed their own misinformation, and in that sense, they approached the conversation honestly. But it was a lie to say they had proof, that they knew beyond a doubt, that COVID was not airborne.

Take WHO’s new Chief Scientist Jeremy Farrar’s comments this week, for example. He states:

In January, in February, in March, in April of 2020, the certainty of the scientific evidence compared to six months later, a year later, now, four years later, April 2024, is completely different.

In his defense of the WHO’s declaration that COVID was not airborne, he is here pointing out that the scientific evidence was uncertain. That’s true; it’s also why it was so irresponsible to present the claim “COVID is not airborne” with a high degree of certainty. A responsible body would have said “we are debating this, we don’t know, and the precautionary principle dictates that we should implement airborne infection control until we do.” Instead, they tweeted a graphic with a big INCORRECT stamp over the correct statement “COVID is airborne.” Not the language of an uncertain body communicating uncertain science.

The WHO, rather than demonstrate humility and contrition in the face of a world-circling failure that sent us down an infection control dead-end, continues to double down on excusing itself. That brings us to their newest attempt to both exculpate themselves and give governments and medical practitioners all over the world license to continue refusing to implement airborne infection control, endangering patients and citizens: this dry-sounding document, “Global technical consultation report on proposed terminology for pathogens that transmit through the air.”

Not everything in the document is terrible. On the plus side, the WHO finally invited subject matter experts like Linsey Marr to the table. They also were correct to eliminate the false dichotomy between airborne and droplet spread; as it turns out, viruses that spread via respiratory particles are contained in both large droplets and smaller aerosolized particles that can travel far beyond the arbitrary 6-feet range of the social distancing era. But this is where the positives end.

Instead of finally acknowledging that, since all these aerosolized viruses can spread in a manner consistent with what was formerly called “airborne” transmission, “airborne” infection control measures are required to control them, the WHO attempts to have its cake and eat it too by simply reimagining what infection control is supposed to accomplish. Instead of ensuring that patients will not be exposed to viruses in medical settings, the WHO is now encouraging medical practitioners to simply follow their hearts when it comes to the spread of COVID and other viruses. Is it an airborne “vibe”? Is it more of a “droplet” vibe? Whichever suits, take your pick!

From their paper:

There is NO suggestion from this consultative process that to mitigate the risk of short-range airborne transmission full ‘airborne precautions’ (as they are currently known) should be used in all settings, for all pathogens, and by persons with any infection and disease risk levels where this mode of transmission is known or suspected. But conversely, some situations will require ‘airborne precautions’. This would clearly be inappropriate within a risk-based infection prevention approach where the balance of risks, including disease incidence, severity, individual and population immunity and many other factors, need to be considered, inclusive of legal, logistic, operational and financial consequences that have global implications regarding equity and access.

This word salad essentially means “yeah, all these viruses can spread via airborne transmission, but since airborne precautions are annoying and expensive, you don’t really have to do them”. It provides legal and institutional cover for the medical bodies who are still refusing to acknowledge airborne spread of COVID-19 and implement proper infection control. Vague terms like “balance of risk,” “severity,” “individual and population immunity,” all leave open an incredibly dangerous window for continued spread of COVID in medical settings; especially as one man’s “mild” is, quite literally, another man’s “severe”.

The terms “severity” and “population immunity” serve as a dog whistle to let government bodies and medical institutions know, yes, we did finally have to acknowledge that COVID is airborne. But don’t worry, this doesn’t mean we’re actually going to make you do airborne infection control. If you think it’s okay for your patients to contract COVID, it’s a-ok by us too! “Immunity” in particular is a highly-abused term in the context of COVID; most people achieve a temporary immunity from vaccination and/or infection, which rapidly fades. In an effort to normalize continual reinfection, our governments began conflating this short-term, rapidly fading protection that varies from person to person with the lifelong protection formerly known as “immunity”, a term which better applies to diseases like measles or chickenpox. Herd or population immunity in the context of measles means vulnerable people are never exposed to measles. Herd immunity in the context of COVID means vulnerable people are constantly exposed to COVID. It’s all very “war is peace.”

A note on the claim that “equity” and “access” are the true motivators behind the WHO’s poor guidance. Here, the body is attempting to argue that, because poor countries cannot afford proper airborne infection control, no one should have access to proper airborne infection control; hooray, that’s equity! Aside from the patent ridiculousness of this argument, let’s compare this with claims the WHO made four years ago vis-a-vis the same topic, while still claiming that airborne spread wasn’t happening.

Email from WHO Health Operations, Infection Prevention and Control Technical Team to Group 36, April 11, 2020:

The basis for the content of WHO guidance is as follows:

1) current evidence on SARS-CoV-2 predominant modes of transmission and lessons learned from the evidence on SARS, MERS and other respiratory viral infections;

2) direct experience with COVID-19 patients by frontline workers, epidemiologists, virologists and other scientists;

3) input, discussions and consensus by a large group of international independent experts in the fields of infectious diseases, epidemiology, public health and infection prevention and control, with special focus on viral respiratory infection (captured through our COVID-19 global expert network teleconferences);

4) global perspective including equity, ethical, and implementation considerations of WHO guidelines.

The latter is important for a global organization that needs to take into consideration capacity across health systems in different countries; however, under no circumstances does this aspect overcome available evidence. WHO is always reviewing available evidence and will adapt guidance based on this evidence – as always done for all infectious hazards. COVID-19 is no different. Would there be evidence of significant spread of SARS-CoV-2 as an airborne pathogen outside of the context of AGPs, WHO would immediately revise its guidance and extend the recommendation of airborne precautions accordingly despite the known limited capacity to apply them in all countries, in particular in low- and middle-income countries.

Emphasis mine. There, in black and white, the WHO contradicts its new guidance, stating in no uncertain terms that if COVID were airborne (it is), airborne infection control measures should be and would be recommended, even given the difficulties and expense of instituting such protocols.

Proper infection control guidance should do one basic thing: ensure that infections are controlled. Ensure that patients are not needlessly exposed to viruses- of any kind- while seeking medical care. The revolutionary progress we’ve made in understanding the behavior of viruses over the past several years, coupled with the fantastic technology that already exists to clean the air, would mean a much healthier society if that progress were applied practically. Instead, we’re becoming a much sicker society as the WHO sinks further into denial.

This document exists to handhold a small group of elite scientists who were incredibly, undeniably, dangerously wrong, and allow them to continue pushing their failed model of “infection control” which does not, in fact, control infections. It exists to assuage their damaged and bruised egos while assuring them they weren’t wrong to tell people to stand six feet apart and wipe down surfaces and cover their sneezes; this is, after all, the most practical and feasible form of infection control to implement even if it turns out the virus itself maybe, kind of, sort of, spreads in a completely different way.

The damage of the WHO’s false claims continue to reverberate today. Doctors and hospitals continue to infect their patients with flu, RSV, strep, and now COVID as infection control measures like HEPA filtration go completely unmentioned in the new guidance document. Hospitals continue to place highly infectious patients close to COVID-negative patients, falsely believing that curtains and a few feet of distance will protect vulnerable sick people. Doctors and nurses continue to lack proper PPE, while acquiring Long COVID at high rates and dealing with out-of-control hospital crowded all over the world. And perhaps most damaging at all, the public has been lulled into a sense of complacency and encouraged to believe that COVID simply cannot be controlled. Unaware that the protocols implemented in 2020 were plainly incorrect for mitigation and elimination, the defeatist refrain rings out everywhere, “COVID is here to stay, there’s nothing we can do.”

The WHO has a responsibility to engage seriously with the science of airborne infection control and make recommendations that minimize the spread airborne disease- not recommendations that seek instead to minimize its own embarrassment and responsibility.

"The Goal of The Campus Jew-haters" - by David Horowitz

Here is a must-read opinion piece by David Horowitz at The Times of Israel. Click the link to read the original column, which includes very disturbing Twitter posts that I couldn't figure out to paste in.

---------------------------

The goal of the campus Jew-haters: To render Israel indefensible, in both senses of the word

The aggression against Israel and Jews would not be tolerated if aimed at any other minority; its defenders are unforgivably prioritizing free speech above the intended deadly consequences

While Jews have been celebrating the first days of Passover, the ancient festival of freedom, antisemites and their useful idiot collaborators on a swelling number of American university campuses have been rallying and issuing murderous threats in a strategic effort to end Jewish freedom, in the here and now, by destroying the world’s only Jewish majority state.

The underlying goal of the encampments and marches at Columbia, Yale, NYU and the other campuses is to render Israel indefensible — in both senses of the word.

The strategy:

First, to misrepresent what Israel has been subjected to and how it has responded since Hamas invaded our country on October 7, slaughtered 1,200 people, abducted 253 hostages, and then hid behind and beneath Gaza’s civilians in a bid to survive and do it all again.

Second, to falsely brand Israel as a brutal and indifferent aggressor, solely responsible for a soaring Gaza death toll that would, in fact, total precisely zero were it not for Hamas’s genocidal ambitions for the Jews and indifference to the lives of Gazan civilians.

Third, to build pressure for divestment from Israel, for an end to military aid, and ultimately for the severing of Israel’s vital alliance with the United States.

And, finally, to thus deprive Israel of the diplomatic and military means to survive the ongoing effort at its destruction, as effected by Iran and its allies and proxies.

At the root of this strategy is, of course, the oldest of hatreds.

The antisemitism is stirred in this case by Muslim extremists, racists, ignoramuses and self-hating Jews; “inspired” on social media, and partly funded openly and covertly by states seeking Israel’s demise.

And it is being tolerated in an environment that seems to prioritize limitless free speech over the violent consequences of the abuse of that freedom.

To the university administrations and faculty members defending, enabling and even rallying in support of the activists’ ostensible rights to viciously denounce Israel and Jews with calls to burn Tel Aviv, kill soldiers and threaten Jewish students with murder by Hamas, one must put the question: Is the right to free speech unlimited, to be upheld even when the goal and likely potential consequence is deadly?

As the British-Palestinian writer John Aziz has noted, this is “the rhetoric of mass murder.”

"I'm Palestinian, not Jewish or Israeli. But if I was a student at one of these Ivy League universities, I'd get the hell out of there. 'Militancy breeds resistance'? This rhetoric is the rhetoric of mass murder. They're talking about murdering people".

Were this level of hatred and aggression directed at any other minority group, it is hard to imagine that it would be indulged and tolerated, even at the price of limiting free speech. 

 But targeting the planet’s only Jewish majority state — and extending the hostility to Jews on campus and beyond — is evidently considered an exception, forgivable, even admirable.

That again, all you ostensibly ultra-humane and decent people who support these protests, is antisemitism

The initial goal of this inexcusably tolerated murderous hostility is to aid in Israel’s demise — by establishing our country as a pariah state, and rendering it untenable to be associated with, defended or protected. Protected, that is, from the amoral, rapacious, misogynistic, homophobic, and potent enemies who, as I write, are firing rockets from the north (Hezbollah), trying to do so from the south (Hamas), and advancing toward obtaining nuclear weapons in the east (Iran).

But if those enemy states, terrorist armies and their facilitators get done with Israel, they’ll be coming for Jews everywhere (and, no, membership in Jewish Voice for Peace won’t help), and, for that matter, for every other minority deemed unacceptable (sorry, Queers for Palestine).

At our family Seder night this year, I understood properly for the first time how it was that Rabbi Eliezer, Rabbi Yehoshua, Rabbi Elazar ben Azariah, Rabbi Akiva and Rabbi Tarfon, studying the story of the Exodus in Bnei Brak almost 2,000 years ago with their own urgent preoccupations, would, of course, have been talking all night, until their students came to remind them it was time for morning prayer.

And I thought at length for the first time — forgive me — of what it must have been like for Jews three or so generations ago to read the Haggadah during the Holocaust, trying to celebrate ancient deliverance while seeking to escape contemporaneous genocide

With 133 Israelis absent from the Seder, held in captivity by the monstrous Hamas, in a nation still coming to terms with October 7 — with our loss, vulnerability and the surging global hostility to the very fact of our existence — passage after passage took on immediate and extreme relevance.

How could it not?

Terrorism on Campus?

From Fox NewsFBI director has been sounding alarm on ‘heightened threat environment’: Is America listening?  FBI Director Christopher Wray has warned lawmakers that the threat of terrorism has risen to a whole other level since Oct. 7

Assuming that there are Hamas terrorists and other Jihadists already in our country thanks to our borderless condition, imagine the damage they can do by embedding themselves on college campuses,  with the full support of the anti-Israel, pro-Hamas extremists already there.  All they would have to do is set off some suicide bombs, or attack the Jewish organizations.

The question should not only be "Is America listening?"  It should also be "Is anyone prepared for coordinated Hamas attacks on campuses nationwide?"

Tuesday, April 23, 2024

Campus Nazis Are Now "Anti-War Protesters".

This was the headline of the email I received today from The Washington Post:

U.S. News Alert: More than 130 Israel-Gaza war protesters were arrested at NYU, police say. Columbia is offering hybrid classes amid demonstrations.

When you click the link, you get this:

Police arrest 133 NYU antiwar protesters; Calif. students form barricade.

So now these violent anti-Israel, anti-Jewish terrorists are being called "antiwar protesters" by the press to downplay & disguise their hatred.

Anyone who saw the violence and rioting on TV wasn't fooled.   The girl that shrieked "We Are Hamas! I love Hamas!"  The hate-filled signs. The fact that Jewish students were warned by the rabbi to leave campus for their own safety. 

It is pure, unadulterated antisemitism 

These college presidents should be fired and the National Guard called out before things get even worse for the Jews and even better for Hamas.

Dr Ruth's COVID news & more Newsletter for 4/23/24

Here's the latest very informative newsletter from Dr Ruth Ann Crystal:

"Wastewater levels are “LOW” across the US and hospitalizations, emergency department visits and deaths from COVID have decreased even more. JN.1 and its descendants are responsible for almost all COVID cases now. In the Bay Area, Santa Clara county is in the “MEDIUM” level for SARS-CoV-2 in wastewater. Stanford had a huge spike of wastewater virus a few days ago that has now resolved. There are also HIGH viral wastewater levels of SARS-CoV-2 in Mill Valley, and MEDIUM levels in Sausalito and San Rafael. Although numbers are low nationally, I personally know four people who have had a COVID infection in the last week. According to JP Weiland, about 1 in every 164 people is currently infected and there are about 200,000 new COVID cases per day across the United States. You can see wastewater levels for your county by searching on Wastewater SCAN.

"Although we are at low virus levels for the U.S. now, variant hunters on Twitter have alerted that new JN.1 descendants with the FLiRT mutation (subvariants KP.3, KP.2, KS.1, KP.1.1) have a significant growth advantage over JN.1 and therefore may cause another COVID wave(let) in the next 6 weeks. According to Eric Topol MD and JP Weiland, JN.1 + FLiRT subvariants will probably not cause a very large wave, since our collective immune systems have seen the FLiRT mutation in past variants and since the JN.1 wave just recently happened. The latest COVID vaccine (against XBB.1.5) does provide protection against JN.1 for hospitalization and death for at least several months. We do not know yet if this vaccine will work against JN.1 + FLiRT subvariants yet, but the feeling is that the XBB.1.5 vaccine should offer at least some protection. Seniors and immunocompromised people should get their second dose of the XBB.1.5 vaccine soon.

Figure: Ben Murrell shows the growth advantage of JN.1 + FLiRT subvariants (KP.3, KP.2, KS.1, KP.1.1)

Acute COVID infections, General COVID info

"An eye-opening article came out showing that airborne SARS-CoV-2 virus can linger in a room and can infect others almost 5 hours after an infected person leaves a room. The authors used whole genome sequencing (WGS) and discovered that "genetically identical SARS-CoV-2 infected two patients who were admitted to a hospital room 1 hour, 43 minutes and 4 hours, 45 minutes after discharge of an asymptomatic infected patient".

"Remdesivir made some news. Patients who did not require oxygen on admission to the hospital, but were treated with Remdesivir were found to have 25% reduction in in-hospital mortality compared to non-remdesivir treatment at 14 days and a 17% decrease in in-hospital mortality compared to non-remdesivir treatment at 28 days. The reduction in in-hospital mortality from giving Remdesivir at hospital admission was seen with all COVID variants.

"The microbiome refers to the community of microorganisms (such as fungi, bacteria and viruses) that normally live in different parts of our bodies such as in the gastrointestinal system or the skin. A new study of the saliva of people with an acute COVID infection showed that the “oral microbiome and salivary cytokines may be predictive of COVID-19 status and severity.”

"The SARS-2 virus can infect both exocrine and endocrine cells in the pancreas. A new study shows that COVID infection can cause increased insulin resistance, and even a loss of beta cells that make insulin. The loss of beta cells was associated with lower insulin production with islet amyloidosis and necrosis. Fortunately, vaccination against COVID was shown to help with glucose homeostasis by activating insulin receptor α and insulin receptor β. The authors noted "Overall, the cumulative risk of diabetes post-COVID-19 is closely tied to age, suggesting more attention should be paid to blood sugar management in elderly COVID-19 patients."

"There were two other studies this week on age-dependent responses to SARS-2 infection. Older adults can be more susceptible to severe COVID infections. Using mass cytometry, serum proteomics, antibody assays, and transcriptional analysis, a group found that older age was associated with increased viral load, reduced ability to clear the virus, and dysregulation of immune signaling. Older adults also had higher expression of pro-inflammatory genes and proteins with severe COVID infections. In addition, herpes simplex virus and cytomegalovirus (CMV) were reactivated in the upper airways of older adults. 

"Another group looked at age-specific responses to SARS-CoV-2 infection in the nasal epithelial lining and found differences in the types of cells found in the nose. In children (<12 years old), a distinct goblet inflammatory cell was seen in the cells lining their noses, along with high interferon levels which stopped viral replication. In older adults (>70 years), nasal epithelial cells infected with SARS-2 showed an increase in basaloid-like cells, which helped the virus spread. Differing amounts of ACE2 and TMPRSS2 receptors were found in nasal epithelial cells in different age groups. 

From: https://www.nature.com/articles/s41564-024-01658-1

Vaccines and antiviral medications

"A modeling study of hybrid immunity from infection and from vaccination showed that the immunity wall from prior COVID infection does not last very long if people are not also vaccinated. Without vaccination, people can become reinfected with the same variant a few months after their first infection. Higher vaccination levels in a community provided a better immunity wall to stop secondary reinfections with the same variant.

"Newer mutations help the SARS-2 virus to escape from some monoclonal antibodies that worked against prior variants. A group isolated 28 potent monoclonal antibodies and found that some of them regained the ability to neutralize newer variant BA.2.86. JN.1 is a descendant variant of BA.2.86.

"A new study from Yale shows that neosporin ointment placed in the nose may help prevent COVID and the flu. Intranasal generic antibiotic neomycin increased interferon expression in the nose and protected mice and hamsters from COVID infection and from Influenza A. In humans, Neosporin was also found to increase antiviral interferon expression in the nose. 

Long COVID

"On April 15, Dr. Jeremy Faust interviewed NIH Director Monica Bertagnolli MD. During their conversation, Dr. Bertagnolli said that data shows that live SARS-CoV-2 virus can persist in tissues for months or even years. She also discussed the need for better antiviral medications to stop viral reservoirs in the body to possibly prevent Long COVID. This was the first time that someone from the government said that there are definitely viral reservoirs of SARS-CoV-2 in the body.

"From their interview:

“Faust: I just want to follow up on something you said a moment ago about where this virus can be found in tissues. Are you suggesting that Long COVID is actually, the mechanism of that persistent live virus in humans?

Bertagnolli: We see evidence of persistent live virus in humans in various tissue reservoirs, including surrounding nerves, the brain, the GI [gastrointestinal] tract, to the lung.

Faust: OK. And you're saying this goes beyond the PCR's [polymerase chain reaction test] ability to get it in a regular swab so that we are missing chronic cases of SARS‑CoV‑2?

Bertagnolli: Correct. The virus can persist in tissues for months, perhaps even years.

Faust: OK. I think that's certainly one theory, but I'm not sure that that's settled. Is that fair? I mean, there's one thing between people who are autopsy, they died of viral sepsis, as opposed to people walking around. Is there a distinction there?

Bertagnolli: Our emerging data shows that the virus can persist into tissues in the long term, and I think that's really critical because it does help us think about possible ways to combat it, one being better antivirals. I think there's a lot of focus on developing new antivirals as a possible way of preventing long COVID, and the other might be more aggressive treatment with antiviral therapy upon initial diagnosis.”

Share

"This week, a study in Nature magazine stated that many people with Long COVID have resolution of immune dysregulation at 24 months. But, this study had many flaws. The authors’ definition of Long COVID was if someone had “fatigue, dyspnea or chest pain.” They did not study people with cognitive dysfunction, orthostatic intolerance, sleep disturbances or post-exertional malaise. More than 20% of their Long COVID patients were lost to follow-up. In addition, some people with Long COVID in the study were reinfected within the 24 months. While they said that immune dysregulation had resolved by 24 months, their data showed that people with Long COVID still had significant EBV T-cell exhaustion at 24 months. There are a lot of problems with this study and I anticipate that it will be retracted or changed.   

"Congratulations to Professor Akiko Iwasaki of Yale who was named one of TIME magazine’s 100 most influential people! Dr. Iwasaki studies how the immune system fights off viruses at mucosal surfaces. More recently, she has been investigating the pathophysiology of Long COVID and has been working on a mucosal vaccine against SARS-CoV-2.

ME/CFS and Long COVID

"Elite athletes test their lactate levels to see if they have pushed their bodies into anaerobic respiration. A group from the UK suggests that lactate monitoring could also be used in people with ME/CFS and with Long COVID to see when they switch to anaerobic respiration to produce energy. Aerobic respiration takes place in the mitochondria and is very efficient at producing 38 ATP molecules from oxygen. In contrast, anaerobic respiration is not efficient- it only makes 2 ATP energy molecules and produces lactate as a waste product. People with Long COVID are not able to extract oxygen in their muscles and tissues like healthy people can, and therefore, they rely on anaerobic metabolism more often. Anaerobic metabolism in people with ME/CFS and Long COVID is thought to be one reason why they get post-exertional malaise from minimal movement or exercise. As ME Research UK stated, “monitoring blood lactate levels may provide an indication of abnormally increased anaerobic respiration in those with ME/CFS and Long COVID, but more research is needed.”

From: https://twitter.com/MEResearchUK/status/1779872308452065313

"A new NIH initiative is trying to find out if Long COVID and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) are the same disorder. Authors in Neurology Today reviewed an excellent article from Feb 21, 2024 from the NIH on post-infectious myalgic encephalomyelitis/ chronic fatigue syndrome (PI-ME/CFS). Dr. Avindra Nath stated “We believe these [ME/CFS and Long COVID] are virtually the same disease, … and they should be managed and studied in multidisciplinary clinics focused on post-infectious syndromes.” 

"Below is the summary slide from the February article which shows COVID infection causes abnormal changes in the microbiome of the gut. This, in combination with immune dysfunction, leads to decreased metabolites that are used to make neurotransmitters in the brain. The lower levels of tryptophan and other metabolites causes several things to happen in the brain which then affect the heart and the skeletal muscles.

  • The catecholamine nuclei in the brain release less catechols, which affects the autonomic nervous system causing increased sympathetic function and decreased parasympathetic activity leading to decreased heart rate variability.

  • Abnormalities in the Hypothalamus decrease activation of the right temporoparietal junction which affects motor cortex function and leads to decreased motor strength.  

"Together, autonomic dysfunction of the heart and central motor dysfunction via the brain leads to decreased muscle strength which is seen as a decrease in physical activity and ability. 

Fig. 10: Pathophysiology of PI-ME/CFS
----------------
See more charts and graphs here at Dr Ruth's website.